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Your search keyword '"A. S. Santoro"' showing total 3 results
Start Over Author "A. S. Santoro" Journal minerva ginecologica
3 results on '"A. S. Santoro"'

1. [Study of a topical antibacterial, contraceptive, antifungal and anti-venereal pharmacological combination. III. Post-coital test of the spermicidal action of a combination of oxyquinoline sulfate, copper sulfate and lactic acid]

Author

F, Franchi, S, Santoro, F, Crescenzi, C, Santoro, and M, Ivaldi

Subjects
Adult, Male, Antifungal Agents, Coitus, Sexually Transmitted Diseases, Oxyquinoline, Drug Combinations, Contraceptive Agents, Anti-Infective Agents, Local, Hydroxyquinolines, Lactates, Sperm Motility, Humans, Female, Copper
Abstract

30 fertile couples volunteered to test a new spermicidal vaginal cream. The cream, an association of oxyguinoline sulphate, copper sulphate, and lactic acid, was applied before and during intercourse. Postcoital tests were done with material taken from the posterior fornix and from the cervical mucus to investigate the presence and motility of spermatozoa. No mobile forms were found, while preceding spermiograms had evaluated that count, motility, and morphology of the partners' spermatozoa were perfectly normal. From these results it can be stated that the drug can be a valid alternative to oral or intrauterine contraception, being safe, easy, cheap, and without side effects.

Published
1979

2. [Study of a drug combination for topical use, with contraceptive, antibacterial, antimycotic and prophylactic action for venereal diseases. I. Effect of oxyquinoline sulfate and copper sulfate on the motility and morphology of human spermatozoa in vitro]

Author

M, Ivaldi, F, Mazzilli, S, Santoro, F, Fraioli, and F, Dondero

Subjects
Drug Combinations, Sulfates, Drug Evaluation, Preclinical, Hydroxyquinolines, Humans, Sperm Immobilizing Agents, In Vitro Techniques, Oxyquinoline, Spermatocidal Agents, Copper
Published
1979

3. [Study of a drug combination for topical use, with contraceptive, antibacterial and antimycotic action and venereal disease preventive action. II. Optical microscopic and scanning microscopic studies of morphological changes of human spermatozoa in vitro after contact with the oxyquinoline sulfate and copper sulfate association]

Author

M, Ivaldi, F, Mazzilli, S, Santoro, F, Crescenzi, and C, Santoro

Subjects
Male, Drug Combinations, Sulfates, Hydroxyquinolines, Microscopy, Electron, Scanning, Humans, Sperm Immobilizing Agents, In Vitro Techniques, Oxyquinoline, Spermatocidal Agents, Spermatozoa, Copper
Abstract

A new spermicidal contraceptive agent consisting of an association of oxyquinoline sulfate and copper sulfate was tested in vitro to study its morphological effects on fresh sperm. Notable changes, such as a crumpling of the head, and variations in linear geometry of spermatozoa, were noted at the optic microscope. The scanning microscope discovered further erosions at the head and at the neck membranes level. It would be advisable to further study the association of these 2 drugs, to be eventually used as a strong topical spermicidal agent, and as a valid alternative to hormonal contraception.

Published
1979

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