1. Recognizing the Benefits of Pre-/Probiotics in Metabolic Syndrome and Type 2 Diabetes Mellitus Considering the Influence of Akkermansia muciniphila as a Key Gut Bacterium
- Author
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Mirela Marioara Toma, Areha Abid, Simona Bungau, Ovidiu Fratila, Felicia Liana Andronie-Cioara, Aurelia Cristina Nechifor, Raluca Anca Corb Aron, Timea Claudia Ghitea, Mihai Alexandru Munteanu, Cosmin Mihai Vesa, and Tapan Behl
- Subjects
0301 basic medicine ,Microbiology (medical) ,type 2 diabetes mellitus ,030209 endocrinology & metabolism ,Review ,Gut flora ,Microbiology ,digestive system ,metabolic syndrome ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Virology ,medicine ,lcsh:QH301-705.5 ,biology ,business.industry ,Type 2 Diabetes Mellitus ,biology.organism_classification ,medicine.disease ,030104 developmental biology ,lcsh:Biology (General) ,probiotics ,Immunology ,Metabolic syndrome ,gut bacterium ,business ,prebiotics ,Bacteria ,Akkermansia muciniphila - Abstract
Metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are diseases that can be influenced by the structure of gut microbiota, whose improvement is often neglected in metabolic pathology. This review highlights the following main aspects: the relationship between probiotics/gut microbes with the pathogenesis of MetS, the particular positive roles of Akkermansia muciniphila supplementation in the onset of MetS, and the interaction between dietary polyphenols (prebiotics) with gut microbiota. Therefore, an extensive and in-depth analysis of the often-neglected correlation between gut microbiota and chronic metabolic diseases was conducted, considering that this topic continues to fascinate and stimulate researchers through the discovery of novel strains and their beneficial properties.
- Published
- 2021