1. Comparative genome analysis of Prevotella ruminicola and Prevotella bryantii: insights into their environmental niche.
- Author
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Purushe J, Fouts DE, Morrison M, White BA, Mackie RI, Coutinho PM, Henrissat B, and Nelson KE
- Subjects
- Animals, Bacterial Proteins genetics, Bacterial Proteins metabolism, Molecular Sequence Data, Phylogeny, Prevotella classification, Prevotella enzymology, Prevotella isolation & purification, Prevotella ruminicola classification, Prevotella ruminicola enzymology, Prevotella ruminicola isolation & purification, Rumen microbiology, Genome, Bacterial, Prevotella genetics, Prevotella ruminicola genetics
- Abstract
The Prevotellas comprise a diverse group of bacteria that has received surprisingly limited attention at the whole genome-sequencing level. In this communication, we present the comparative analysis of the genomes of Prevotella ruminicola 23 (GenBank: CP002006) and Prevotella bryantii B(1)4 (GenBank: ADWO00000000), two gastrointestinal isolates. Both P. ruminicola and P. bryantii have acquired an extensive repertoire of glycoside hydrolases that are targeted towards non-cellulosic polysaccharides, especially GH43 bifunctional enzymes. Our analysis demonstrates the diversity of this genus. The results from these analyses highlight their role in the gastrointestinal tract, and provide a template for additional work on genetic characterization of these species.
- Published
- 2010
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