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Your search keyword '"Teixeira, G."' showing total 4 results
Start Over Author "Teixeira, G." Journal memorias do instituto oswaldo cruz
4 results on '"Teixeira, G."'

1. Molluscicidal activity of Physalis angulata L. extracts and fractions on Biomphalaria tenagophila (d'Orbigny, 1835) under laboratory conditions

Author

José Augusto A dos Santos, Therezinha Coelho B Tomassini, Deise Cristina Drummond Xavier, Ivone Maria Ribeiro, Melissa Teixeira G da Silva, and Zenildo Buarque de Morais Filho

Subjects
molluscicidal activity, Physalis angulata L., Solanaceae, Biomphalaria tenagophila, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216
Abstract

The main objective of this research is to evaluate the molluscicide activity of Physalis angulata L. Biomphalaria tenagophila specimens under laboratory conditions. Extracts and fractions were supplied by the Laboratório de Química de Produtos Naturais, Farmanguinhos-Fiocruz. Experiments were performed according to the methodology described by the World Health Organization for molluscicide tests using the concentrations from 0.1 to 500 mg/l of the extracts, fractions and of a pool of physalins modified steroids present in this species. The results show that ethyl acetate and acetone extracts from the whole plant, the ethanolic extracts of the roots and the physalins pool from stems and leaves were active. Only the whole plant extracts were available in sufficient quantity for the determination of LD50 and LD90 values.

Published
2003
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2. Studies on antimicrobial activity, in vitro, of Physalis angulata L. (Solanaceae) fraction and physalin B bringing out the importance of assay determination

Author

Terezinha G. F. M. Batista, Melissa Teixeira G da Silva, Paola Cardarelli, Sonia M. Simas, and Therezinha C. B. Tomassini

Subjects
Microbiology (medical), lcsh:Arctic medicine. Tropical medicine, food.ingredient, Physalis, lcsh:RC955-962, lcsh:QR1-502, Drug Evaluation, Preclinical, Physalis angulata, Microbial Sensitivity Tests, Gram-Positive Bacteria, medicine.disease_cause, lcsh:Microbiology, Microbiology, Agar dilution, Lactones, chemistry.chemical_compound, food, Candida albicans, Gram-Negative Bacteria, medicine, Secosteroids, Agar, Escherichia coli, physalins, antimicrobial methods, biology, Plant Extracts, biology.organism_classification, Antimicrobial, Anti-Bacterial Agents, Culture Media, Physalis angulata L, chemistry, Staphylococcus aureus, Physalin, Steroids
Abstract

Complex physalin metabolites present in the capsules of the fruit of Physalis angulata L. have been isolated and submitted to a series of assays of antimicrobial activity against Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 29213, S. aureus ATCC 25923, S. aureus ATCC 6538P, Neisseria gonorrhoeae ATCC 49226, Escherichia coli ATCC 8739; E. coli ATCC 25922, Candida albicans ATCC 10231 applying different methodologies such as: bioautography, dilution broth, dilution agar, and agar diffusion techniques. A mixture of physalins (pool) containing physalins B, D, F, G inhibit S. aureus ATCC 29213, S. aureus ATCC 25923, S. aureus ATCC 6538P, and N. gonorrhoeae ATCC 49226 at a concentration of 200 mg/microl, using agar dilution assays. The mixture was inactive against P. aeruginosa ATCC27853, E. coli ATCC 8739; E. coli ATCC 25922, C. albicans ATCC 10231 when applying bioautography assays. Physalin B (200 microg/ml) by the agar diffusion assay inhibited S. aureus ATCC 6538P by +/- 85%; and may be considered responsible for the antimicrobial activity.

Published
2005
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