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Start Over Author "Khrapova Np" Journal meditsinskaia parazitologiia i parazitarnye bolezni
2 results on '"Khrapova Np"'

1. [The outlook for improving the immunoglobulin preparations for the detection and identification of the causative agents of glanders and melioidosis].

Author

Khrapova NP, Tikhonov NG, Prokhvatilova EV, and Kulakov MIa

Subjects
Agglutination Tests methods, Agglutination Tests standards, Agglutination Tests statistics & numerical data, Animals, Burkholderia pseudomallei immunology, Hybridomas immunology, Immunodiffusion methods, Immunodiffusion standards, Immunodiffusion statistics & numerical data, Indicators and Reagents standards, Mice, Mice, Inbred BALB C, Pseudomonas immunology, Antibodies, Monoclonal isolation & purification, Burkholderia pseudomallei isolation & purification, Immunoglobulins isolation & purification, Pseudomonas isolation & purification
Abstract

The paper summarizes the data concerning the production and study of monoclonal antibodies (MAb) to the diagnostically significant glanders and melioidosis bacillus antigens. It evaluates the efficiency of using MAb in the gel immunodiffusion and agglutination tests as a basis of new-generation preparations for fluorescent antibody assay, indirect hemagglutination test which are used while detecting and identifying pathogenic pseudomonads. The paper defines the quality indices for monoclonal luminescent immunoglobulins and provides evidence for the benefits of monoclonal diagnostic agents over polyclonal analogues.

Published
1995

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