1. [Effect of biological preparation alfetin in infiltrative pulmonary tuberculosis].
- Author
-
Cherkasov VA, Permiakova NV, Maliutina NN, Peleneva IM, and Rodionov SIu
- Subjects
- Adult, Double-Blind Method, Humans, Injections, Intravenous, Male, Middle Aged, Occupational Diseases metabolism, Phospholipids blood, Pulmonary Surfactants metabolism, Treatment Outcome, Tuberculosis, Pulmonary metabolism, alpha-Fetoproteins administration & dosage, Occupational Diseases drug therapy, Tuberculosis, Pulmonary drug therapy, alpha-Fetoproteins therapeutic use
- Abstract
The authors evaluated influence of Alfetin new Russian biologic preparation on pulmonary surfactant system and phospholipid metabolism in workers at risk of occupational pneumoconiosis, who suffer from infiltrative pulmonary tuberculosis. Considering positive changes in serum phospholipids subunits under alfetin treatment, the authors proved membrane protective effect of the drug. Alfetin was proved to weaken toxic effects of tuberculostatic drugs on lung surfactant.
- Published
- 2004