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38 results on '"Yang, Jia"'

19. Efficacy and safety of laparoscopic holmium laser lithotripsy in the treatment of complicated biliary calculus

Author

Jin, Penghui, Jing, Wutang, Zhan, Weipeng, Han, Caiwen, Si, Moubo, Yang, Jia, Li, Yiping, Gu, Yuanhui, Ma, Yuntao, and Guo, Tiankang

Subjects
Common Bile Duct, Male, biliary calculus, holmium laser, Gallstones, Lasers, Solid-State, lithotripsy, Middle Aged, Lithotripsy, Laser, laparoscopic, Treatment Outcome, Case-Control Studies, Humans, Female, Laparoscopy, Systematic Review and Meta-Analysis, Research Article, meta analysis
Abstract

Backgroud: The aim of this study was to assess the efficacy and safety of laparoscopic holmium laser lithotripsy (LHLL) in the treatment of complicated biliary calculus. Methods: We systematically searched the electronic database (PubMed, EMBASE, Cochrane library, Web of science, and Chinese Biomedical Literature Database) up to May 2018 to identify case-controlled studies that compared LHLL with laparoscopic bile duct exploration (LBDE) for complicated biliary calculus. Results: Five case-controlled studies were included, with 541 patients (273 in the LHLL group and 268 in the LBDE group). Compared with LBDE, LHLL was associated with shorter operative time (weighted mean difference [WMD] = -40.04, P

Published
2019

20. Liver transplantation versus surgical resection for HCC meeting the Milan criteria

Author

Shen, Jun-Yi, Li, Chuan, Wen, Tian-Fu, Yan, Lv-Nan, Li, Bo, Wang, Wen-Tao, Yang, Jia-Yin, Xu, Ming-Qing, and Nazar Highness, Tholakkara

Subjects
Adult, Male, propensity scoring match, Carcinoma, Hepatocellular, liver transplantation, Platelet Count, Liver Neoplasms, Observational Study, Kaplan-Meier Estimate, Middle Aged, digestive system diseases, Disease-Free Survival, Survival Rate, hepatocelluar carcinoma, liver resection, Hepatectomy, Humans, Female, prognosis, alpha-Fetoproteins, Propensity Score, Research Article, Neoplasm Staging
Abstract

The optimal treatment (liver transplantation [LT] vs surgical resection [SR]) for early-stage hepatocellular carcinoma (HCC) remains controversial. A total of 209 SR patients and 129 LT patients were identified at our institution. After eliminating 27 patients with Child–Pugh C, the data from 209 SR patients and 102 LT patients were analyzed using a propensity score matching (PSM) model. Forty-six pairs were generated. A subgroup analysis was conducted based on the alpha-fetoprotein (AFP) level or platelet count (PLT). A survival analysis was performed using the Kaplan–Meier method. Gender, satellite lesions, and the treatment method were predictors of HCC recurrence. The Ishak score and treatment methods were associated with long-term survival after surgery. Before PSM, LT patients had a better prognosis than those treated by SR. Among HCC patients with childhood A/B cirrhosis, after PSM, SR achieved similar overall survival outcomes compared with LT. LT and SR resulted in comparable long-term survival for patients with or without thrombocytopenia. Patients with an AFP ≥ 400 ng/mL might achieve more survival benefits from LT. Our propensity score model provided evidence that, compared with transplantation, surgical resection could result in comparable long-term survival for resectable early-stage HCC patients, except for the AFP ≥ 400 ng/mL HCC subgroup. Surgical resection might not be a contraindication for early-stage HCC patients with thrombocytopenia due to their similar prognosis after transplantation.

Published
2016

26. Anterior approach combined with infrahepatic inferior vena cava clamping right hepatic resection for large hepatocellular carcinoma

Author

Zhou, Yan-Ming, Sui, Cheng-Jun, Zhang, Xiao-Feng, Li, Bin, and Yang, Jia-Mei

Subjects
Male, Carcinoma, Hepatocellular, infrahepatic inferior vena cava clamping, Liver Neoplasms, hepatic resection, Vena Cava, Inferior, Clinical Trial/Experimental Study, anterior approach, hepatocellular carcinoma, Middle Aged, Constriction, cardiovascular system, Hepatectomy, Humans, Female, Prospective Studies, Research Article
Abstract

Background: The anterior approach (AA) technique has been reported to provide better operative and survival outcomes compared with the conventional approach for large right hepatocellular carcinoma (HCC) resection. However, this technique runs the risk of massive retrograde bleeding from the right hepatic vein or middle hepatic vein at the deeper plane of parenchymal transection. This study was designed to evaluate the efficacy of AA combined with infrahepatic inferior vena cava (IVC) clamping on the perioperative outcomes in patients undergoing right hepatic resection for large HCC in randomized clinical trial settings. Methods: A total of 101 patients undergoing right hepatic resection for large HCC were randomized to receive AA combined with infrahepatic IVC clamping (group A, n = 50), or AA alone (group B, n = 51). Results: The total blood loss (423 ± 154 vs 757 ± 338 mL; P = 0.001), blood loss during liver transection (272 ± 96 vs 563 ± 144 mL; P = 0.001), and intraoperative blood transfusion requirements (12.0% vs 29.4%; P = 0.031) were significantly less in group A patients compared with group B patients. There was no IVC clamping-associated morbidity in group A. Conclusion: AA combined with infrahepatic IVC clamping for large right HCC resection is a safe, feasible, and effective technique in reducing intraoperative blood loss.

Published
2016

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