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Your search keyword '"SUN Chao"' showing total 19 results
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19 results on '"SUN Chao"'

12. Acquired diaphragmatic hernia in pediatrics after living donor liver transplantation

Author

Wang, Kai, Gao, Wei, Ma, Nan, Meng, Xing-Chu, Zhang, Wei, Sun, Chao, Dong, Chong, and Wu, Bin

Subjects
Hernia, Diaphragmatic, Male, Reoperation, diaphragmatic hernia, Infant, Prognosis, Liver Transplantation, pediatric, Postoperative Complications, Biliary Atresia, Child, Preschool, Living Donors, Humans, Female, Clinical Case Report, living donor liver transplantation, Research Article
Abstract

Rationale: Diaphragmatic hernia (DH) in pediatrics following living donor liver transplantation (LDLT) has been seldom reported in the past. Patient concerns: We report successful diagnosis and treatment of three pediatric cases with DH secondary to LDLT, discuss the possible etiology, and review the relevant literature. Diagnoses: The primary disease was biliary atresia and DH was diagnosed by computed tomography scan or x-ray of chest. Interventions: Laparotomy was performed successfully to repair the DH. Outcomes: The respiratory and digestive function was gradually recovered in 1 to 2 weeks after repair operation. In 2 to 8 months follow-up, patients were asymptomatic without any respiratory or digestive complications. Lessons: DH post-LDLT should be recognized as a possible complication when a left lateral segment graft is used. Careful clinical examination and prompt surgery could minimize complications.

Published
2018

19. Type 2 diabetes mellitus has a positive role in osteomyelitis: A Mendelian randomization analysis.

Author

Fu M, Qi H, Zhu S, Zhu D, and Sun C

Subjects
Humans, Genome-Wide Association Study, Risk Factors, Genetic Predisposition to Disease, Odds Ratio, Mendelian Randomization Analysis, Diabetes Mellitus, Type 2 genetics, Polymorphism, Single Nucleotide, Osteomyelitis genetics
Abstract

According to clinical evidence, type 2 diabetes mellitus (T2D) and osteomyelitis (OM) are currently the 2 major causes of mortality and morbidity in humans. Despite accounts of their coexistence, there is still no understanding of their fundamental connection. We attempted to assess the causal effect of T2D on OM using the two-sample Mendelian randomization method. The whole gene-wide association study's aggregate data were examined. Single-nucleotide polymorphisms, which have a substantial correlation with T2D, were used as instrumental variables in a two-sample Mendelian randomization (MR) analysis to assess the causal relationship between T2D and OM risk using the inverse variance weighting, MR-egger regression, and weighted median approaches, respectively. A total of 114 single-nucleotide polymorphism were used as instrumental variables in this analysis. The inverse variance-weighted analysis showed a significant causal relationship between T2D and OM, indicating that T2D has a detrimental effect on OM risk. The odds ratio for the causal effect of T2D on OM was 1.317, with a 95% confidence interval of (1.140, 1.522) (P < .001). To assess heterogeneity, Cochran Q test statistics and MR-Egger regression were applied in the inverse variance-weighted technique. The P-value of .737 indicated a considerable level of heterogeneity was not absent in the data. This study used Mendelian randomization analysis to establish a causal relationship between T2D and OM. The findings suggest that T2D may increase the risk of OM., Competing Interests: The authors have no conflicts of interest to disclose., (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)

Published
2024
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