1. Evaluation of the gestational diabetes mellitus diagnostic criteria recommended by the international association of diabetes and pregnancy study group for long-term maternal postpartum outcomes in mainland China
- Author
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Huixia Yang, Hong-Hua Wu, Weijie Sun, Difei Lu, Xiaohui Guo, Zhirong Miao, Yang-Zi Zhang, and Jun-Qing Zhang
- Subjects
Adult ,medicine.medical_specialty ,China ,endocrine system diseases ,long-term postpartum outcomes ,Observational Study ,Impaired glucose tolerance ,03 medical and health sciences ,0302 clinical medicine ,Insulin resistance ,Pregnancy ,Diabetes mellitus ,Insulin-Secreting Cells ,medicine ,Humans ,Body Weights and Measures ,030212 general & internal medicine ,IADPSG diagnostic criteria ,Glucose tolerance test ,medicine.diagnostic_test ,Obstetrics ,business.industry ,Postpartum Period ,nutritional and metabolic diseases ,Type 2 Diabetes Mellitus ,General Medicine ,Glucose Tolerance Test ,medicine.disease ,Lipids ,gestational diabetes mellitus ,Gestational diabetes ,Diabetes, Gestational ,Glucose ,030220 oncology & carcinogenesis ,Gestation ,Female ,Insulin Resistance ,business ,Research Article - Abstract
The gestational diabetes mellitus (GDM) diagnostic criteria recommended by the International Association of Diabetes and Pregnancy Study Group (IADPSG) were established based on the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study and have been the most commonly used criteria for determining GDM worldwide. Although individuals from mainland China were not included in the HAPO study, the IADPSG criteria have been used in China since 2011. However, the appropriateness of the criteria for evaluating maternal postpartum outcomes in mainland China are unknown. We conducted this study to determine whether the IADPSG criteria are appropriate for Chinese patients for evaluating long-term maternal postpartum outcomes. Eighty-four patients who were diagnosed with hyperglycemia during pregnancy and had delivery in Peking University First Hospital from February 2007 to December 2009 were enrolled in the study. For patients in Group A, GDM was diagnosed using both the National Diabetes Data Group (NDDG) and the IADPSG criteria, while patients in Group B, gestational impaired glucose tolerance (GIGT) was diagnosed using the NDDG criteria while GDM was diagnosed based on the IADPSG criteria. Anthropometric data, glucose metabolism, lipid profiles, β cell function, and insulin resistance index were evaluated and compared to baseline after 5- to 6-year postpartum period. Patients in group A had significantly higher oral glucose tolerance test (OGTT) fasting, 2-hour and 3-hour plasma glucose levels compared to patients in group B at 24 to 28 weeks of gestation (P
- Published
- 2020