1. Analysis of factors related to preterm birth: a retrospective study at Nanjing Maternity and Child Health Care Hospital in China
- Author
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Hongjuan Ding, Yating Qian, Jin Huang, Ruizhe Jia, Lei Zhang, and Mingming Gao
- Subjects
Adult ,China ,Fetal Membranes, Premature Rupture ,medicine.medical_specialty ,Placenta Previa ,Observational Study ,interaction ,Prom ,Chorioamnionitis ,03 medical and health sciences ,multivariate ,0302 clinical medicine ,Pregnancy ,Risk Factors ,Infant Mortality ,medicine ,Humans ,Mass index ,030212 general & internal medicine ,Retrospective Studies ,Obstetrics ,business.industry ,Infant, Newborn ,Infant ,preterm birth ,Retrospective cohort study ,General Medicine ,medicine.disease ,Placenta previa ,Gestational diabetes ,Diabetes, Gestational ,Logistic Models ,030220 oncology & carcinogenesis ,Premature Birth ,Female ,heterogeneity ,business ,Body mass index ,Research Article - Abstract
Preterm birth is the most important cause of neonatal mortality and morbidity worldwide. The aim of this study was to identify factors associated with preterm birth and examine the heterogeneity and interactions between these factors. We collected data from 1607 pregnant women treated at Nanjing Maternity and Child Health Care Hospital in China. The women included in the study were divided into the full-term group and the preterm-birth group. We used t-tests to compare the characteristics of age and body mass index, Chi-square tests for the other variables, and we used the Wald test to calculate the interaction between factors that may affect preterm birth. The heterogeneity test was used to study the relationship between subgroups. Multivariable logistic regression analysis was used to explore the associations between risk factors and preterm birth, which included all risk factors. All tests were 2-tailed, P < 0.05 was considered significant, and 95% confidence intervals were estimated for percentages. There was no statistical difference in basic characteristics such as age between the full-term and preterm groups. We found 6 independent risk factors that were associated with preterm birth (P
- Published
- 2020