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Background and Objective: Avascular necrosis of femoral head (AVN) has been identified as a frequent complication after hematopoietic stem cell transplantation (HSCT). Advances in the treatment for haematological malignancies have improved survival after HSCT. The aim of this study was to report the short and medium-term results of total hip arthroplasty for the treatment of AVN., Patients and Method: We performed 12 consecutive total hip arthroplasties (THA) with at least 2 year follow up. The diagnosis was AVN in the context of HSCT. Except for one, in all the patients THA was the first surgical procedure., Results: On the Merle D'Augbigne and Postel grading system, 83% hips were good or excellent. There were no revisions for septic or aseptic loosening., Conclusions: We conclude that, in our experience, THA provided a good short and medium term follow up in patients with AVN after HSCT, and it seems to be a safe and effective treatment and the best option after conservative treatment failure.

Backgrounds and Objective: Direct exchange using antibiotic-impregnated cement is a treatment option for hip prosthesis infection (HPI). Nevertheless, a local antibiotic use is not always possible. We present our experience with direct exchange with and without antibiotic-impregnated cement., Patients and Method: Fourteen patients with a HPI were treated with direct exchange. The femoral component was cemented with an antibiotic in 7 cases and in 7 it was not cemented. The patients received antibiotic prophylaxis and antibiotic treatment for a mean of 3 months. Clinical evolution of the infection was prospectively assessed., Results: There were no differences with regard to the clinical and microbiologic characteristics between both groups. In the last control (minimum 2 years) all the patients were cured., Conclusions: Our results suggest that direct exchange without local antibiotic is an option in HPI. Further studies are needed to evaluate the usefulness of antibiotic loaded cement.