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Your search keyword '"Dunja Wilmes"' showing total 2 results
Start Over Author "Dunja Wilmes" Journal medical mycology case reports
2 results on '"Dunja Wilmes"'

1. Disseminated coccidioidomycosis: Monitoring of serologic markers for treatment response

Author

Dunja Wilmes, Daniela Schui, Jürgen Held, Sina Ackermann, Udo Geipel, Kai Emrich, Ernst-Joachim Winkelmann, and Volker Rickerts

Subjects
Coccidioidomycosis, Endemic mycosis, travel Related diseases, Osteomyelitis, Coccidioides qPCR, Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

We describe a patient with a disseminated coccidioidomycosis. Biomarkers in serum during itraconazole therapy showed a rapid clearing of Coccidioides DNA as detected by PCR. Coccidioides antibody detection by lateral flow assay became negative after one year and decreased from 1:64 to 1:8 in the complement fixation test after two years. The (1 → 3)-ß-D-glucan levels normalised after two years without increase after cessation of antifungal therapy. Biomarkers in serum may guide treatment decisions in disseminated coccidioidomycosis.

Published
2020
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2. Disseminated coccidioidomycosis: Monitoring of serologic markers for treatment response

Author

Udo Geipel, Volker Rickerts, Dunja Wilmes, Sina Ackermann, Daniela Schui, Kai Emrich, Ernst-Joachim Winkelmann, and Jürgen Held

Subjects
0301 basic medicine, Treatment response, Itraconazole, 030231 tropical medicine, 030106 microbiology, travel Related diseases, Disseminated coccidioidomycosis, Case Report, Microbiology, Serology, 03 medical and health sciences, 0302 clinical medicine, Endemic mycosis, Medicine, Coccidioides, ddc:610, lcsh:QH301-705.5, lcsh:R5-920, Coccidioidomycosis, biology, business.industry, Osteomyelitis, medicine.disease, Complement fixation test, biology.organism_classification, Infectious Diseases, lcsh:Biology (General), Coccidioides qPCR, Immunology, business, 610 Medizin und Gesundheit, lcsh:Medicine (General), medicine.drug, Antibody detection
Abstract

We describe a patient with a disseminated coccidioidomycosis. Biomarkers in serum during itraconazole therapy showed a rapid clearing of Coccidioides DNA as detected by PCR. Coccidioides antibody detection by lateral flow assay became negative after one year and decreased from 1:64 to 1:8 in the complement fixation test after two years. The (1 → 3)-ß-D-glucan levels normalised after two years without increase after cessation of antifungal therapy. Biomarkers in serum may guide treatment decisions in disseminated coccidioidomycosis.

Published
2020

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