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The patent application titled "Methods, Devices And System For Lawful Interception By Subscribing To A Notification" discusses the establishment and management of a Lawful Interception (LI) process in 5G networks. The invention aims to enable the utilization of LI system information for non-LI purposes, such as public safety monitoring, by introducing a Network Exposure Function (NEF) in LI standards. The patent application outlines methods performed by Lawful Interception Administration Function (LI ADMF), NEF, and Mediation and Delivery Function 2 (MDF2) devices to enhance investigation capabilities and reporting in LI systems. [Extracted from the article]

A patent application titled "Injector And Injection Method Therefor" was published online on November 14, 2024, by inventors from various locations in the United States and Canada. The application discusses the importance of vaccines in preventing infectious diseases and the limitations of traditional subcutaneous and intramuscular vaccination techniques. It introduces an auto-injector device designed to deliver vaccines into the epidermal and dermal tissues, potentially offering a more effective and less invasive vaccination method. The device aims to address issues such as needle anxiety, vaccine wastage, and the need for skilled healthcare professionals to administer vaccinations. [Extracted from the article]

The patent application discussed in the article focuses on antibodies capable of binding to the spike protein of SARS-CoV-2, the virus responsible for COVID-19. The inventors have identified 28 human monoclonal antibodies that show potent neutralization activity against various strains of SARS-CoV-2, including the Omicron variants. These antibodies have the potential for use in treating and preventing coronavirus infections, and the patent application outlines methods for producing, using, and administering these antibodies. [Extracted from the article]

A patent application has been filed for an apparatus and method designed to treat tooth decay, gum disease, and other medical conditions by eradicating oral pathogens and restoring oral microbiota balance. The device delivers a therapeutic fluid to the oral cavity, preventing the spread of pathogens into the bloodstream and reducing the risk of systemic infections and inflammation. The invention includes a mouthpiece with features such as a fluid diffuser array and biosensors to monitor oral health. [Extracted from the article]

A patent application for an "Antibacterial Fluid Dispensing And Temperature Scanning Device" has been filed by inventors from Canada and the United States. The device is designed to automate the dispensing of soap and antibacterial solutions while integrating features such as temperature scanning, UV sterilization, facial recognition, and pattern recognition. The device aims to provide touchless operation to prevent the transfer of bacteria, enhance cleanliness, and detect potential illnesses based on temperature readings. The patent application outlines various aspects of the device's design and functionality, including the use of sensors, displays, and dispensing mechanisms. [Extracted from the article]

A patent application for vaccine compositions to prevent coronavirus disease, specifically targeting SARS-CoV-2, was published online by inventors from various locations in the United States. The application highlights the urgent need for safe and effective vaccines to combat the global spread of COVID-19, caused by a novel coronavirus. The document outlines recombinant VSV vectors, particles, and immunogenic proteins as potential components of a SARS-CoV-2 vaccine, emphasizing the importance of developing large-scale manufacturing processes to induce protective immunity in vaccinated individuals. [Extracted from the article]

The patent application titled "Systems And Methods For Omics-Based Analysis Of Gene Expression" aims to provide enhanced methods for centralized access to diverse datasets and tools for comparative analysis in the context of infectious diseases research. The inventors developed methods for combining and reorganizing genomic and transcriptomic data into a searchable and interactive database, particularly focusing on pathogenic microorganisms. These methods involve determining homology, differential gene expression, and identifying virulence factors to facilitate the development of therapeutic agents. The patent application emphasizes the importance of understanding gene expression patterns in pathogenic microorganisms to inform treatment options and predict clinical outcomes. [Extracted from the article]

The patent application titled "Optoelectronic Device" by inventors CHEN, BO-JHIH, CHOU, MENG-SUNG, and WU, CHUNG-CHAN aims to address technical challenges in smart wearable products related to monitoring physiological signals accurately. The device includes components such as a light shielding layer, a mask, and a first light-transmissive component to improve accuracy and appearance. By concealing metal surfaces and minimizing stray light interference, the optoelectronic device enhances the functionality of smart wearable products for health monitoring. [Extracted from the article]

A patent application for "Inflatable Meditation Cushions And Methods" by inventor Emily Everett aims to address the increased importance of mindful health and wellness pursuits, such as yoga and meditation, in light of the mental health crisis and isolation experienced during the COVID-19 pandemic. The application describes methods for manufacturing and using inflatable meditation cushions, emphasizing the need for improved cushions that align with the contemplative purpose of meditation. The patent application focuses on creating cushions that are accessible, comfortable, and environmentally friendly, highlighting the benefits of incorporating sustainable practices in the production of meditation equipment. [Extracted from the article]

Researchers have submitted a patent application for a "Robotically Controlled Laser-Assisted Handpiece" designed to improve surgical bone resection procedures. The device aims to address issues related to cutting efficiency, cutting temperature, and tissue damage associated with current surgical instruments. By utilizing laser technology, the device offers a non-contact, athermal approach to bone resection, potentially enhancing surgical outcomes and patient recovery. [Extracted from the article]

A patent application titled "Inclusion Body Mediated Method For Double-Stranded RNA Producing" was published online by inventors Linfeng Huang and Panpan Huang. The technology described focuses on methods, insoluble complexes, and vectors for producing double-stranded RNA in bacterial cells, particularly Escherichia coli. This innovation aims to enhance the efficiency and diversity of double-stranded RNA production, potentially enabling more effective RNA interference applications in gene silencing and disease treatment. [Extracted from the article]

A patent application has been filed for the use of urolithins in treating long COVID-19 and symptoms associated with recovery from COVID-19. Urolithins have shown potential in improving various health conditions, including those related to inadequate mitochondrial activity. The inventors propose methods for administering urolithins to treat post-viral illnesses, such as chronic fatigue syndrome, triggered by viral infections like COVID-19. The patent application outlines the potential benefits of urolithins in enhancing muscle function and addressing symptoms like fatigue, headache, and joint pain. [Extracted from the article]

A patent application by inventors from Atlanta, GA, for a multiplexed electronic immunoassay using enzymatically amplified metallization on microparticles has been made available online. The technology aims to improve bead-based immunoassays by enhancing sensitivity, speed, and dynamic range while reducing the need for expensive optical instrumentation. The method involves selectively metalizing beads, measuring their electrical properties, and detecting biomarkers in biological samples, offering a potential solution for cost-effective and widespread diagnostic testing, especially for infectious diseases like COVID-19. [Extracted from the article]

The patent application discussed in the Medical Letter on the CDC & FDA focuses on the development of a SARS-CoV-2 test kit for RT-qPCR assays. The application highlights the importance of rapid diagnosis for the highly infectious disease, SARS-CoV-2, which emerged in Asia and led to a global pandemic. The kit includes specific primers and probes for detecting the virus, aiming to provide an efficient, sensitive, and reliable method for early diagnosis and surveillance of SARS-CoV-2. Additionally, the use of saliva samples as an alternative to nasopharyngeal swabs is suggested to reduce discomfort and the risk of transmission, making testing more accessible and appealing. [Extracted from the article]

Researchers have submitted a patent application for a method to detect viruses, including COVID-19, using Surface Enhanced Raman Spectroscopy (SERS) with peptide-modified nanostructured metal. The method aims to provide a quick, selective, and error-free way to detect viruses like SARS-CoV-2, addressing the need for adaptable diagnostic assays in the face of virus mutations. The patent application outlines the use of peptide-modified metal particles to capture and bind target viruses, enhancing Raman signals for detection. [Extracted from the article]

A patent application by Mordechai GURI describes a system and method for obtaining location data from mobile devices based on identifiers transmitted by these devices. The system involves deploying wireless transceivers in specific locations to collect signals from mobile devices, storing this data in a database, and analyzing it to identify user location and movement patterns. The technology aims to provide non-invasive and privacy-compliant methods for gathering location data in areas of interest, such as shopping malls, transportation centers, and traffic junctions, using machine learning and deep learning techniques. [Extracted from the article]

A patent application titled "Small Molecule Inhibitors of Formation of Neutrophil-Derived Extracellular Traps (NETosis) and Uses Thereof" was filed by inventors from Massachusetts and made available online on November 7, 2024. The application focuses on the regulation of NETosis by class I and IIb HDACs, offering potential therapeutic targets for conditions associated with NETosis, such as autoimmune diseases, cardiovascular conditions, inflammatory conditions, viral or bacterial infections, and cancer. The application also discusses the use of HDAC inhibitors in treating viral infections, including those caused by coronaviruses like SARS-CoV-2. [Extracted from the article]

The patent application titled "Systems And Methods Of Dynamically Presenting Datasets In A Graphical User Interface" by inventors HUANG, Vincent Chiu-Hua, SINGH, Preet Kanwal, and VIJ, Kanika, discusses data processes and audit operations for data records associated with entities, particularly in the banking sector. The application proposes systems and methods to dynamically recommend audit operations in response to changes in operational events, such as a pandemic or fluctuations in event data metrics. By utilizing event data and priority queues, the systems aim to identify and address operational event abnormalities in real-time or near real-time, enhancing the efficiency of audit processes. [Extracted from the article]

A patent application has been submitted for a patient proning device designed to assist in positioning intubated or immobilized patients to reduce morbidity from pulmonary diseases like acute respiratory distress syndrome (ARDS) or COVID-19. The device aims to decrease staffing requirements by providing a conformable structure with a shell that imparts an elliptical shape for rotation of the patient. It includes features such as inflatable chambers, tensioning belts, and low-friction interfaces to facilitate safe and effective patient positioning. [Extracted from the article]

A patent application by inventors from Singapore proposes a method to evaluate the risk of severe outcomes in infectious and inflammatory diseases, focusing on COVID-19 caused by SARS-CoV-2. The method involves measuring specific immune cell ratios in patient samples to identify those at higher risk of severe disease outcomes. The inventors also suggest potential treatments based on these measurements, such as cytokine storm inhibitors and COX inhibitors. This research aims to improve patient characterization and management in the context of the COVID-19 pandemic. [Extracted from the article]

A patent application has been submitted for a system that digitally reads lateral flow immunoassay (LFIA) diagnostic tests using mobile devices. This technology allows users to capture images of LFIA tests, analyze them using computer-based image processing, and interpret the results remotely. The system aims to enable accurate analysis and consultation by healthcare providers in non-clinical settings, offering potential benefits for population screening, clinical trials, and military testing. The patent application was filed by Ken Mayer and is available online for further reference. [Extracted from the article]

The patent application titled "Regulatory Composition of the Neuro-Immune-Endocrine and Cortisol Reducing System of the Human Being" discusses a composition of beta-glucans, silymarin, and prebiotics aimed at modulating the neuro-immune-endocrine axis to improve sleep quality and protect the liver and intestinal epithelium. The invention addresses the impact of exogenous and endogenous factors on sleep, highlighting the importance of maintaining a stable diet, good sleep quality, and moderate physical activity for longevity. The composition is designed to enhance emotional balance, immune system function, and endocrine regulation, contributing to overall health and well-being. [Extracted from the article]

A patent application titled "Structures Of Langya Virus Fusion Protein Ectodomain And Immunogenic Compositions Derived Therefrom" was filed by inventors Acharya and May, focusing on the newly identified Langya virus, a member of the Henipavirus genus. The patent application describes stabilizing mutations in the Langya virus fusion protein that can enhance its pre-fusion conformation, potentially leading to improved immunogens for vaccines against Henipaviruses. The research highlights the importance of understanding the structural determinants of Henipavirus glycoproteins for future therapeutic design and vaccine development. [Extracted from the article]

A patent application titled "Uses of Propranolol for Managing Viral Infections" was published online, highlighting the potential of propranolol in treating or preventing viral infections, including coronaviruses like SARS-CoV-2. Propranolol, traditionally known as a beta-blocker, has shown antiviral activity and may be administered in combination with other antiviral agents. The application emphasizes the need for improved therapies for viral infections and explores the use of propranolol in pharmaceutical compositions to address this need. [Extracted from the article]

A patent application titled "Therapeutic Compounds for Red Blood Cell-Mediated Delivery of an Active Pharmaceutical Ingredient to a Target Cell" was published online on October 31, 2024, by inventors from the US and South Korea. The application focuses on CD47, a protein involved in immune response regulation, and its potential as a therapeutic target for cancer, viral infections, and fibrotic diseases. The compounds described aim to inhibit CD47 activity and deliver active pharmaceutical ingredients to target cells, offering promise for cancer treatment. The patent application outlines various embodiments and claims related to the therapeutic compounds. [Extracted from the article]

A patent application by Charles Magee for a Coronavirus (Covid-19) Air Sanitization/Isolation System with Anti-Virus Curtain Walls has been made available online. The system aims to attract and destroy airborne droplets contaminated with the coronavirus using a saline and soap solution on anti-virus strips. It includes features such as magnets to prevent contact between strips, an air inlet housing with ventilation fans and filters, and UV light sources for disinfection. The system is designed to address the challenges of airborne virus transmission in enclosed spaces, particularly where social distancing is impractical. [Extracted from the article]

A patent application titled "Surgical Anastomosis Simulation Trainor" was published online by inventors from Canada and the United States. The application describes a kit for anastomoses simulation and training, including tubing for simulating bodily vessels and a method for manufacturing silicone tracheal or bronchial segments. The kit aims to provide innovative virtual technical skills education in response to changes in surgical education due to factors like the COVID-19 pandemic. The patent application emphasizes the use of rapid manufacturing methods and data processing for modern surgical training. [Extracted from the article]

A patent application by inventors from various locations was made available online for a method to quantify target nucleic acid loads across multiple samples, particularly for viral nucleic acids like SARS-CoV-2. The method involves amplifying target nucleic acids in test and control samples, generating standard curves, and determining absolute quantities using correction factors. This innovation aims to address challenges in detecting and monitoring pathogenic diseases by enabling comparisons of target nucleic acid loads in samples collected from sources like swabs, excluding blood samples. [Extracted from the article]

A patent application titled "Method And System For Measuring Cell-Mediated Immunity To Adeno-Associated-Virus Infection" was published online by inventors Ashokkumar and Sindhi. The application discusses the importance of measuring cell-mediated immunity in gene therapy using adeno-associated viruses (AAV) as vehicles. The method involves mixing white blood cells with viral antigens and measuring immune responses to assess the risk of immune reactions. This technology aims to enhance the management of immunosuppression after gene therapy and improve patient outcomes. [Extracted from the article]

A patent application for a therapeutic intubation device called the "Therapeutic Endotrachel System" has been submitted by inventor Matthew Corey. The device aims to treat compromised lung tissue, particularly in patients affected by COVID-19, by using ultraviolet-c (UVC) light emitting devices. The patent application outlines the components of the device, including probes, a controller, and specific features related to UVC light emission. This innovative device addresses the need for direct treatment of infected lung tissue, especially in the context of the COVID-19 pandemic. [Extracted from the article]

Researchers have submitted a patent application for a novel method of detecting nucleic acids in samples without the need for intensive preparation or amplification. This method allows for rapid and sensitive detection of target nucleic acids, including viral RNA, with high specificity. The inventors have developed a technique that involves excising and detecting specific target probes from the nucleic acids, enabling multiplexing and quantification of target nucleic acids in a sample. [Extracted from the article]

The patent application "Genetically Engineered Cell-Derived Vaccines" discusses the development of vaccines against infectious diseases, particularly focusing on coronaviruses like SARS-CoV-2. The application highlights the use of genetically engineered cells to express antigens and induce immune responses, aiming to create effective and targeted vaccines with reduced side effects. By utilizing cell-derived vesicles induced from engineered cells, the inventors propose a novel approach to vaccine development that could potentially address the challenges posed by emerging strains of viruses like SARS-CoV-2. [Extracted from the article]

The patent application by inventors from Japan focuses on developing a new carrier for purification to address issues like the spread of viruses and biotoxic substances. The application discusses the use of a nonwoven fabric base material comprising a mixed resin of polyolefin and a styrene-olefin copolymer for liquid purification. The inventors aim to provide an inexpensive, robust, and sterilization-resistant fiber material for liquid purification, emphasizing the reduction of fine particles and cleaning efforts. [Extracted from the article]

A patent application titled "Crispr-Based Protein Barcoding And Surface Assembly" by inventors BARBER, Karl W. and ELLEDGE, Stephen J. introduces Cas-containing fusion proteins and methods for their use. These fusion proteins can be utilized in protein microarrays for disease diagnostics and other biological applications. The invention aims to streamline the construction of protein libraries and overcome the labor and cost barriers associated with current protein display platforms. The patent application outlines various methods and compositions involving catalytically inactive Cas-related proteins, single guide RNAs (sgRNAs), and proteins of interest, offering a novel approach to large-scale protein studies. [Extracted from the article]

A patent application by inventors from Reykjavik, Iceland, describes an antimicrobial formulation containing free fatty acids (FFA) to inhibit microbial growth, particularly for treating viral respiratory infections like coronavirus. The FFA extract in the formulation is effective at concentrations ranging from 0.1% to 20% and can reduce microbial replication by up to 99.99%. The formulation can be administered orally, nasally, ocularly, or topically to prevent and treat infections caused by various viruses, including coronaviruses. [Extracted from the article]

The patent application "Protected Sample Collection Media" aims to address the need for reliable and contamination-free sample collection devices for testing viruses and pathogens. The inventors propose a sample collection media that can capture viruses and bacteria from exhalation airflow samples, minimizing contamination. The protected sample collection media includes a porous material covered by a protective sheath with a removable tab for easy handling, providing a simple and effective solution for sample collection and testing. [Extracted from the article]

A patent application for a "Toilet Sealing Device" was filed by inventor Hunt, Ryan from Saskatoon, CA, and made available online on October 17, 2024. The device aims to inhibit the movement of materials from inside a toilet bowl to outside, preventing unhygienic conditions and the transmission of diseases like COVID-19. It utilizes barriers and magnetic attraction to create seals between the toilet lid, seat, and bowl, ensuring a robust and effective system for maintaining cleanliness and hygiene in toilet use. The invention addresses the limitations of existing toilet-related devices and provides a simple yet efficient solution to prevent the spread of hazardous materials during toilet use. [Extracted from the article]

A patent application titled "Mask-Based Diagnostic Utilizing Ai Algorithms For Improved Patient Outcomes" by inventor John J. Daniels focuses on developing a diagnostic system using digital and analog devices to detect biomarkers of various diseases, including COVID-19 and cardiovascular conditions, from bodily fluids like exhaled breath. The system utilizes mask-based diagnostic (MBD) technology to collect and analyze biomarker data, incorporating artificial intelligence (AI) algorithms for pattern recognition and feedback to enhance patient outcomes. This innovative approach aims to enable remote monitoring of patients with cardiovascular disease and improve early detection and intervention strategies. [Extracted from the article]

A patent application titled "Ofatumumab For Treating Pediatric Ms" was published online, highlighting the high burden of pediatric multiple sclerosis (MS) on patients and their families. Current treatment options for pediatric MS are limited, leading to a significant unmet medical need. Ofatumumab, a monoclonal antibody targeting CD20, has shown promise in treating MS in adults and is now being explored for pediatric MS patients, offering potential benefits for this vulnerable population. The patent application outlines the potential use of ofatumumab in treating or preventing MS in pediatric patients with specific weight and age criteria, presenting a novel approach to addressing the challenges faced by this patient group. [Extracted from the article]

The patent application by John J. Daniels introduces a mask-based diagnostic system that utilizes AI algorithms to detect biomarkers of various diseases, including COVID-19 and cardiovascular conditions, from exhaled breath samples. The system aims to improve patient outcomes by enabling remote monitoring and early detection of physiological conditions through the analysis of biomarkers and biometric data. By collecting and analyzing data using machine learning algorithms and biosensors integrated into face masks, the system provides personalized alerts for healthcare interventions based on predicted likelihood of future cardiac events. [Extracted from the article]