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1. Researchers from Ann and Robert H. Lurie Children's Hospital of Chicago Discuss Research in Biliary Atresia (Single-cell sequencing of a novel model of neonatal bile duct ligation in mice identifies macrophage heterogeneity in obstructive...).

Subjects
BILIARY atresia, CHILDREN'S hospitals, BILE ducts, MACROPHAGES, CONNECTIVE tissue cells
Abstract

Keywords: Bile Duct Diseases and Conditions; Biliary Atresia; Biliary Tract Diseases and Conditions; Cholestasis; Connective Tissue Cells; Digestive System Abnormalities; Digestive System Diseases and Conditions; Gastroenterology; Health and Medicine; Histology; Immunology; Ligation; Macrophages; Mononuclear Phagocyte System; Myeloid Cells; Operative Surgical Procedures; Phagocytes; Surgery EN Bile Duct Diseases and Conditions Biliary Atresia Biliary Tract Diseases and Conditions Cholestasis Connective Tissue Cells Digestive System Abnormalities Digestive System Diseases and Conditions Gastroenterology Health and Medicine Histology Immunology Ligation Macrophages Mononuclear Phagocyte System Myeloid Cells Operative Surgical Procedures Phagocytes Surgery 630 630 1 09/19/23 20230924 NES 230924 2023 SEP 18 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Current study results on biliary atresia have been published. Neonatal BDL had significantly lower MHCII-Ly6c+ MPH versus murine BA, however, scRNA-seq identified greater etiology-specific MPH heterogeneity with increased endocytosis in neonatal BDL MPH versus cellular killing in murine BA MPH. [Extracted from the article]

Published
2023

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