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The article is devoted to the diverticular colon disease, its uncomplicated form, the connection with age. Symptoms allowing to define presence at this form of disease of IBS-like symptoms – pains and infringements of the psycho-emotional status are highlighted. The results of psychometric research and psychiatrist’s consultation of 102 patients are presented. The role of obesity in the genesis of diverticular disease is highlighted. The significance of spasmolytic therapy, in particular mebeverine, is presented.

The article gives information on the scope of ursodeoxycholic acid (UDCA). The most evident positive effects of therapy for cholelithiasis (SCI) and in primary biliary cirrhosis (PBC). The probability of using UDCA as a means of preventing CLS in cases of biliary sludge (SB) and in the risk group in elderly and elderly people is discussed. The data of our own study of the results of UDCA in 34 patients with non-alcoholic fatty liver disease, combined with the dyskinesia of the gallbladder (BL), BS and gastroesophageal reflux disease (GERD) are presented. Admission UDCA Grinterol demonstrated high clinical efficacy, safety and the absence of side effects.

Since 1980 when L. Ludwig et al. [1] identified changes in the liver characteristic of alcohol-induced hepatitis in persons who didn’t misuse alcohol, intense study of non-alcoholic fatty liver disease (NAFLD) started. The definition of NAFLD has two major principles: a morphological pattern in biopsy ma terial microscopy completely corresponds to changes induced by alcoholic pathology and the major etiologic factors is lacking – alcoholic at hepatotoxic dosages. Obligatory condition is to rule out viral, drug, metabolic and other reasons [2].

The article tells about the indications for use of ursodeoxycholic acid (UDCA). The most significant positive effects were demonstrated in primary biliary cirrhosis (PBC) and cholelithiasis (CL). The possibility of using UDCA for CL prophylaxis during biliary sludge (BS) and in risk groups -people of elderly and senile age - is discussed. The article presents the results of the authors’ study of UDCA administration in 32 patients with gallbladder deformity (GD) and BS. Grinterol (UDCA) demonstrated high clinical efficacy, safety and no side effects.