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The purpose of this paper is to evaluate the quality of life of children who have completed ALL treatment with respect to physical functioning as compared to healthy children of similar age. Materials and methods. The research was conducted among patients treated in the Chair and Clinic of Pediatrics, Hematology and Oncology of Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, who completed acute lymphoblastic leukemia treatment. It comprised children whose ALL treatment had finished at least 6 months prior to the research. The final group of patients who participated in the research consisted of 64 persons. Research referring to healthy children was carried out among students of primary schools, junior high schools and kindergartens throughout Bydgoszcz. Only children who had never undergone hospital treatment and did not suffer from chronic diseases were qualified for the said research. The comparative group included 70 healthy children. In order to evaluate the quality of life of children who had undergone ALL treatment and of healthy children James W. Varni’s standardized research instrument was used. Results. As far as children’s/adolescents’ subjective opinion is concerned, physical functioning was evaluated the lowest by adolescents aged 13-18. Pain and fatigue have a significant influence on lowering their quality of physical functioning. The highest evaluation of physical functioning was observed among patients aged 5-7. As far as indirect evaluation is concerned one can notice that physical functioning was evaluated the lowest by parents of children aged 13-18 and 2-4. While comparing physical functioning in both research groups major statistical differences in favour of the comparative group were noticed. Conclusion. The quality of life within the sphere of physical functioning of children and adolescents who have completed treatment is significantly lower than among healthy children.

Aim of the study . Assessment of malnutrition status in children with cancer during oncological treatment. Material and methods. 62 children aged from 0 to 18 years were included. Anthropometric and biochemical parameters were measured: weight (W), height(H), middle arm circumference (MAC), triceps skinfold thickness (TSFT), serum albumin. Middle arm muscle circumference (MAMC) was calculated. These variables were interpreted in accordance with Polish population percentiles charts and analyzed according AHOPCA 2004 Report. Adequately nourished- all criteria must be fulfilled: ideal body weight (IBW)≥90th percentile(ile), albumin>3,5 g/dL, weight loss 10%, TSFT and/or MAC less than 5th ile. Results. The prevalence of malnutrition at diagnosis ranged from several to nearly 50% children, depending upon the measurement used - in 22.6% of children by W, in 17.7% by H, in 19.4% by W/H ratio, in 21.0% by TSFT, in 32,3% by MAC, in 46,8% by MAMC. Hipoalbuminemia was noted in 29,0% of children. Weight loss >5% was detected in 29% of children, in 11% it was higher than 10%. At diagnosis about 37% of children were adequately nourished, 39% were depleted and 24% severely depleted. Finally, 66% of children were adequately nourished, but 14.5% had severe malnutrition in the final examination. Conclusions. Arm anthropometry is very useful for malnutrition detection and nutritional intervention.

A i m o f s t u d y. The assessment of nutritional status with a special attention towards overweight by anthropometric measurements and biochemical parameters of lipids in children with cancer. Ma t e r i a l a n d m e t h o d s. In a retrospective group data of 122 patients’ treatment history were analyzed. The patients were treated in our hospital in previous years and their weight and height were studied. In a prospective group 62 newly diagnosed children with cancer were examined. The additional anthropometric measurements were included in the research like skinfolds thickness and middle arm circumference and biochemical lipids date were taken. The data were analyzed three times: at the diagnosis, during the oncological treatment and after the intensive chemotherapy. R e s u l t s. In a retrospective group, after the oncological treatment the number of children with overweight increased: M/W>90 ile 6.6%, BMI >90 ile 6.6%, %IBW above 110% 25.5%, Cole’a index above 110% 21.3%, whereas the number of children with height > 90 ile decreased to 6.6%. At the beginning, in a prospective group the number of children with overweight was three times higher-11.3%. 26.2% patients had abnormal level of triglicerydes at diagnosis and 30.4% after treatment. Above 50% of patients had abnormal level of HDL cholesterol during the whole treatment. C o n c l u s i o n s. Children with cancer belong to the group of risk for obesity and hyperlipidemia during the oncological treatment and it may impact on treatment and outcomes and also have serious medical consequence to the health state in future. Głównym celem prowadzonych badań była ocena stanu odżywienia ze szczególnym uwzględnieniem parametrów antropometrycznych oraz stężenia lipidów u dzieci leczonych z powodu choroby nowotworowej. M a t e r i a ł i m e t o d y. Ocenie retrospektywnej poddano dane uzyskane podczas hospitalizacji 122 pacjentów leczonych w Klinice Pediatrii Hematologii i Onkologii Collegium Medicum Uniwersytetu Mikołaja Kopernika w Toruniu. Badanie poszerzono o ocenę prospektywną 62 dzieci z rozpoznaniem choroby nowotworowej. Badania antropometryczne obejmowały pomiar fału skórnego oraz obwód ramienia, a ponadto przeprowadzono ocenę parametrów lipidowych w momencie postawienia diagnozy, w trakcie leczenia onkologicznego oraz po zakończeniu intensywnej chemioterapii. Wy n i k i. W grupie poddanej ocenie retrospektywnej, po leczeniu onkologicznym liczba dzieci z nadwagą wzrosła: M/W> 90 percentyla – 6,6%, BMI> 90% percentyla – 6,6%, powyżej 110% ICC – 25,5%, współczynnik Cole'a powyżej 110% – 21,3%, podczas gdy liczba dzieci ze wzrostem > 90 percentyla zmniejszyła się do 6,6%. Na początku leczenia, w grupie ocenianej prospektywnie liczba dzieci z nadwagą była trzy razy wyższa i wyniosła 11,3%. U 26,2% pacjentów obserwowano nieprawidłowe stężenie trójglicerydów na początku badania i u 30,4% po leczeniu. Ponad 50% pacjentów miało nieprawidłowe stężenia cholesterolu HDL podczas całego leczenia. Wn i o s k i. Dzieci leczone z powodu choroby nowotworowej nalezą do grupy podwyższonego ryzyka otyłości i hiperlipemii w czasie leczenia onkologicznego, co może wpływać na leczenie i rokowanie nie tylko krótkoterminowe, ale także odległe.