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Objective: to evaluate the effectiveness of termination of pregnancy in the later stages of a combined method for congenital malformations of the fetus, incompatible with life. The prospective study involved 195 pregnant women, divided into two groups. The main group consisted of 98 women who underwent termination of pregnancy in the later periods by the following combined method. The comparison group included 97 women, abortion was carried out according to the WHO scheme. The effectiveness of the combined method of termination in late pregnancy in the main group was 99.0 % and 96.9 % in the comparison group.

A retrospective study of 76 pregnant HIV-positive women (main group) and 198 pregnant women without HIV infection (comparison group) with preterm birth and their newborns was conducted. In the main group, anemia, fetal growth retardation, meconium release into the amniotic fluid were most often recorded. Grade 1–2 cerebral ischemia was detected in 86.8 % of infants, respiratory failure in 7.9 %, while respiratory distress syndrome was prevented in 46 % of cases.