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1. Life-threatening rhabdomyolysis and Fanconi syndrome related to tenofovir disoproxil fumarate administration in an HIV-infected patient.

Author

Favarel-Garrigues, M., Hentzien, M., Berger, J.-L., Brunet, A., and Bani-Sadr, F.

Subjects
*FANCONI syndrome, *MULTIDRUG resistance-associated proteins, *DIABETES insipidus, *IMMUNE reconstitution inflammatory syndrome, *HYPONATREMIA
Abstract

We present the case of an HIV-infected patient who developed life-threatening rhabdomyolysis and Fanconi syndrome 11 years after initiation of TDF-based combination antiretroviral therapy (cART). Apart from our patient, the association of rhabdomyolysis and concomitant tubular nephropathy has been reported in three other patients in the literature [[5]]. The tubular nephropathy was diagnosed as Fanconi syndrome in two patients and acute tubular necrosis in the two other patients. [Extracted from the article]

Published
2020
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