513 results
Search Results
2. A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of actionElectronic supplementary information (ESI) available: All data supporting this study are included in the paper and provided as ESI accompanying this paper at the journal's website. See DOI: https://doi.org/10.1039/d2md00161f
3. Drugging the undruggable: a computational chemist's view of KRASG12CElectronic supplementary information (ESI) available: The ESI contains details of all simulations and protocols performed in this paper. See DOI: 10.1039/d1md00055a
4. Molecular understanding of the therapeutic potential of melanin inhibiting natural products
5. A concept of dual-responsive prodrugs based on oligomerization-controlled reactivity of ester groups: an improvement of cancer cells versusneutrophils selectivity of camptothecinElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00609c
6. Progress in small-molecule inhibitors targeting PD-L1
7. A practical synthesis of amino limonin/deoxylimonin derivatives as effective mitigators against inflammation and nociceptionElectronic supplementary information (ESI) available. See DOI: 10.1039/d0md00117a
8. Heterocyclic compounds as xanthine oxidase inhibitors for the management of hyperuricemia: synthetic strategies, structure–activity relationship and molecular docking studies (2018–2024)
9. The importance of tyrosines in multimers of cyclic RGD nonapeptides: towards αvβ6-integrin targeted radiotherapeuticsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d4md00073k
10. Unveiling sultam in drug discovery: spotlight on the underexplored scaffold
11. Design, synthesis, and structure–activity relationship studies of 6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole derivatives as necroptosis inhibitorsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d4md00265b
12. Research progress of metal–organic framework nanozymes in bacterial sensing, detection, and treatment
13. Discovery of new tricyclic spiroindole derivatives as potent P-glycoprotein inhibitors for reversing multidrug resistance enabled by a synthetic methodology-based libraryElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d4md00136b
14. Discovery of a new pyrido[2,3-d]pyridazine-2,8-dione derivative as a potential anti-inflammatory agent through COX-1/COX-2 dual inhibitionElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00604b
15. Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reactionElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00137g
16. Pharmacological overview of hederagenin and its derivatives
17. Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors
18. Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies
19. Inhibition of MARK4 by serotonin as an attractive therapeutic approach to combat Alzheimer's disease and neuroinflammationElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00053a
20. Synthesis and structure–activity relationships of pirfenidone derivatives as anti-fibrosis agents in vitroElectronic supplementary information (ESI) available: Synthetic procedures of compound 2–4and 1H and 13C NMR spectra of YZQ01–18. See DOI: https://doi.org/10.1039/d1md00403d
21. Correction: Design, synthesis and antimicrobial activity of usnic acid derivatives (MedChemComm (2018) 9 (870–882) DOI: 10.1039/C8MD00076J)
22. Design, synthesis and antimicrobial activity of usnic acid derivatives (vol 9, pg 870, 2019)
23. The development of HEC-866 and its analogues for the treatment of idiopathic pulmonary fibrosisElectronic supplementary information (ESI) available. See DOI: 10.1039/d1md00023c
24. Nitrile-containing pharmaceuticals: target, mechanism of action, and their SAR studies
25. Truncated S-MGBs: towards a parasite-specific and low aggregation chemotypeElectronic supplementary information (ESI) available. See DOI: 10.1039/d1md00110h
26. Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivoefficacy against visceral leishmaniasisElectronic supplementary information (ESI) available. See DOI: 10.1039/d0md00203h
27. Discovery of a novel kinase hinge binder fragment by dynamic undocking
28. Iridium piano stool complexes with activity against S. aureus and MRSA: it is past time to truly think outside of the box.
29. Design, synthesis and antimicrobial activity of usnic acid derivatives
30. Contents list.
31. Contents list.
32. Contents list.
33. Contents list.
34. Contents list.
35. Contents list.
36. Contents list.
37. Correction: Sustained anti-BCR–ABL activity with pH responsive imatinib mesylate loaded PCL nanoparticles in CML cells.
38. Contents list.
39. Contents list.
40. Contents list.
41. Contents list.
42. Navigating into the chemical space between MGCD0103 and SAHA: novel histone deacetylase inhibitors as a promising lead.
43. Contents list.
44. Contents list.
45. Contents list.
46. Contents list.
47. Contents list.
48. Contents list.
49. Contents list.
50. Contents list.
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.