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1. Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features

Author

Yannic C. Bartsch, Carolin Loos, Evan Rossignol, Jesse M. Fajnzylber, Dansu Yuan, Anchalee Avihingsanon, Sasiwimol Ubolyam, Thidarat Jupimai, Bernard Hirschel, Jintanat Ananworanich, Douglas A. Lauffenburger, Jonathan Z. Li, Galit Alter, and Boris Julg

Subjects
Microbiology, QR1-502
Abstract

Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation, have been identified as sensitive surrogates for disease activity in multiple diseases.

Published
2021
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