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The price V of a contingent claim in finance, insurance and economics is defined as an expectation of a stochastic expression. If the underlying uncertainty is modeled as a strong Markov process X, the Feynman–Kac theorem suggests that V is the unique solution of a boundary problem for a parabolic equation. In the case of PDO with constant symbols, simple probabilistic tools explained in this paper can be used to explicitly calculate expectations under very weak conditions on the process and study the regularity of the solution. Assuming that the Feynman–Kac theorem holds, and a more general boundary problem can be localized, the local results can be used to study the existence and regularity of solutions, and derive efficient numerical methods. In the paper, difficulties for the realization of this program are analyzed, several outstanding problems are listed, and several closely efficient methods are outlined. [ABSTRACT FROM AUTHOR]