1. Electrochemical & osteoblast adhesion study of engineered TiO2 nanotubular surfaces on titanium alloys.
- Author
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Rahman, Zia Ur, Haider, Waseem, Pompa, Luis, and Deen, K.M.
- Subjects
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ELECTROCHEMICAL sensors , *OSTEOBLASTS , *CELL adhesion , *TITANIUM dioxide , *TITANIUM alloys , *NANOTUBES - Abstract
TiO 2 nanotubes were grafted on the surface of cpTi, Ti6Al4V and Ti6Al4V-ELI with the aim to provide a new podium for human pre-osteoblast cell (MC3T3) adhesion and proliferation. The surface morphology and chemistry of these alloys were examined with scanning electron microscopy and energy dispersive x-ray spectroscopy. TiO 2 nanotubes were further characterized by cyclic potentiodynamic polarization tests and electrochemical impedance spectroscopy. The vertically aligned nanotubes were subjected to pre-osteoblast cell proliferation in order to better understand cell–material interaction. The study demonstrated that these cells interact differently with nanotubes of different titanium alloys. The significant acceleration in the growth rate of pre-osteoblast cell adhesion and proliferation is also witnessed. Additionally, the cytotoxicity of the leached metal ions was evaluated by using a tetrazolium-based bio-assay, MTS. Each group of data was operated for p < 0.05, concluded one way ANOVA to investigate the significance difference. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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