1. Synthesis of mesoporous hydroxyapatite via a vitamin C templating hydrothermal route
- Author
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Mengmeng Yang, Huan Zhou, Wenjie Wang, Ying Yang, and Yaping Bi
- Subjects
Pore size ,Solution composition ,Calcium hydroxide ,Materials science ,Vitamin C ,Mechanical Engineering ,Nanoparticle ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Hydrothermal circulation ,0104 chemical sciences ,chemistry.chemical_compound ,Adsorption ,chemistry ,Chemical engineering ,Mechanics of Materials ,General Materials Science ,0210 nano-technology ,Mesoporous material - Abstract
Mesoporous hydroxyapatite is widely applied in biomedical and environmental fields due to its high surface area and adsorption capacity. In current work a one-step hydrothermal method to synthesize mesoporous HA was developed with the assistance of a cost-effective template vitamin C. It was observed the pore size and morphology of hydrothermally synthesized HA were correlated to applied solution composition. A combination of calcium hydroxide, orthophosphate, and vitamin C can finally result in mesoporous rod-like HA nanoparticles with surface area of 88 m2.gā1 and pore size of 15.7 nm on average. The mesoporous HA exhibited enhanced adsorption of model drug doxorubicin in comparison to conventionally synthesized HA as expected. Consequently, this work provides new pathway to prepare mesoporous HA with advantages of economy and convenience.
- Published
- 2018
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