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The use of the porous Polylactic acid (PLA) for tissue engineering has gained the attention of the researchers worldwide. In this work, PLA tubes were extruded using CO 2 as a foaming agent. The foaming of the PLA tubes at various extruder screw rotational speed and different CO 2 pressure are studied in this work. Subsequently, morphological characterization and surface hydrophilicity studies of the tubes were carried out. It is be found that with an increase in the screw rpm, the contact angle first decreases and reaches the lowest value and then increase with the increase in screw rpm. Similarly, the effects of screw rpm and gas pressure on cross-sectional morphology and FTIR spectra were observed indicating an increase in crystallinity. [ABSTRACT FROM AUTHOR]