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The strength of tectonic deformation in tectonically complex regions, particularly multi-stage superimposed tectonic regions, can have a significant impact on shale gas preservation conditions. However, differential tectonic deformation has still not been quantitatively constrained, and its impact on the preservation conditions of shale gas is thus poorly understood in the northern Guizhou Province, southwest China. This study investigates the differential preservation conditions of marine shale gas in four eroded synclines (including Shixi, Daozhen, Zhongguan, and Fuyan Synclines) of the northern Guizhou Province. Interpretation of structures in field outcrops, geometry and kinematic analysis, and typical gas reservoir anatomy are combined to quantitatively explore the effect of superimposed deformation on the preservation conditions of shale gas. According to a set of new structural and kinematic constraints, the Riedel shear model for strike-slip faults is firstly conducted in the eroded synclines in the northern Guizhou Province, which innovatively established a linkage between detailed structural analysis and evaluation of shale-gas preservation conditions. We demonstrate that superimposing of deformations plays a role in differential accumulation in eroded synclines. The results indicate that (1) fault strike in the Shixi Syncline is more concentrated than Zhongguan and Fuyan Synclines, whereas fault strikes in the Zhongguan and Fuyan Synclines are more scattered. There is only one direction of maximum principal stress (σ 1) in the Shixi and Daozhen Synclines. There are two maximum principal stress directions (σ 1) in the Zhongguan and Fuyan Synclines. The Zhongguan and the Fuyan Synclines have tensional environments, whereas the Shixi and the Daozhen Syncline have compressional settings; (2) the formation dip angle, distance to a class II fracture, average detachment layer thickness, intensity of superimposed modifications, and interlimb angle may be positively correlated with gas content; (3) the progressive transformation pattern is established. These findings lay the foundation for the future research on the differential preservation mechanism of eroded synclines and may be useful for enhancing research on worldwide strike-slip faults controlling hydrocarbon accumulation. • Riedel shear model first adopted on shale-gas preservation in complex structure zone. • Superimposed deformation was clarified by new structural and kinematic constraints. • Differential shale-gas conceptual accumulation model on eroded synclines is built. • Strike-slip stepwise transformation model for shale-gas accumulation first stressed. [ABSTRACT FROM AUTHOR]