Search

The influence of Fenoterol administered to the upper and lower area of the air conducting system on antigen-induced bronchoconstriction was studied in 60 dogs. In small doses, Fenoterol administered to the upper airways blocked bronchoconstriction by antigen applied to upper but not to lower airways. The intravenous administration of the same dose was without effect. In large doses, Fenoterol blocked bronchoconstriction induced at both sites. Application of both doses of Fenoterol to lower airways blocked bronchoconstriction induced at both sites and was more effective than intravenous treatment. We concluded that there is an important local effect of Fenoterol on the upper respiratory tract in antigen-induced bronchoconstriction from this site as well as on the lower airways. [ABSTRACT FROM AUTHOR]

Copyright of Lung is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Lung is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)