1. Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective
- Author
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Trina Ekawati Tallei, Firzan Nainu, Abu Montakim Tareq, Jesus Simal-Gandara, Talha Bin Emran, Kuldeep Dhama, Saikat Mitra, Arka Jyoti Chakraborty, Donatella Cicia, Raffaele Capasso, Chakraborty, A. J., Mitra, S., Tallei, T. E., Tareq, A. M., Nainu, F., Cicia, D., Dhama, K., Emran, T. B., Simal-Gandara, J., and Capasso, R.
- Subjects
0301 basic medicine ,Bromelain (pharmacology) ,3309 Tecnología de Los Alimentos ,3209.04 Medicamentos Naturales ,Review ,Pharmacology ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,chemistry.chemical_compound ,Ananas comosu ,0302 clinical medicine ,Nanoparticle ,Medicine ,Ananas comosus ,lcsh:Science ,Ecology, Evolution, Behavior and Systematics ,Proteolytic enzymes ,Low toxicity ,Arthritis symptoms ,business.industry ,Pineapple ,Natural remedy ,Paleontology ,Antimicrobial ,Bioactive compound ,030104 developmental biology ,chemistry ,Space and Planetary Science ,030220 oncology & carcinogenesis ,lcsh:Q ,nanoparticles ,Bromelain ,business ,2302.09 Enzimología - Abstract
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most commonly used as an anti-inflammatory agent, though scientists have also discovered its potential as an anticancer and antimicrobial agent. It has been reported as having positive effects on the respiratory, digestive, and circulatory systems, and potentially on the immune system. It is a natural remedy for easing arthritis symptoms, including joint pain and stiffness. This review details bromelain’s varied uses in healthcare, its low toxicity, and its relationship to nanoparticles. The door of infinite possibilities will be opened up if further extensive research is carried out on this pineapple-derived enzyme.
- Published
- 2021