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Your search keyword '"Göhring, G"' showing total 22 results
Start Over Author "Göhring, G" Journal leukemia research
22 results on '"Göhring, G"'

1. P051 - Topic: AS04-MDS Biology and Pathogenesis/AS04d-Somatic mutations: THE EVOLVING GENETIC LANDSCAPE OF PEDIATRIC MDS-EB

Author

Erlacher, M., Yoshimi, A., Stasik, S., Ramamoorthy, S., Lebrecht, D., Noellke, P., Goehring, G., De Haas, V., Starý, J., Masetti, R., Ussowicz, M., Barzilai-Birenboim, S., De Moerloose, B., Kállay, K., Buechner, J., Dworzak, M., Catala, A., Hasle, H., Schmugge, M., Polychronopoulou, S., Boďová, I., Jahnukainen, K., Smith, O., Kavcic, M., Turkiewicz, D., Kjollerstrom, P., Locatelli, F., Wlodarski, M., Thiede, C., Strahm, B., and Niemeyer, C.

Published
2023
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2. P47 - Topic: AS07-Singular Entities/Subtypes/AS07c-Hereditary MDS including predisposition syndromes: HEMATOPOIETIC STEM CELL TRANSPLANTATION IN CHILDREN AND ADOLESCENTS WITH GATA2-RELATED MYELODYSPLASTIC SYNDROME

Author

Bortnick, R., Wlodarski, M., De Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Masetti, R., Stary, J., Turkiewicz, D., Ussowicz, M., Kozyra, E., Albert, M., Bader, P., Bordon, V., Cario, G., Beier, R., Schulte, J., Bresters, D., Mueller, I., Pichler, H., Sedlacek, P., Sauer, M., Zecca, M., Göhring, G., Yoshimi, A., Noellke, P., Erlacher, M., Locatelli, F., Niemeyer, C., and Strahm, B.

Published
2021
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3. O27 - Topic: AS06-Prognosis/AS06b-Predictive factors of response to treatment: OUTCOMES OF RELAPSED JUVENILE MYELOMONOCYTIC LEUKEMIA: THE ROLE OF SECOND HEMATOPOIETIC STEM CELL TRANSPLANTATION

Author

Yoshimi, A., Vinci, L., Flotho, C., Noellke, P., Erlacher, M., Lebrecht, D., Masetti, R., De Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Schmugge, M., Stary, J., Turkiewicz, D., Ussowicz, M., Catala, A., Buechner, J., Jahnukainen, K., Kállay, K., Fabri, O., Smith, O., Göhring, G., Locatelli, F., Strahm, B., and Niemeyer, C.

Published
2021
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4. O05 - Topic: AS04-MDS Biology and Pathogenesis/AS04b-Clonal diversity & evolution: SOMATIC GENETIC RESCUE IN SAMD9/SAMD9L MDS PREDISPOSITION SYNDROMES

Author

Sahoo, S., Pastor, V., Goodings, C., Noellke, P., Dworzak, M., Stary, J., Locatelli, F., Masetti, R., Schmugge, M., De Moerloose, B., Catala, A., Kállay, K., Turkiewicz, D., Hasle, H., Buechner, J., Jahnukainen, K., Ussowicz, M., Polychronopoulou, S., Smith, O., Fabri, O., Barzilai, S., De Haas, V., Baumann, I., Schwarz-Furlan, S., Göhring, G., Yoshimi, A., Flotho, C., Strahm, B., Erlacher, M., Niemeyer, C., and Wlodarski, M.

Published
2021
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5. Topic: AS07-Singular Entities/Subtypes/AS07c-Hereditary MDS including predisposition syndromes

Author

Bortnick, R., primary, Wlodarski, M., additional, De Haas, V., additional, De Moerloose, B., additional, Dworzak, M., additional, Hasle, H., additional, Masetti, R., additional, Stary, J., additional, Turkiewicz, D., additional, Ussowicz, M., additional, Kozyra, E., additional, Albert, M., additional, Bader, P., additional, Bordon, V., additional, Cario, G., additional, Beier, R., additional, Schulte, J., additional, Bresters, D., additional, Mueller, I., additional, Pichler, H., additional, Sedlacek, P., additional, Sauer, M., additional, Zecca, M., additional, Göhring, G., additional, Yoshimi, A., additional, Noellke, P., additional, Erlacher, M., additional, Locatelli, F., additional, Niemeyer, C., additional, and Strahm, B., additional

Published
2021
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6. Topic: AS06-Prognosis/AS06b-Predictive factors of response to treatment

Author

Yoshimi, A., primary, Vinci, L., additional, Flotho, C., additional, Noellke, P., additional, Erlacher, M., additional, Lebrecht, D., additional, Masetti, R., additional, De Haas, V., additional, De Moerloose, B., additional, Dworzak, M., additional, Hasle, H., additional, Schmugge, M., additional, Stary, J., additional, Turkiewicz, D., additional, Ussowicz, M., additional, Catala, A., additional, Buechner, J., additional, Jahnukainen, K., additional, Kállay, K., additional, Fabri, O., additional, Smith, O., additional, Göhring, G., additional, Locatelli, F., additional, Strahm, B., additional, and Niemeyer, C., additional

Published
2021
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7. Topic: AS04-MDS Biology and Pathogenesis/AS04b-Clonal diversity & evolution

Author

Sahoo, S., primary, Pastor, V., additional, Goodings, C., additional, Noellke, P., additional, Dworzak, M., additional, Stary, J., additional, Locatelli, F., additional, Masetti, R., additional, Schmugge, M., additional, De Moerloose, B., additional, Catala, A., additional, Kállay, K., additional, Turkiewicz, D., additional, Hasle, H., additional, Buechner, J., additional, Jahnukainen, K., additional, Ussowicz, M., additional, Polychronopoulou, S., additional, Smith, O., additional, Fabri, O., additional, Barzilai, S., additional, De Haas, V., additional, Baumann, I., additional, Schwarz-Furlan, S., additional, Göhring, G., additional, Yoshimi, A., additional, Flotho, C., additional, Strahm, B., additional, Erlacher, M., additional, Niemeyer, C., additional, and Wlodarski, M., additional

Published
2021
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9. P-211 Splicing gene mutations in MDS and secondary AML: Clinical implications in the setting of allogeneic hematopoietic stem cell transplantation

Author

Thol, F., primary, Koenecke, C., additional, Dobbernack, V., additional, Kade, S., additional, Huang, L., additional, Platzbecker, U., additional, Thiede, C., additional, Schroeder, T., additional, Kobbe, G., additional, Stadler, M., additional, Göhring, G., additional, Dammann, E., additional, Kleine, M., additional, Brauns, W., additional, Hallensleben, M., additional, Schlegelberger, B., additional, Krauter, J., additional, Ganser, A., additional, Kröger, N., additional, and Heuser, M., additional

Published
2013
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11. P-198 SPARC and TNF-α contribute significantly to erythroid failure in MDS with 5q deletion and influence considerably the efficacy of lenalidomide

Author

Buesche, G., primary, Giagounidis, A., additional, Bock, O., additional, Teoman, H., additional, Göhring, G., additional, Schlegelberger, B., additional, Dieck, S., additional, Ganser, A., additional, List, A., additional, Bennett, J.M., additional, Aul, C., additional, and Kreipe, H.H., additional

Published
2013
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13. O-003 ASXL1 frameshift mutations in patients with MDS and AML following MDS after allogeneic SCT: Update on 206 patients

Author

Koenecke, C., primary, Thol, F., additional, Löffeld, P., additional, Stadler, M., additional, Göhring, G., additional, Kleine, M., additional, Brauns, W., additional, Hallensleben, M., additional, Schlegelberger, B., additional, Krauter, J., additional, Kröger, N., additional, Ganser, A., additional, and Heuser, M., additional

Published
2013
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14. 68 ASXL1 is frequently mutated and associated with a negative prognosis in MDS

Author

Thol, F., primary, Friesen, I., additional, Damm, F., additional, Yun, H., additional, Weissinger, E.M., additional, Krauter, J., additional, Wagner, K., additional, Chaturvedi, A., additional, Sharma, A., additional, Wichmann, M., additional, Göhring, G., additional, Schumann, C., additional, Bug, G., additional, Ottmann, O., additional, Hofmann, W.-K., additional, Schlegelberger, B., additional, Heuser, M., additional, and Ganser, A., additional

Published
2011
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19. No evidence for ITSN1 loss in a patient with mental retardation and complex chromosomal rearrangements of 21q21-21q22.

Author

Ripperger T, Tauscher M, Thomay K, Göhring G, Kraemer D, Schlegelberger B, and Steinemann D

Subjects
Adult, Fatal Outcome, Gene Deletion, Humans, Intellectual Disability complications, Male, Myelodysplastic Syndromes complications, Myelodysplastic Syndromes genetics, Adaptor Proteins, Vesicular Transport genetics, Chromosome Aberrations, Chromosomes, Human, Pair 21 genetics, Intellectual Disability genetics
Published
2013
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20. Aberrant microRNA expression pattern in myelodysplastic bone marrow cells.

Author

Hussein K, Theophile K, Büsche G, Schlegelberger B, Göhring G, Kreipe H, and Bock O

Subjects
Adult, Aged, Aged, 80 and over, Base Sequence, Chromosome Deletion, DNA Primers, Female, Gene Expression Profiling, Humans, Karyotyping, Male, Middle Aged, Myelodysplastic Syndromes pathology, Polymerase Chain Reaction, MicroRNAs genetics, Myelodysplastic Syndromes genetics
Abstract

The microRNA/miR system might contribute to deregulation of cell homeostasis/disease phenotype. This is the first approach to generate an expression profile of 365 microRNAs in myelodysplastic syndromes (MDS) with normal karyotype (n=12) and distinct cytogenetic aberrations (n=12). In MDS-del(5q), a series of microRNAs not in the 5q-region was increased. MicroRNAs encoded on chromosomes 5, 7 and 8 were not differentially expressed in MDS with del(5q), -7 or +8. Evaluation in a larger cohort could confirm the up-regulation of the miR-1 in MDS. These findings provide evidence that MDS-haematopoiesis is distinct in its microRNA-expression pattern from non-neoplastic cells., (Copyright 2010 Elsevier Ltd. All rights reserved.)

Published
2010
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21. Recurrent involvement of heterochromatic regions in multiple myeloma-a multicolor FISH study.

Author

Lange K, Gadzicki D, Schlegelberger B, and Göhring G

Subjects
Adult, Aged, Aged, 80 and over, Female, Humans, Karyotyping, Male, Middle Aged, Multiple Myeloma pathology, Prognosis, Recurrence, Translocation, Genetic, Chromosome Aberrations, Chromosomes, Human genetics, In Situ Hybridization, Fluorescence, Multiple Myeloma genetics
Abstract

Chromosome aberrations are important prognostic markers in multiple myeloma (MM), but their identification may be hampered by complexity of the karyotypes. Using multicolor fluorescence in situ hybridization (mFISH), we found cryptic aberrations in 7 of 10 patients with a complex karyotype. Moreover, in addition to typical aberrations involving 1q, 13q, 14q and 17p and structural aberrations in chromosomes 1, 6, 9 and 19, (iso)dicentric chromosomes and whole-arm translocations were detected. These chromosome aberrations were generated by breaks in heterochromatic regions indicating an increased breakage of these regions, which may predispose to the generation of chromosome aberrations in multiple myeloma., (Copyright (c) 2010 Elsevier Ltd. All rights reserved.)

Published
2010
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22. Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome.

Author

Hussein K, Theophile K, Büsche G, Schlegelberger B, Göhring G, Kreipe H, and Bock O

Subjects
Aged, Chromosome Aberrations, Female, Gene Expression Profiling, Humans, Male, Microsatellite Repeats genetics, Myelodysplastic Syndromes metabolism, Oncogene Proteins v-myb biosynthesis, Proto-Oncogene Proteins c-kit biosynthesis, Gene Expression Regulation, Leukemic genetics, MicroRNAs genetics, Myelodysplastic Syndromes genetics
Abstract

We investigated whether, in myelodysplastic syndromes (MDS), aberrant expression of miR-150/miR-221/miR-222 and their designated target mRNA molecules MYB, p27 and c-KIT may be involved in insufficient haematopoiesis. In a series of MDS (n=52), an aberrant increase of miR-150 was found only in MDS with associated del(5q) (n=9; p<0.01). The mRNA expression of transcription factor MYB, the designated target of miR-150, was shown to correlate inversely with the miR-150 level. Acute leukaemia evolving from MDS (n=11) showed significantly decreased levels of miR-221 but not miR-222. We conclude that inhibition of proliferation via over-expressed miR-150 might contribute to myelodysplastic haematopoiesis in MDS-del(5q)., (Copyright (c) 2009 Elsevier Ltd. All rights reserved.)

Published
2010
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