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Your search keyword '"Wlodarska, Iwona"' showing total 14 results
Start Over Author "Wlodarska, Iwona" Journal leukemia & lymphoma
14 results on '"Wlodarska, Iwona"'

1. Detection of bone marrow involvement in newly diagnosed post-transplant lymphoproliferative disorder:18F-fluorodeoxyglucose positron emission tomography/computed tomographyversusbone marrow biopsy

Author

Gheysens, Olivier, primary, Thielemans, Sanne, additional, Morscio, Julie, additional, Boeckx, Nancy, additional, Goffin, Karolien E., additional, Deroose, Christophe M., additional, Sagaert, Xavier, additional, Wlodarska, Iwona, additional, Verhoef, Gregor, additional, Dierickx, Daan, additional, and Tousseyn, Thomas, additional

Published
2016
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2. Single-center analysis of biopsy-confirmed posttransplant lymphoproliferative disorder: incidence, clinicopathological characteristics and prognostic factors

Author

Dierickx, Daan, primary, Tousseyn, Thomas, additional, Sagaert, Xavier, additional, Fieuws, Steffen, additional, Wlodarska, Iwona, additional, Morscio, Julie, additional, Brepoels, Lieselot, additional, Kuypers, Dirk, additional, Vanhaecke, Johan, additional, Nevens, Frederik, additional, Verleden, Geert, additional, Van Damme-Lombaerts, Rita, additional, Renard, Marleen, additional, Pirenne, Jacques, additional, De Wolf-Peeters, Christiane, additional, and Verhoef, Gregor, additional

Published
2013
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3. Detection of bone marrow involvement in newly diagnosed post-transplant lymphoproliferative disorder: F-fluorodeoxyglucose positron emission tomography/computed tomography versus bone marrow biopsy.

Author

Gheysens, Olivier, Thielemans, Sanne, Morscio, Julie, Boeckx, Nancy, Goffin, Karolien E., Deroose, Christophe M., Sagaert, Xavier, Wlodarska, Iwona, Verhoef, Gregor, Dierickx, Daan, and Tousseyn, Thomas

Subjects
BONE marrow examination, BIOPSY, LYMPHOPROLIFERATIVE disorders, TRANSPLANTATION of organs, tissues, etc., POSITRON emission tomography
Abstract

Detecting bone marrow involvement (BMI) in lymphoma is important as it adversely affects stage. Bone marrow biopsy (BMB) remains the standard to detect BMI but is prone to sampling error. We retrospectively investigated whether18F-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG-PET/CT) could identify BMI in patients with post-transplant lymphoproliferative disorder (PTLD) with sufficient accuracy in comparison with staging BMB. Twenty-five patients diagnosed with PTLD who underwent18F-FDG-PET/CT and BMB within one month were evaluated. Based on our criteria, six patients (24%) were considered positive for BMI on18F-FDG-PET/CT compared to one by BMB. Although we cannot completely exclude false positive results on18F-FDG-PET/CT, our data indicate a significantly higher sensitivity of18F-FDG-PET/CT compared to BMB (100%vs17%) but similar specificity. These data confirm the high diagnostic performance of18F-FDG-PET/CT for detecting BMI, but prospective studies are needed to determine whether18F-FDG-PET/CT could indeed replace staging BMB in PTLD. [ABSTRACT FROM AUTHOR]

Published
2016
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4. Recurrent breakpoints in 14q32.13/TCL1Aregion in mature B-cell neoplasms with villous lymphocytes

Author

Urbankova, Helena, primary, Baens, Mathijs, additional, Michaux, Lucienne, additional, Tousseyn, Thomas, additional, Rack, Katrina, additional, Katrincsakova, Beata, additional, Ferreiro, Julio Finalet, additional, van Loo, Peter, additional, de Kelver, Wim, additional, Dierickx, Daan, additional, Demuynck, Hilde, additional, Delannoy, André, additional, Verschuere, Johan, additional, Jarošová, Marie, additional, de Wolf-Peeters, Chris, additional, Vandenberghe, Peter, additional, and Wlodarska, Iwona, additional

Published
2012
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11. Recurrent breakpoints in 14q32.13/ TCL1A region in mature B-cell neoplasms with villous lymphocytes.

Author

Urbankova, Helena, Baens, Mathijs, Michaux, Lucienne, Tousseyn, Thomas, Rack, Katrina, Katrincsakova, Beata, Ferreiro, Julio Finalet, van Loo, Peter, de Kelver, Wim, Dierickx, Daan, Demuynck, Hilde, Delannoy, André, Verschuere, Johan, Jarošová, Marie, de Wolf-Peeters, Chris, Vandenberghe, Peter, and Wlodarska, Iwona

Subjects
HORMONE-dependent tumors, B cell lymphoma, HUMAN chromosome abnormality diagnosis, GENETIC disorder diagnosis, GENETIC transcription regulation, DIAGNOSIS
Abstract

The genetic background of mature B-cell neoplasms with villous lymphocytes is poorly understood. We identified a novel breakpoint region at 14q32.13 that was rearranged together with IGH/14q32.33 in four cases of BRAF/V600E-negative leukemia/lymphoma with villous lymphocytes carrying either t(14;14)(q32.13;q32.33) (three patients) or del(14)(q32.13q32.33) (one patient). The 14q32.13 breakpoints were mapped by fluorescence in situ hybridization (FISH) in the region harboring the TCL1A/ TCL1B/ TCL6 genes, known to be affected by TCRA/ D-mediated t(14;14)(q11;q32)/inv(14)(q11q32) occurring in T-cell leukemia/lymphoma. To identify the target of t(14;14)(q32.13; q32.33) and del(14)(q32.13q32.33), quantitative real-time polymerase chain reaction (qRT-PCR) analysis of 25 candidate genes located centromerically and telomerically to the 14q32.13 breakpoint was performed. Any of the analyzed genes was commonly overexpressed in the presented cases. Of note, up-regulated transcription of TCL1A was observed in two cases. In summary, we provide evidence that IGH-mediated chromosomal aberrations affecting the 14q32.13/ TCL1A- TCL6 region are recurrent in mature B-cell neoplasms with villous lymphocytes. Despite extensive qRT-PCR studies, molecular consequences of these novel aberrations remain elusive. [ABSTRACT FROM AUTHOR]

Published
2012
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12. Chromosome 1p Abnormalities in B Non Hodgkin's Lymphoma

Author

van den Berghe, Elisabeth, primary, de Wolf-peeters, Chris, additional, Louwagie, Andries, additional, Thomas, JosÉ, additional, Wlodarska, Iwona, additional, Cin, Paola Dal, additional, Stul, Michel, additional, Cassiman, Jean-Jacques, additional, Mecucci, Cristina, additional, and van den Berghe, Herman, additional

Published
1991
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