41 results on '"Levine, R. A."'
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2. Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells
3. Effect of genetic profiling on prediction of therapeutic resistance and survival in adult acute myeloid leukemia
4. Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition
5. Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies
6. Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells
7. AKT is a therapeutic target in myeloproliferative neoplasms
8. Toll-like receptor alterations in myelodysplastic syndrome
9. miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation
10. Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia
11. The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity
12. NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
13. PHF6 mutations in adult acute myeloid leukemia
14. Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2
15. Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics
16. Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates
17. TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
18. Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
19. Systematic genomic screen for tyrosine kinase mutations in CLL
20. JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science
21. TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
22. Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia
23. KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32)
24. Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms
25. DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms
26. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
27. The most commonly reported variant in ASXL1 (c.1934dupG;p.Gly646TrpfsX12) is not a somatic alteration
28. IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
29. Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation
30. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the international working group for myelofibrosis research and treatment
31. Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias
32. Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells
33. Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies
34. miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation
35. Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia
36. The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity
37. NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
38. PHF6 mutations in adult acute myeloid leukemia
39. Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
40. KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32)
41. Dnmt3aregulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells
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