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1. Ultrahigh-Pressure Liquid Chromatography, Part III: Potential Issues.

Author

Dong, Michael W.

Subjects
*HIGH performance liquid chromatography, *TEMPERATURE effect, *INJECTORS, *FRICTION, *MACHINE performance, *INDUSTRIAL safety
Abstract

The article discusses the challenges in the use of ultrahigh-pressure liquid chromatography (UHPLC). Decriptions of the common issues encountered in UHPLC includes viscous heating which involves heating due to friction within the UHPLC column, quality of injector precision wherein partial-looping in the system was observed affecting the accuracy of the UHPLC, and safety issues due to the exposure of operators to high pressure environment.

Published
2017

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