15 results on '"Lievens, Yolande"'
Search Results
2. How public health services pay for radiotherapy in Europe: an ESTRO-HERO analysis of reimbursement.
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Lievens, Yolande, Defourny, Noémie, Corral, Julieta, Gasparotto, Chiara, Grau, Cai, Borras, Josep Maria, and ESTRO–HERO Consortium Collaborators
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PUBLIC health , *REIMBURSEMENT , *ONCOLOGISTS , *RADIOTHERAPY , *PRODUCTIVITY incentives , *CAPITAL investments - Abstract
Reimbursement is a key factor in defining which resources are made available to ensure quality, efficiency, availability, and access to specific health-care interventions. This Policy Review assesses publicly funded radiotherapy reimbursement systems in Europe. We did a survey of the national societies of radiation oncology in Europe, focusing on the general features and global structure of the reimbursement system, the coverage scope, and level for typical indications. The annual expenditure covering radiotherapy in each country was also collected. Most countries have a predominantly budgetary-based system. Variability was the major finding, both in the components of the treatment considered for reimbursement, and in the fees paid for specific treatment techniques, fractionations, and indications. Annual expenses for radiotherapy, including capital investment, available in 12 countries, represented between 4·3% and 12·3% (average 7·8%) of the cancer care budget. Although an essential pillar in multidisciplinary oncology, radiotherapy is an inexpensive modality with a modest contribution to total cancer care costs. Scientific societies and policy makers across Europe need to discuss new strategies for reimbursement, combining flexibility with incentives to improve productivity and quality, allowing radiation oncology services to follow evolving evidence. [ABSTRACT FROM AUTHOR]
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- 2020
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3. Characterisation and classification of oligometastatic disease: a European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer consensus recommendation.
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Guckenberger, Matthias, Lievens, Yolande, Bouma, Angelique B, Collette, Laurence, Dekker, Andre, deSouza, Nandita M, Dingemans, Anne-Marie C, Fournier, Beatrice, Hurkmans, Coen, Lecouvet, Frédéric E, Meattini, Icro, Romero, Alejandra Méndez, Ricardi, Umberto, Russell, Nicola S, Schanne, Daniel H, Scorsetti, Marta, Tombal, Bertrand, Verellen, Dirk, Verfaillie, Christine, and Ost, Piet
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NOSOLOGY , *CANCER treatment , *DELPHI method , *CANCER research , *DECISION trees - Abstract
Oligometastatic disease has been proposed as an intermediate state between localised and systemically metastasised disease. In the absence of randomised phase 3 trials, early clinical studies show improved survival when radical local therapy is added to standard systemic therapy for oligometastatic disease. However, since no biomarker for the identification of patients with true oligometastatic disease is clinically available, the diagnosis of oligometastatic disease is based solely on imaging findings. A small number of metastases on imaging could represent different clinical scenarios, which are associated with different prognoses and might require different treatment strategies. 20 international experts including 19 members of the European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer OligoCare project developed a comprehensive system for characterisation and classification of oligometastatic disease. We first did a systematic review of the literature to identify inclusion and exclusion criteria of prospective interventional oligometastatic disease clinical trials. Next, we used a Delphi consensus process to select a total of 17 oligometastatic disease characterisation factors that should be assessed in all patients treated with radical local therapy for oligometastatic disease, both within and outside of clinical trials. Using a second round of the Delphi method, we established a decision tree for oligometastatic disease classification together with a nomenclature. We agreed oligometastatic disease as the overall umbrella term. A history of polymetastatic disease before diagnosis of oligometastatic disease was used as the criterion to differentiate between induced oligometastatic disease (previous history of polymetastatic disease) and genuine oligometastatic disease (no history of polymetastatic disease). We further subclassified genuine oligometastatic disease into repeat oligometastatic disease (previous history of oligometastatic disease) and de-novo oligometastatic disease (first time diagnosis of oligometastatic disease). In de-novo oligometastatic disease, we differentiated between synchronous and metachronous oligometastatic disease. We did a final subclassification into oligorecurrence, oligoprogression, and oligopersistence, considering whether oligometastatic disease is diagnosed during a treatment-free interval or during active systemic therapy and whether or not an oligometastatic lesion is progressing on current imaging. This oligometastatic disease classification and nomenclature needs to be prospectively evaluated by the OligoCare study. [ABSTRACT FROM AUTHOR]
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- 2020
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4. Towards an evidence-informed value scale for surgical and radiation oncology: a multi-stakeholder perspective.
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Lievens, Yolande, Audisio, Riccardo, Banks, Ian, Collette, Laurence, Grau, Cai, Oliver, Kathy, Price, Richard, and Aggarwal, Ajay
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Surgery and radiotherapy, two locoregional cancer treatments, are essential to help improve cancer outcomes, control, and palliation. The continued evolution in treatment processes, techniques, and technologies-often at substantially increased costs-demands for direction on outcomes that are most valued by patients, and the evidence that is required before clinical adoption of these practices. Three recently introduced frameworks-the European Society for Medical Oncology Magnitude of Clinical Benefit Scale, the American Society of Clinical Oncology Value Framework, and the National Comprehensive Cancer Network Blocks-which all help define the value of oncology treatments, were appraised with a focus on their methods and definition of patient benefit. In this Review, we investigate the applicability of these frameworks to surgical and radiotherapy innovations. Findings show that these frameworks are not immediately transferable to locoregional cancer treatments. Moreover, the lack of emphasis on patient perspective and the reliance on traditional, trial-based endpoints such as survival, disease-free survival, and safety, calls for a new framework that includes real-world evidence with focus on the whole spectrum of patient-centred endpoints. Such an evidence-informed value scale would safeguard against the proliferation of low-value innovation while simultaneously increasing access to treatments that show significant improvements in the outcomes of cancer care. [ABSTRACT FROM AUTHOR]
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- 2019
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5. Radiotherapy capacity in Europe
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Grau, Cai, Borras, Josep M, Malicki, Julian, Slotman, Ben, Dunscombe, Peter, Coffey, Mary, Hollywood, Donal, Guedea, Ferran, Gasparotto, Chiara, and Lievens, Yolande
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- 2013
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6. ESMO-MCBS: setting the record straight - Authors' reply.
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Lievens, Yolande, Audisio, Riccardo, Banks, Ian, Collette, Laurence, Grau, Cai, Oliver, Kathy, Price, Richard, and Aggarwal, Ajay
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RECORDS , *AUTHORS , *ONCOLOGY , *RADIOTHERAPY , *TUMORS - Published
- 2019
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7. Metastases-directed stereotactic body radiotherapy in combination with targeted therapy or immunotherapy: systematic review and consensus recommendations by the EORTC–ESTRO OligoCare consortium.
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Kroeze, Stephanie G C, Pavic, Matea, Stellamans, Karin, Lievens, Yolande, Becherini, Carlotta, Scorsetti, Marta, Alongi, Filippo, Ricardi, Umberto, Jereczek-Fossa, Barbara Alicja, Westhoff, Paulien, But-Hadzic, Jasna, Widder, Joachim, Geets, Xavier, Bral, Samuel, Lambrecht, Maarten, Billiet, Charlotte, Sirak, Igor, Ramella, Sara, Giovanni Battista, Ivaldi, and Benavente, Sergi
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STEREOTACTIC radiotherapy , *CONSORTIA , *CONSENSUS (Social sciences) , *IMMUNOTHERAPY , *DELPHI method - Abstract
Stereotactic body radiotherapy (SBRT) for patients with metastatic cancer, especially when characterised by a low tumour burden (ie, oligometastatic disease), receiving targeted therapy or immunotherapy has become a frequently practised and guideline-supported treatment strategy. Despite the increasing use in routine clinical practice, there is little information on the safety of combining SBRT with modern targeted therapy or immunotherapy and a paucity of high-level evidence to guide clinical management. A systematic literature review was performed to identify the toxicity profiles of combined metastases-directed SBRT and targeted therapy or immunotherapy. These results served as the basis for an international Delphi consensus process among 28 interdisciplinary experts who are members of the European Society for Radiotherapy and Oncology (ESTRO) and European Organisation for Research and Treatment of Cancer (EORTC) OligoCare consortium. Consensus was sought about risk mitigation strategies of metastases-directed SBRT combined with targeted therapy or immunotherapy; a potential need for and length of interruption to targeted therapy or immunotherapy around SBRT delivery; and potential adaptations of radiation dose and fractionation. Results of this systematic review and consensus process compile the best available evidence for safe combination of metastases-directed SBRT and targeted therapy or immunotherapy for patients with metastatic or oligometastatic cancer and aim to guide today's clinical practice and the design of future clinical trials. [ABSTRACT FROM AUTHOR]
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- 2023
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8. European Groundshot-addressing Europe's cancer research challenges: a Lancet Oncology Commission.
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Lawler, Mark, Davies, Lynne, Oberst, Simon, Oliver, Kathy, Eggermont, Alexander, Schmutz, Anna, La Vecchia, Carlo, Allemani, Claudia, Lievens, Yolande, Naredi, Peter, Cufer, Tanja, Aggarwal, Ajay, Aapro, Matti, Apostolidis, Kathi, Baird, Anne-Marie, Cardoso, Fatima, Charalambous, Andreas, Coleman, Michel P, Costa, Alberto, and Crul, Mirjam
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CANCER research , *SERVICES for cancer patients , *SCIENTIFIC discoveries , *EARLY death , *COVID-19 pandemic - Abstract
Cancer research is a crucial pillar for countries to deliver more affordable, higher quality, and more equitable cancer care. Patients treated in research-active hospitals have better outcomes than patients who are not treated in these settings. However, cancer in Europe is at a crossroads. Cancer was already a leading cause of premature death before the COVID-19 pandemic, and the disastrous effects of the pandemic on early diagnosis and treatment will probably set back cancer outcomes in Europe by almost a decade. Recognising the pivotal importance of research not just to mitigate the pandemic today, but to build better European cancer services and systems for patients tomorrow, the Lancet Oncology European Groundshot Commission on cancer research brings together a wide range of experts, together with detailed new data on cancer research activity across Europe during the past 12 years. We have deployed this knowledge to help inform Europe's Beating Cancer Plan and the EU Cancer Mission, and to set out an evidence-driven, patient-centred cancer research roadmap for Europe. The high-resolution cancer research data we have generated show current activities, captured through different metrics, including by region, disease burden, research domain, and effect on outcomes. We have also included granular data on research collaboration, gender of researchers, and research funding. The inclusion of granular data has facilitated the identification of areas that are perhaps overemphasised in current cancer research in Europe, while also highlighting domains that are underserved. Our detailed data emphasise the need for more information-driven and data-driven cancer research strategies and planning going forward. A particular focus must be on central and eastern Europe, because our findings emphasise the widening gap in cancer research activity, and capacity and outcomes, compared with the rest of Europe. Citizens and patients, no matter where they are, must benefit from advances in cancer research. This Commission also highlights that the narrow focus on discovery science and biopharmaceutical research in Europe needs to be widened to include such areas as prevention and early diagnosis; treatment modalities such as radiotherapy and surgery; and a larger concentration on developing a research and innovation strategy for the 20 million Europeans living beyond a cancer diagnosis. Our data highlight the important role of comprehensive cancer centres in driving the European cancer research agenda. Crucial to a functioning cancer research strategy and its translation into patient benefit is the need for a greater emphasis on health policy and systems research, including implementation science, so that the innovative technological outputs from cancer research have a clear pathway to delivery. This European cancer research Commission has identified 12 key recommendations within a call to action to reimagine cancer research and its implementation in Europe. We hope this call to action will help to achieve our ambitious 70:35 target: 70% average survival for all European cancer patients by 2035. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Health service planning to assess the expected impact of centralising specialist cancer services on travel times, equity, and outcomes: a national population-based modelling study.
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Aggarwal, Ajay, Han, Lu, van der Geest, Stephanie, Lewis, Daniel, Lievens, Yolande, Borras, Josep, Jayne, David, Sullivan, Richard, Varkevisser, Marco, and van der Meulen, Jan
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HOSPITAL statistics , *TRAVEL time (Traffic engineering) , *RECTAL surgery , *HEALTH planning , *ONCOLOGISTS , *RECTAL cancer , *ONCOLOGIC surgery , *HOSPITALS , *TRAVEL , *MEDICAL care , *NATIONAL health services ,RECTUM tumors - Abstract
Background: Centralisation of specialist cancer services is occurring in many countries, often without evaluating the potential impact before implementation. We developed a health service planning model that can estimate the expected impacts of different centralisation scenarios on travel time, equity in access to services, patient outcomes, and hospital workload, using rectal cancer surgery as an example.Methods: For this population-based modelling study, we used routinely collected individual patient-level data from the National Cancer Registration and Analysis Service (NCRAS) and linked to the NHS Hospital Episode Statistics (HES) database for 11 888 patients who had been diagnosed with rectal cancer between April 1, 2016, and Dec 31, 2018, and who subsequently underwent a major rectal cancer resection in 163 National Health Service (NHS) hospitals providing rectal cancer surgery in England. Five centralisation scenarios were considered: closure of lower-volume centres (scenario A); closure of non-comprehensive cancer centres (scenario B); closure of centres with a net loss of patients to other centres (scenario C); closure of centres meeting all three criteria in scenarios A, B, and C (scenario D); and closure of centres with high readmission rates (scenario E). We used conditional logistic regression to predict probabilities of affected patients moving to each of the remaining centres and the expected changes in travel time, multilevel logistic regression to predict 30-day emergency readmission rates, and linear regression to analyse associations between the expected extra travel time for patients whose centre is closed and five patient characteristics, including age, sex, socioeconomic deprivation, comorbidity, and rurality of the patients' residential areas (rural, urban [non-London], or London). We also quantified additional workload, defined as the number of extra patients reallocated to remaining centres.Findings: Of the 11 888 patients, 4130 (34·7%) were women, 5249 (44·2%) were aged 70 years and older, and 5005 (42·1%) had at least one comorbidity. Scenario A resulted in closures of 43 (26%) of the 163 rectal cancer surgery centres, affecting 1599 (13·5%) patients; scenario B resulted in closures of 112 (69%) centres, affecting 7029 (59·1%) patients; scenario C resulted in closures of 56 (34%) centres, affecting 3142 (26·4%) patients; scenario D resulted in closures of 24 (15%) centres, affecting 874 (7·4%) patients; and scenario E resulted in closures of 16 (10%) centres, affecting 1000 (8·4%) patients. For each scenario, there was at least a two-times increase in predicted travel time for re-allocated patients with a mean increase in travel time of 23 min; however, the extra travel time did not disproportionately affect vulnerable patient groups. All scenarios resulted in significant reductions in 30-day readmission rates (range 4-48%). Three hospitals in scenario A, 41 hospitals in in scenario B, 13 hospitals in scenario C, no hospitals in scenario D, and two hospitals in scenario E had to manage at least 20 extra patients annually.Interpretation: This health service planning model can be used to to guide complex decisions about the closure of centres and inform mitigation strategies. The approach could be applied across different country or regional health-care systems for patients with cancer and other complex health conditons.Funding: National Institute for Health Research. [ABSTRACT FROM AUTHOR]- Published
- 2022
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10. Moonshot or groundshot: addressing Europe's cancer challenge through a patient-focused, data-enabled lens.
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Lawler, Mark, Naredi, Peter, Cufer, Tanja, Banks, Ian, Lievens, Yolande, Vassal, Giles, Aapro, Matti, Sotlar, Maja Južnič, Philip, Thierry, Jassem, Jacek, Pelouchova, Jana, Meunier, Françoise, Sullivan, Richard, and Lancet Oncology European Groundshot Commission
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- 2019
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11. Scale-up of radiotherapy for cervical cancer in the era of human papillomavirus vaccination in low-income and middle-income countries: a model-based analysis of need and economic impact.
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Rodin, Danielle, Burger, Emily A, Atun, Rifat, Barton, Michael, Gospodarowicz, Mary, Grover, Surbhi, Hanna, Timothy P, Jaffray, David A, Knaul, Felicia M, Lievens, Yolande, Zubizarreta, Eduardo, and Milosevic, Michael
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HUMAN papillomavirus vaccines , *ECONOMIC impact analysis , *LOW-income countries , *CERVIX uteri diseases , *MIDDLE-income countries , *CERVICAL cancer ,CERVIX uteri tumors - Abstract
Background: Radiotherapy is standard of care for cervical cancer, but major global gaps in access exist, particularly in low-income and middle-income countries. We modelled the health and economic benefits of a 20-year radiotherapy scale-up to estimate the long-term demand for treatment in the context of human papillomavirus (HPV) vaccination.Methods: We applied the Global Task Force on Radiotherapy for Cancer Control investment framework to model the health and economic benefits of scaling up external-beam radiotherapy and brachytherapy for cervical cancer in upper-middle-income, lower-middle-income, and low-income countries between 2015 and 2035. We estimated the unique costs of external-beam radiotherapy and brachytherapy and included a specific valuation of women's caregiving contributions. Model outcomes life-years gained and the human capital and full income net present value of investment. We estimated the effects of stage at diagnosis, radiotherapy delivery system, and simultaneous HPV vaccination (75% coverage) up to a time horizon set at 2072.Findings: For the period from 2015 to 2035, we estimated that 9·4 million women in low-income and middle-income countries required treatment with external-beam radiotherapy, of which 7·0 million also required treatment with brachytherapy. Incremental scale-up of radiotherapy in these countries from 2015 to meet optimal radiotherapy demand by 2035 yielded 11·4 million life-years gained, $59·3 billion in human capital net present value (-$1·5 billion in low-income, $19·9 billion in lower-middle-income, and $40·9 billion in upper-middle-income countries), and $151·5 billion in full income net present value ($1·5 billion in low-income countries, $53·6 billion in lower-middle-income countries, and $96·4 billion in upper-middle-income countries). Benefits increased with advanced stage of cervical cancer and more efficient scale up of radiotherapy. Bivalent HPV vaccination of 12-year-old girls resulted in a 3·9% reduction in incident cases from 2015-2035. By 2072, when the first vaccinated cohort of girls reaches 70 years of age, vaccination yielded a 22·9% reduction in cervical cancer incidence, with 38·4 million requiring external-beam radiotherapy and 28·8 million requiring brachytherapy.Interpretation: Effective cervical cancer control requires a comprehensive strategy. Even with HPV vaccination, radiotherapy treatment scale-up remains essential and produces large health benefits and a strong return on investment to countries at different levels of development.Funding: None. [ABSTRACT FROM AUTHOR]- Published
- 2019
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12. Use of modern imaging methods to facilitate trials of metastasis-directed therapy for oligometastatic disease in prostate cancer: a consensus recommendation from the EORTC Imaging Group.
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Lecouvet, Frédéric E, Oprea-Lager, Daniela E, Liu, Yan, Ost, Piet, Bidaut, Luc, Collette, Laurence, Deroose, Christophe M, Goffin, Karolien, Herrmann, Ken, Hoekstra, Otto S, Kramer, Gem, Lievens, Yolande, Lopci, Egesta, Pasquier, David, Petersen, Lars J, Talbot, Jean-Noël, Zacho, Helle, Tombal, Bertrand, and deSouza, Nandita M
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Oligometastatic disease represents a clinical and anatomical manifestation between localised and polymetastatic disease. In prostate cancer, as with other cancers, recognition of oligometastatic disease enables focal, metastasis-directed therapies. These therapies potentially shorten or postpone the use of systemic treatment and can delay further metastatic progression, thus increasing overall survival. Metastasis-directed therapies require imaging methods that definitively recognise oligometastatic disease to validate their efficacy and reliably monitor response, particularly so that morbidity associated with inappropriately treating disease subsequently recognised as polymetastatic can be avoided. In this Review, we assess imaging methods used to identify metastatic prostate cancer at first diagnosis, at biochemical recurrence, or at the castration-resistant stage. Standard imaging methods recommended by guidelines have insufficient diagnostic accuracy for reliably diagnosing oligometastatic disease. Modern imaging methods that use PET-CT with tumour-specific radiotracers (choline or prostate-specific membrane antigen ligand), and increasingly whole-body MRI with diffusion-weighted imaging, allow earlier and more precise identification of metastases. The European Organisation for Research and Treatment of Cancer (EORTC) Imaging Group suggests clinical algorithms to integrate modern imaging methods into the care pathway at the various stages of prostate cancer to identify oligometastatic disease. The EORTC proposes clinical trials that use modern imaging methods to evaluate the benefits of metastasis-directed therapies. [ABSTRACT FROM AUTHOR]
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- 2018
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13. Expanding global access to radiotherapy: the European Society for Radiotherapy and Oncology perspective.
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Poortmans, Philip, Valentini, Vincenzo, and Lievens, Yolande
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RADIOTHERAPY , *ONCOLOGY , *HOSPITAL radiological services , *MEDICAL electronics , *PHYSIOLOGICAL effects of radiation , *NATIONAL health services , *HEALTH services accessibility , *HEALTH status indicators , *MEDICAL care costs , *TUMORS , *WORLD health , *ECONOMICS ,DEVELOPING countries - Published
- 2015
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14. Expanding global access to radiotherapy.
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Atun, Rifat, Jaffray, David A, Barton, Michael B, Bray, Freddie, Baumann, Michael, Vikram, Bhadrasain, Hanna, Timothy P, Knaul, Felicia M, Lievens, Yolande, Lui, Tracey Y M, Milosevic, Michael, O'Sullivan, Brian, Rodin, Danielle L, Rosenblatt, Eduardo, Van Dyk, Jacob, Yap, Mei Ling, Zubizarreta, Eduardo, Gospodarowicz, Mary, and O'Sullivan, Brian
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RADIOTHERAPY , *CANCER treatment , *SYMPTOMS , *MEDICAL electronics , *PHYSIOLOGICAL effects of radiation , *TUMOR diagnosis , *COST effectiveness , *DIFFUSION of innovations , *FORECASTING , *HEALTH services accessibility , *HEALTH status indicators , *MEDICAL care costs , *NATIONAL health services , *TIME , *TUMORS , *WORLD health , *SOCIOECONOMIC factors , *TREATMENT effectiveness , *STATISTICAL models , *ECONOMICS ,DEVELOPING countries - Abstract
Radiotherapy is a critical and inseparable component of comprehensive cancer treatment and care. For many of the most common cancers in low-income and middle-income countries, radiotherapy is essential for effective treatment. In high-income countries, radiotherapy is used in more than half of all cases of cancer to cure localised disease, palliate symptoms, and control disease in incurable cancers. Yet, in planning and building treatment capacity for cancer, radiotherapy is frequently the last resource to be considered. Consequently, worldwide access to radiotherapy is unacceptably low. We present a new body of evidence that quantifies the worldwide coverage of radiotherapy services by country. We show the shortfall in access to radiotherapy by country and globally for 2015-35 based on current and projected need, and show substantial health and economic benefits to investing in radiotherapy. The cost of scaling up radiotherapy in the nominal model in 2015-35 is US$26·6 billion in low-income countries, $62·6 billion in lower-middle-income countries, and $94·8 billion in upper-middle-income countries, which amounts to $184·0 billion across all low-income and middle-income countries. In the efficiency model the costs were lower: $14·1 billion in low-income, $33·3 billion in lower-middle-income, and $49·4 billion in upper-middle-income countries-a total of $96·8 billion. Scale-up of radiotherapy capacity in 2015-35 from current levels could lead to saving of 26·9 million life-years in low-income and middle-income countries over the lifetime of the patients who received treatment. The economic benefits of investment in radiotherapy are very substantial. Using the nominal cost model could produce a net benefit of $278·1 billion in 2015-35 ($265·2 million in low-income countries, $38·5 billion in lower-middle-income countries, and $239·3 billion in upper-middle-income countries). Investment in the efficiency model would produce in the same period an even greater total benefit of $365·4 billion ($12·8 billion in low-income countries, $67·7 billion in lower-middle-income countries, and $284·7 billion in upper-middle-income countries). The returns, by the human-capital approach, are projected to be less with the nominal cost model, amounting to $16·9 billion in 2015-35 (-$14·9 billion in low-income countries; -$18·7 billion in lower-middle-income countries, and $50·5 billion in upper-middle-income countries). The returns with the efficiency model were projected to be greater, however, amounting to $104·2 billion (-$2·4 billion in low-income countries, $10·7 billion in lower-middle-income countries, and $95·9 billion in upper-middle-income countries). Our results provide compelling evidence that investment in radiotherapy not only enables treatment of large numbers of cancer cases to save lives, but also brings positive economic benefits. [ABSTRACT FROM AUTHOR]
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- 2015
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15. Global Task Force on Radiotherapy for Cancer Control.
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Jaffray, David A, Knaul, Felicia M, Atun, Rifat, Adams, Cary, Barton, Michael B, Baumann, Michael, Lievens, Yolande, Lui, Tracey Y M, Rodin, Danielle L, Rosenblatt, Eduardo, Torode, Julie, Van Dyk, Jacob, Vikram, Bhadrasain, and Gospodarowicz, Mary
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RADIOTHERAPY , *CANCER prevention , *NATIONAL health services , *HEALTH services accessibility , *HEALTH status indicators , *MEDICAL care costs , *TUMORS , *WORLD health , *ECONOMICS ,DEVELOPING countries - Published
- 2015
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