1. Acarbose-induced generalised erythema multiforme.
- Author
-
Kono T, Hayami M, Kobayashi H, Ishii M, and Taniguchi S
- Subjects
- Acarbose, Biopsy, Diabetes Mellitus, Type 2 pathology, Drug Eruptions pathology, Eosinophilia chemically induced, Eosinophilia pathology, Erythema Multiforme pathology, Humans, Hypoglycemic Agents therapeutic use, Male, Middle Aged, Skin drug effects, Skin pathology, Trisaccharides therapeutic use, Diabetes Mellitus, Type 2 drug therapy, Drug Eruptions diagnosis, Erythema Multiforme chemically induced, Hypoglycemic Agents adverse effects, Trisaccharides adverse effects
- Abstract
A 58-year-old man with diabetes mellitus was treated with acarbose 300 mg daily. 13 days after the start of treatment with acarbose, generalised erythema multiforme developed with blood eosinophilia. Tissue eosinophilia was also found histologically. A challenge test for acarbose confirmed allergic reaction clinically and histologically.
- Published
- 1999
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