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Opinion. States that dopamine receptors are abnormal or at least a useful therapeutic target in schizophrenia stemming from a traditional pharmacological and neurochemical approach. D2 receptor gene as a candidate gene approach; Danger of the candidate gene approach.

Reports on a large placebo-controlled study in France to measure the protective effect of vitamins and antioxidant minerals on mortality from cardio-vascular disease and cancer. Feasibility study on 1000 volunteers; Selection of 15,000 representatives of the French population; Dr. Serge Hercberg as coordinator.

Opinion. Presents the recommendation of the National Heart, Lung, and Blood Institute expert panel on the diagnosis and management of asthma that theophylline should not be used for acute attacks. Recommendation of the British Thoracic Society; Questions about the role of theophylline; Argument of those who abandoned theophylline; Salutary effects of theophylline.