1. Defining success in neoadjuvant breast cancer trials.
- Author
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Carey, Lisa A. and Winer, Eric P.
- Subjects
- *
ADJUVANT treatment of cancer , *POLYMERASE chain reaction , *BREAST cancer treatment , *CANCER chemotherapy , *DRUG efficacy - Abstract
The authors discuss the study by Patricia Cortazar and colleagues which examines the efficacy of neoadjuvant chemotherapy in breast cancer. The authors remark that the study failed to quantify the association between improvements in polymerase chain reaction (pCR) and either event-free survival or overall survival. The authors believe that the findings of the study need to be reassessed and different immediate endpoints need to be validated and developed.
- Published
- 2014
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