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Your search keyword '"G. Gahrton"' showing total 28 results
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28 results on '"G. Gahrton"'

1. [High-dose chemotherapy in breast cancer. Promising results in combination with stem cell support]

Author

P, Ljungman, B, Björkstrand, G, Gahrton, J, Nordenström, A, Shanwell, U, Glas, S, Rotstein, L E, Rutqvist, and N, Wilking

Subjects
Adult, Antineoplastic Combined Chemotherapy Protocols, Hematopoietic Stem Cell Transplantation, Humans, Antineoplastic Agents, Breast Neoplasms, Female, Middle Aged, Prognosis
Abstract

Thirty-three women with breast cancer have undergone high dose chemotherapy with autologous stem cell support at Huddinge Hospital. Twenty-eight patients had stage IV disease while five patients had disease stage II or III with involvement of10 axillary lymph nodes. Patients who received peripheral stem cells had a shorter duration of neutropenia than patients who received autologous bone marrow (p0.001). The transplant related mortality was 3 per cent. The calculated progression free survival was 39 per cent at 24 months after high dose therapy in women with stage IV chemosensitive breast cancer. Patients who got a complete remission after standard dose chemotherapy had a better survival rate than patients who got a partial remission. All women with refractory disease progressed within five months from therapy. Four out of five patients with disease stage II or III are progression free with the longest follow-up time of 46 months. High dose chemotherapy with stem cell support can be given with acceptable toxicity. The follow-up time is short but the results are promising, in particular for women who obtain a complete remission before the high dose therapy starts.

Published
1995

7. [Bone marrow transplantation at Huddinge Hospital: More and more successful therapy in malignant disease--the indications are gradually increasing]

Author

O, Ringdén, B, Lantz, P, Bolme, P, Ljungman, I, Båryd, G, Lundgren, G, Gahrton, B, Lönnqvist, C G, Groth, and E, Möller

Subjects
Adult, Sweden, Histiocytosis, Langerhans-Cell, Adolescent, Lymphoma, Leukemia, Myeloid, Primary Myelofibrosis, Anemia, Aplastic, Humans, Child, Multiple Myeloma, Bone Marrow Transplantation, Leukemia, Lymphoid
Published
1985

10. [Bone marrow transplantation]

Author

G, Gahrton, C G, Groth, G, Lundgren, and E, Möller

Subjects
Male, Anemia, Aplastic, Humans, Transplantation, Homologous, Middle Aged, Bone Marrow Transplantation
Published
1978

15. [High-dose chemotherapy in breast cancer. Promising results in combination with stem cell support].

Author

Ljungman P, Björkstrand B, Gahrton G, Nordenström J, Shanwell A, Glas U, Rotstein S, Rutqvist LE, and Wilking N

Subjects
Adult, Antineoplastic Agents adverse effects, Antineoplastic Combined Chemotherapy Protocols adverse effects, Breast Neoplasms immunology, Breast Neoplasms mortality, Female, Humans, Middle Aged, Prognosis, Antineoplastic Agents administration & dosage, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Breast Neoplasms drug therapy, Hematopoietic Stem Cell Transplantation adverse effects
Abstract

Thirty-three women with breast cancer have undergone high dose chemotherapy with autologous stem cell support at Huddinge Hospital. Twenty-eight patients had stage IV disease while five patients had disease stage II or III with involvement of > 10 axillary lymph nodes. Patients who received peripheral stem cells had a shorter duration of neutropenia than patients who received autologous bone marrow (p < 0.001). The transplant related mortality was 3 per cent. The calculated progression free survival was 39 per cent at 24 months after high dose therapy in women with stage IV chemosensitive breast cancer. Patients who got a complete remission after standard dose chemotherapy had a better survival rate than patients who got a partial remission. All women with refractory disease progressed within five months from therapy. Four out of five patients with disease stage II or III are progression free with the longest follow-up time of 46 months. High dose chemotherapy with stem cell support can be given with acceptable toxicity. The follow-up time is short but the results are promising, in particular for women who obtain a complete remission before the high dose therapy starts.

Published
1995

21. [Bone marrow transplantation at Huddinge Hospital: More and more successful therapy in malignant disease--the indications are gradually increasing].

Author

Ringdén O, Lantz B, Bolme P, Ljungman P, Båryd I, Lundgren G, Gahrton G, Lönnqvist B, Groth CG, and Möller E

Subjects
Adolescent, Adult, Anemia, Aplastic therapy, Child, Histiocytosis, Langerhans-Cell therapy, Humans, Leukemia, Lymphoid therapy, Leukemia, Myeloid therapy, Lymphoma therapy, Multiple Myeloma therapy, Primary Myelofibrosis therapy, Sweden, Bone Marrow Transplantation
Published
1985

22. [Bone marrow transplantation].

Author

Gahrton G, Groth CG, Lundgren G, and Möller E

Subjects
Humans, Male, Middle Aged, Transplantation, Homologous, Anemia, Aplastic therapy, Bone Marrow Transplantation
Published
1978

23. [Chronic myeloid leukemia--attempts at finding new methods of treatment].

Author

Gahrton G

Subjects
BCG Vaccine therapeutic use, Busulfan therapeutic use, Chromosome Aberrations, Chromosomes, Human, 21-22 and Y, Clone Cells, Female, Genetic Variation, Humans, Leukemia, Myeloid drug therapy, Leukemia, Myeloid genetics, Lymphocyte Activation, Male, Splenectomy, Translocation, Genetic, Leukemia, Myeloid therapy
Published
1975

26. [Multiple myeloma--pathophysiology and treatment].

Author

Gahrton G, Björkholm M, Mellstedt H, and Ost A

Subjects
Antineoplastic Agents therapeutic use, Bone Marrow Transplantation, Humans, Interferons therapeutic use, Prognosis, Multiple Myeloma physiopathology, Multiple Myeloma therapy
Published
1988

28. [Immunotherapy of leukemia--a realistic clinical possibility?].

Author

Gahrton G

Subjects
Antilymphocyte Serum therapeutic use, BCG Vaccine therapeutic use, Bone Marrow Cells, Bone Marrow Transplantation, Humans, Interferons therapeutic use, Leukemia, Lymphoid drug therapy, Leukemia, Lymphoid therapy, Leukemia, Myeloid, Acute therapy, Immunization, Passive, Immunotherapy, Leukemia therapy
Published
1971

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