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Total fatty acids and the proportions of methyl esters of individual fatty acids were measured in mouse milk. Pregnant mice were fed either a high fat (OF) diet or a low fat (LF) diet from 14 days of gestation. After parturition, each dam was milked once a day for a period of 18 days. The mean total fatty acid concentration over the entire study period was 110 mg/g of milk (approximately 11·7% fat as triglyceride) for both dietary treatment groups. During days 2 to 6 postpartum, the mean total fatty acid concentration for dams fed OF diet was lower than for the LF group. Although the concentration of total fatty acids of mouse milk was not affected by the level of dietary fat fed to the dam, several variations in the proportions of individual fatty acids were observed.

Summary Nephrocalcinosis was diagnosed as an incidental histopathological finding in 2 Sprague-Dawley rats of ISO g bodyweight, The calcified material was located along the entire corticomedullary junction. Dietary and other causes of nephrocalcinosis are discussed. Nephrocalcinosis is commonly found in older rats, but only infrequently reported in young ones, although the lesions have been seen in animals as young as 2-3 months of age (Casey, Ayers & Robinson, 1978; Paterson, 1979). This report describes the incidental finding of nephrocalcinosis in young Sprague-Dawley rats.