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Your search keyword '"Cunningham, Brian T."' showing total 11 results
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11 results on '"Cunningham, Brian T."'

5. External cavity laser biosensor

Author

Ge, Chun, primary, Lu, Meng, additional, George, Sherine, additional, Flood, Timothy A., additional, Wagner, Clark, additional, Zheng, Jie, additional, Pokhriyal, Anusha, additional, Eden, J. Gary, additional, Hergenrother, Paul J., additional, and Cunningham, Brian T., additional

Published
2013
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7. Label-free biodetection using a smartphone

Author

Gallegos, Dustin, primary, Long, Kenneth D., additional, Yu, Hojeong, additional, Clark, Peter P., additional, Lin, Yixiao, additional, George, Sherine, additional, Nath, Pabitra, additional, and Cunningham, Brian T., additional

Published
2013
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11. Biochemical sensor tubing for point-of-care monitoring of intravenous drugs and metabolites.

Author

Choi CJ, Wu HY, George S, Weyhenmeyer J, and Cunningham BT

Subjects
Humans, Nanoparticles chemistry, Pain drug therapy, Promethazine therapeutic use, Spectrum Analysis, Raman instrumentation, Biosensing Techniques instrumentation, Biosensing Techniques methods, Injections, Intravenous methods, Point-of-Care Systems standards
Abstract

In medical facilities, there is strong motivation to develop detection systems that can provide continuous analysis of fluids in medical tubing used to either deliver or remove fluids from a patient's body. Possible applications include systems that increase the safety of intravenous (IV) drug injection and point-of-care health monitoring. In this work, we incorporated a surface-enhanced Raman scattering (SERS) sensor comprised of an array of closely spaced metal nanodomes into flexible tubing commonly used for IV drug delivery and urinary catheters. The nanodome sensor was fabricated by a low-cost, large-area process that enables single use disposable operation. As exemplary demonstrations, the sensor was used to kinetically detect promethazine (pain medication) and urea (urinary metabolite) within their clinically relevant concentration ranges. Distinct SERS peaks for each analyte were used to demonstrate separate detection and co-detection of the analytes.

Published
2012
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