1. The Parathyroid carcinoma: a diagnostic challenge before surgery
- Author
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Baïdy Sy, Kane, Maïmouna, Sow, Nafissatou, Diagne, Nfally, Badji, Mamadou, Seck, Geraud, Akpo, Awa, Cheikh Ndao, Boundia, Djiba, Atoumane, Faye, Souhaïbou, Ndongo, and Abdoulaye, Pouye
- Subjects
Adult ,Diagnosis, Differential ,Parathyroidectomy ,Parathyroid Neoplasms ,Parathyroid Hormone ,Carcinoma ,Preoperative Care ,Hypercalcemia ,Humans ,Neck Dissection ,Female ,Hyperparathyroidism, Primary ,Senegal - Abstract
Parathroid Carcinoma is a rare cause of primary hyperparathyroidism (PPH). His diagnosis is a real challenge. We report an observation and discuss the diagnostic guidelines before surgery.A 31-year-old Senegalese woman was admitted to our department for the exploration of diffuse bone pain and multiple pathological fractures. Physical examination revealed a right lateral mass of the neck. Serum calcium level was 142.2 mg / l and serum parathyroid hormone 42 N. Ultrasound and cervical tomodensitometry showed a parathyroid mass compressing the thyroid and trachea. The extension assessment revealed osteolytic lesions and T4-T5 epiduritis evoking metastases. Surgery and histology were performed. According to the histopathology and clinical context, the tumor was identified as a parathyroid carcinoma.The preoperative evaluation of a patient with severe hypercalcemia and high PTH levels should include the possible diagnosis of parathyroid carcinoma, especially in symptomatic patients or in case of palpable neck mass.
- Published
- 2019