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2. Hémorragies cérébro-méningées sur ruptures d’anévrismes inaugurales d’une vascularite cérébrale lupique

Author

Jérôme Franques, N. Jourde, F. Chapon, S. Brah, Laurent Chiche, G. Thomas, J.M. Durand, Rodolphe Jean, and Jean-Robert Harlé

Subjects
Gastroenterology, Internal Medicine
Abstract

Resume Les anevrismes cerebraux secondaires a la vascularite lupique sont rares. Nous rapportons l’observation d’une patiente hospitalisee pour poussee lupique avec convulsions inaugurales. L’angioscanner revelait une hemorragie sous-arachnoidienne par rupture d’un anevrisme de l’artere cerebelleuse superieure. La patiente presentait apres plusieurs jours, et malgre un traitement associant corticoides et cyclophosphamide, une seconde hemorragie sur rupture d’un nouvel anevrisme au niveau des arteres lenticulo-striees, dont l’issue a ete fatale. Nous discutons ensuite de la frequence et de la prise en charge de cette complication severe du lupus erythemateux systemique.

Published
2012
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3. [Geophagy associated with severe anemia in non-pregnant women: A case series of 12 patients]

Author

E, Adehossi, B, Malam-Abdou, A, Andia, A, Djibrilla, S, Sani Beydou, S, Brah, M, Daou, and L, Chiche

Subjects
Adult, Cohort Studies, Hospitalization, Young Adult, Adolescent, Pica, Humans, Anemia, Female, Severity of Illness Index
Abstract

Geophagy or soil eating is mostly described in pregnant women from Sub-Saharan Africa, South America. Here, we report 12 cases of geophagy associated with severe anemia in non-pregnant Nigerian women.The median age at diagnosis was 34.5 years. The socioeconomic level was average for all patients. The median hemoglobin level at admission was 6.9g/dL (3.3-8.6), median corpuscular volume was 78.3fL (63-106) and median serum ferritin was 9.2ng/mL (3.6-11.2). The reasons of this practice were "desire" (5/12) and tradition (4/12). All patients received psychotherapy and supplementation with intravenous iron.Geophagy is an underestimated practice in developed countries and in non-pregnant women. It can be the cause of severe iron deficiency and must be discussed in patients with anemia, including non-pregnant patients, and in Africa as well as in migration areas, where the practice can be exported.

Published
2015

5. [Subarachnoid hemorrhages form ruptured aneurysms as the presenting feature of lupus cerebral vasculitis]

Author

S, Brah, G, Thomas, F, Chapon, J, Franques, N, Jourde, J-R, Harlé, J-M, Durand, R, Jean, and L, Chiche

Subjects
Adult, Fatal Outcome, Rupture, Spontaneous, Seizures, Lupus Vasculitis, Central Nervous System, Humans, Female, Intracranial Aneurysm, Aneurysm, Ruptured, Subarachnoid Hemorrhage, Magnetic Resonance Imaging, Cerebral Angiography
Abstract

Cerebral aneurysms secondary to cerebral vasculitis related to systemic lupus erythematosus are rare. We report a 31-year-old woman who presented with a lupus flare associated with inaugural generalized seizures. Computed tomography angiography showed subarachnoid hemorrhage by rupture of a cerebellar artery fusiform aneurysm. Later, despite the initiation of corticosteroids and cyclophosphamide, she presented a second cerebral hemorrhage due to the rupture of a new aneurysm in lenticulostriates arteries. The outcome was fatal. We discuss the frequency and management of this severe complication of systemic lupus erythematosus.

Published
2010

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