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These 2 cases were similar in terms of the time of onset of problems at the 8th month, the clinical and radiological signs of the tumour, and the existence of an amenorrhoea-galactorrhoea syndrome with hyperprolactinaemia. They differed with regard to the mode in which the pregnancy was obtained: one was induced by anti-prolactins in the presence of a normal sella turcica whilst the other began during the cycle following the administration of clomiphene with no prior radiological study of the sella turcica. They also differed in terms of the course: intra-tumoural haematoma requiring early surgery in one, hyperplasia and oedema regressing after delivery in the other making it possible to avoid immediate treatment.

A case of pregnancy in a patient with trisomy 21 with birth of a hypotrophic infant, with a normal caryotype but multiple malformations. This case illustrates the limitations on antenatal diagnosis by amniocentesis. Study of the literature confirms the unfavourable foetal prognosis as a result of the risk of transmission of the chromosomal abnormality and, secondly, the prevalence of incest.