27 results on '"Jung-Eun Cheon"'
Search Results
2. Deep Learning-Based Computed Tomography Image Standardization to Improve Generalizability of Deep Learning-Based Hepatic Segmentation.
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Seul Bi Lee, Youngtaek Hong, Yeon Jin Cho, Dawun Jeong, Jina Lee, Soon Ho Yoon, Seunghyun Lee, Young Hun Choi, and Jung-Eun Cheon
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- 2023
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3. Posterior Lung Herniation in Pulmonary Agenesis and Aplasia: Chest Radiograph and Cross-Sectional Imaging Correlation
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Woo Sun Kim, Bo Kyung Je, Ji Eun Park, Young Jin Ryu, Ji Young Kim, Young Hun Choi, Kyung Soo Lee, and Jung Eun Cheon
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Lung Diseases ,Male ,Chest radiography ,Pulmonary aplasia ,medicine.artery ,medicine ,Thoracic aorta ,Humans ,Radiology, Nuclear Medicine and imaging ,Abnormalities, Multiple ,Posterior lung herniation ,Child ,Lung ,Bronchus ,Aorta ,medicine.diagnostic_test ,business.industry ,Pulmonary Agenesis ,Infant ,Aplasia ,Anatomy ,Pediatric Imaging ,respiratory system ,Brief Research Report ,medicine.disease ,respiratory tract diseases ,medicine.anatomical_structure ,Descending aorta ,Female ,Pulmonary agenesis ,business ,Chest radiograph ,Tomography, X-Ray Computed ,CT - Abstract
Objective To describe the anatomic locations and imaging features of posterior lung herniation in unilateral pulmonary agenesis and aplasia, focusing on radiograph-CT/MRI correlation. Materials and methods A total of 10 patients (seven with pulmonary agenesis and three with pulmonary aplasia, male: female = 1:9, mean age 7.3 years, age range from 1 month to 20 years) were included. Chest radiographs (n = 9), CT (n = 9), and MRI (n = 1) were reviewed to assess the type of lung underdevelopment, presence of anterior and posterior lung herniation, bronchus origin, supplying artery, and draining vein of the herniated lung. Results Pulmonary agenesis/aplasia more commonly affected the left lung (n = 7) than the right lung (n = 3). Anterior lung herniation was observed in nine of the 10 patients. Posterior lung herniation was observed in seven patients with left pulmonary agenesis/aplasia. Two patients showed posterior lung herniation crossing the midline but not beyond the aorta, and five patients showed the posteriorly herniated right lower lobe crossing the midline to extend into the left hemithorax farther beyond the descending thoracic aorta through the space between the esophagus and the aorta. This anatomical configuration resulted in a characteristic radiographic finding of a radiolucent area with a convex lateral border and a vertical medial border in the left lower lung zone, revealing a tongue-like projection on CT and MRI. Conclusion Posterior lung herniation occurs in unilateral left lung agenesis/aplasia. Approximately 70% of the cases of posterior lung herniation reveal a unique radiolucent tongue-like projection in the left lower lung zone on imaging studies, which is caused by the extension of the posteriorly herniated right lung farther beyond the descending aorta.
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- 2021
4. Deep Learning-Assisted Diagnosis of Pediatric Skull Fractures on Plain Radiographs
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Jae Won Choi, Yeon Jin Cho, Ji Young Ha, Yun Young Lee, Seok Young Koh, June Young Seo, Young Hun Choi, Jung-Eun Cheon, Ji Hoon Phi, Injoon Kim, Jaekwang Yang, and Woo Sun Kim
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Radiography ,Deep Learning ,Skull Fractures ,Artificial Intelligence ,Skull ,Humans ,Radiographic Image Interpretation, Computer-Assisted ,Radiology, Nuclear Medicine and imaging ,Child ,Sensitivity and Specificity ,Retrospective Studies - Abstract
To develop and evaluate a deep learning-based artificial intelligence (AI) model for detecting skull fractures on plain radiographs in children.This retrospective multi-center study consisted of a development dataset acquired from two hospitals (n = 149 and 264) and an external test set (n = 95) from a third hospital. Datasets included children with head trauma who underwent both skull radiography and cranial computed tomography (CT). The development dataset was split into training, tuning, and internal test sets in a ratio of 7:1:2. The reference standard for skull fracture was cranial CT. Two radiology residents, a pediatric radiologist, and two emergency physicians participated in a two-session observer study on an external test set with and without AI assistance. We obtained the area under the receiver operating characteristic curve (AUROC), sensitivity, and specificity along with their 95% confidence intervals (CIs).The AI model showed an AUROC of 0.922 (95% CI, 0.842-0.969) in the internal test set and 0.870 (95% CI, 0.785-0.930) in the external test set. The model had a sensitivity of 81.1% (95% CI, 64.8%-92.0%) and specificity of 91.3% (95% CI, 79.2%-97.6%) for the internal test set and 78.9% (95% CI, 54.4%-93.9%) and 88.2% (95% CI, 78.7%-94.4%), respectively, for the external test set. With the model's assistance, significant AUROC improvement was observed in radiology residents (pooled results) and emergency physicians (pooled results) with the difference from reading without AI assistance of 0.094 (95% CI, 0.020-0.168;A deep learning-based AI model improved the performance of inexperienced radiologists and emergency physicians in diagnosing pediatric skull fractures on plain radiographs.
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- 2022
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5. Posterior Lung Herniation in Pulmonary Agenesis and Aplasia: Chest Radiograph and Cross-Sectional Imaging Correlation.
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Ji Young Kim, Woo Sun Kim, Kyung Soo Lee, Bo-Kyung Je, Ji Eun Park, Young Jin Ryu, Young Hun Choi, and Jung-Eun Cheon
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- 2021
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6. Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
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Young Hun Choi, Se Woo Kim, Yeon Jin Cho, Seunghyun Lee, Hyoung Suk Park, Young Jin Ryu, Seul Bi Lee, Woo Sun Kim, Jung Eun Cheon, Gayoung Choi, Kiwan Jeon, and Jae-Yeon Hwang
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musculoskeletal diseases ,Artificial intelligence ,Radiography ,education ,Sensitivity and Specificity ,Convolutional neural network ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Child ,Retrospective Studies ,Hip dysplasia ,Receiver operating characteristic ,business.industry ,Developmental dysplasia ,Deep learning ,Significant difference ,Infant ,Pediatric Imaging ,medicine.disease ,Pediatric Radiology ,ROC Curve ,Area Under Curve ,030220 oncology & carcinogenesis ,Developmental Dysplasia of the Hip ,Original Article ,business ,Algorithm ,Algorithms - Abstract
Objective To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. Materials and Methods Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to construct a dataset that was further divided into training (80%), validation (10%), or test sets (10%). Three radiologists were asked to label the hip images as normal or DDH. To investigate the diagnostic performance of the deep learning algorithm, we calculated the receiver operating characteristics (ROC), precision-recall curve (PRC) plots, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) and compared them with the performance of radiologists with different levels of experience. Results The area under the ROC plot generated by the deep learning algorithm and radiologists was 0.988 and 0.988–0.919, respectively. The area under the PRC plot generated by the deep learning algorithm and radiologists was 0.973 and 0.618–0.958, respectively. The sensitivity, specificity, PPV, and NPV of the proposed deep learning algorithm were 98.0, 98.1, 84.5, and 99.8%, respectively. There was no significant difference in the diagnosis of DDH by the algorithm and the radiologist with experience in pediatric radiology (p = 0.180). However, the proposed model showed higher sensitivity, specificity, and PPV, compared to the radiologist without experience in pediatric radiology (p < 0.001). Conclusion The proposed deep learning algorithm provided an accurate diagnosis of DDH on hip radiographs, which was comparable to the diagnosis by an experienced radiologist.
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- 2021
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7. Monitoring Cerebral Perfusion Changes Using Arterial Spin-Labeling Perfusion MRI after Indirect Revascularization in Children with Moyamoya Disease
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Yeon Jin Cho, Jung Eun Cheon, Young Hun Choi, Seunghyun Lee, Woo Sun Kim, and Seul Bi Lee
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Male ,030218 nuclear medicine & medical imaging ,Moyamoya disease ,03 medical and health sciences ,0302 clinical medicine ,Indirect revascularization ,medicine.artery ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Cerebral perfusion pressure ,Child ,Children ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Pediatric Imaging ,medicine.disease ,Magnetic Resonance Imaging ,Perfusion ,Arterial spin-labeling ,Cerebral blood flow ,Cerebrovascular Circulation ,Child, Preschool ,030220 oncology & carcinogenesis ,Arterial spin labeling ,Middle cerebral artery ,Original Article ,Female ,Spin Labels ,business ,Nuclear medicine ,Magnetic Resonance Angiography - Abstract
OBJECTIVE: To assess the role of arterial spin-labeling (ASL) perfusion MRI in identifying cerebral perfusion changes after indirect revascularization in children with moyamoya disease. MATERIALS AND METHODS: We included pre- and postoperative perfusion MRI data of 30 children with moyamoya disease (13 boys and 17 girls; mean age ± standard deviation, 6.3 ± 3.0 years) who underwent indirect revascularization between June 2016 and August 2017. Relative cerebral blood flow (rCBF) and qualitative perfusion scores for arterial transit time (ATT) effects were evaluated in the middle cerebral artery (MCA) territory on ASL perfusion MRI. The rCBF and relative time-to-peak (rTTP) values were also measured using dynamic susceptibility contrast (DSC) perfusion MRI. Each perfusion change on ASL and DSC perfusion MRI was analyzed using the paired t test. We analyzed the correlation between perfusion changes on ASL and DSC images using Spearman's correlation coefficient. RESULTS: The ASL rCBF values improved at both the ganglionic and supraganglionic levels of the MCA territory after surgery (p = 0.040 and p = 0.003, respectively). The ATT perfusion scores also improved at both levels (p < 0.001 and p < 0.001, respectively). The rCBF and rTTP values on DSC MRI showed significant improvement at both levels of the MCA territory of the operated side (all p < 0.05). There was no significant correlation between the improvements in rCBF values on the two perfusion images (r = 0.195, p = 0.303); however, there was a correlation between the change in perfusion scores on ASL and rTTP on DSC MRI (r = 0.701, p < 0.001). CONCLUSION: Recognizing the effects of ATT on ASL perfusion MRI may help monitor cerebral perfusion changes and complement quantitative rCBF assessment using ASL perfusion MRI in patients with moyamoya disease after indirect revascularization.
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- 2021
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8. Monitoring Cerebral Perfusion Changes Using Arterial Spin-Labeling Perfusion MRI after Indirect Revascularization in Children with Moyamoya Disease.
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Seul Bi Lee, Seunghyun Lee, Yeon Jin Cho, Young Hun Choi, Jung-Eun Cheon, and Woo Sun Kim
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- 2021
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9. Incidence and Risk Factors of Nausea and Vomiting after Exposure to Low-Osmolality Iodinated Contrast Media in Children: A Focus on Preparative Fasting
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Jung Eun Cheon, Seunghyun Lee, Ji Young Ha, Woo Sun Kim, Seul Bi Lee, Yeon Jin Cho, Young Hun Choi, and Gayoung Choi
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Male ,medicine.medical_specialty ,Adolescent ,Vomiting ,Nausea ,medicine.medical_treatment ,Iomeprol ,Aspiration pneumonia ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Odds Ratio ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Computed tomography ,Children ,Chemotherapy ,business.industry ,Contrast media ,Incidence ,Incidence (epidemiology) ,Osmolar Concentration ,Infant, Newborn ,Infant ,Pediatric Imaging ,Fasting ,Odds ratio ,medicine.disease ,Logistic Models ,chemistry ,Child, Preschool ,030220 oncology & carcinogenesis ,Original Article ,Female ,medicine.symptom ,Iohexol ,Tomography, X-Ray Computed ,business ,medicine.drug - Abstract
Objective To evaluate the incidence and risk factors of emetic complications associated with the intravenous administration of low-osmolality iodinated contrast media (ICM) in children undergoing computed tomography (CT). Materials and methods All children who underwent contrast-enhanced CT between April 2017 and July 2019 were included. Pediatric patients were instructed on the preparative dietary protocol at our institution. Experienced nurses in the radiology department monitored the children during the CT scans and recorded any emetic complications in their electronic medical records. These data were used to calculate the incidence of emetic complications. Various patient factors and technical factors, including fasting duration, the type and volume of ICM, and ongoing chemotherapy, were evaluated to identify risk factors for emetic complications using univariate and multivariate logistic regression analyses. Results Among the 864 children (mean age, 8.4 ± 5.7 years) evaluated, 18 (2.1%) experienced emetic complications (6 experienced nausea only and 12 experienced nausea and vomiting). None of the children developed aspiration pneumonia. The mean fasting duration of patients with emesis was 7.9 ± 5.7 hours (range, 3-21 hours), whereas that of patients without nausea was 8.7 ± 5.7 hours (range, 0-24 hours). Fasting duration was not associated with the development of nausea and vomiting (p = 0.634). Multivariate logistic regression analysis revealed that ongoing chemotherapy (odds ratio [OR] = 4.323; 95% confidence interval [CI] = 1.430-13.064; p = 0.009), iomeprol use (OR = 7.219; 95% CI = 1.442-36.146; p = 0.016), and iohexol use (OR = 5.241; 95% CI = 1.350-20.346; p = 0.017) were independent risk factors for emetic complications. Conclusion Only a small proportion (2.1%) of children experienced nausea or vomiting after exposure to low-osmolality ICM. Many children underwent excessive fasting; however, fasting duration was not associated with nausea and vomiting. Moreover, ongoing chemotherapy and the use of iomeprol or iohexol were identified as potential risk factors for emetic complications in children.
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- 2020
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10. Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs.
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Hyoung Suk Park, Kiwan Jeon, Yeon Jin Cho, Se Woo Kim, Seul Bi Lee, Gayoung Choi, Seunghyun Lee, Young Hun Choi, Jung-Eun Cheon, Woo Sun Kim, Young Jin Ryu, and Jae-Yeon Hwang
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- 2021
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11. Development of a New Korean Standard Bone Age Model: A Paradigm for AI-Powered Pediatric Imaging.
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Jung-Eun Cheon
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- 2023
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12. Optimal Kiloelectron Volt for Noise-Optimized Virtual Monoenergetic Images of Dual-Energy Pediatric Abdominopelvic Computed Tomography: Preliminary Results
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Su Mi Shin, Ji Eun Park, Bernhard Krauss, Seong Yong Pak, Taek Min Kim, Woo Sun Kim, In One Kim, Young Hun Choi, and Jung Eun Cheon
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Male ,Adolescent ,Image quality ,Virtual monoenergetic image ,Noise-optimized VMI ,Computed tomography ,Signal-To-Noise Ratio ,Noise (electronics) ,030218 nuclear medicine & medical imaging ,Radiography, Dual-Energy Scanned Projection ,03 medical and health sciences ,0302 clinical medicine ,Dual-energy pediatric abdominopelvic CT ,Image noise ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Child ,Pancreas ,Aorta ,Retrospective Studies ,Dual energy ,medicine.diagnostic_test ,business.industry ,Infant ,Volt ,Pediatric Imaging ,Liver ,Conventional VMI ,Child, Preschool ,030220 oncology & carcinogenesis ,Radiographic Image Interpretation, Computer-Assisted ,Original Article ,Female ,Tomography, X-Ray Computed ,business ,Nuclear medicine ,Algorithms - Abstract
Objective To compare quantitative and qualitative image quality parameters in pediatric abdominopelvic dual-energy CT (DECT) using noise-optimized virtual monoenergetic image (VMI) and conventional VMI at different kiloelectron volt (keV) levels. Materials and Methods Thirty-six consecutive abdominopelvic DECT scans were retrospectively included. Noise-optimized VMI and conventional VMI were reconstructed at seven energy levels, from 40 keV to 100 keV at 10 keV intervals. The contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) of the liver, pancreas, and aorta were objectively measured and compared. Image quality was evaluated subjectively regarding image noise, image blurring of solid organ, bowel image quality and severity of beam-hardening artifacts. Optimal monoenergetic levels in keV for both algorithms were determined based on overall image quality score. Results The maximal CNR and SNR values for all investigated organs were observed at 40 keV in noise-optimized VMI (CNR and SNR of liver, pancreas, aorta in order [CNR; 20.93, 17.34, 46.75: SNR; 37.39, 33.80, 63.21]), at 60–70 keV and at 70 keV in conventional VMI (CNR; 8.12, 5.67, 15.97: SNR; 19.57, 16.66, 26.65). In qualitative image analysis, noise-optimized VMI and conventional VMI showed the best overall image quality scores at 60 keV and at 70 keV, respectively. Noise-optimized VMI at 60 keV showed superior CNRs, SNRs, and overall image quality scores compared to conventional VMI at 70 keV (p < 0.001). Conclusion Optimal energy levels for noise-optimized VMI and conventional VMI were 60 keV and at 70 keV, respectively. Noise-optimized VMI shows superior CNRs, SNRs and subjective image quality over conventional VMI, at the optimal energy level.
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- 2019
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13. Arterial Spin Labeling MRI for Quantitative Assessment of Cerebral Perfusion Before and After Cerebral Revascularization in Children with Moyamoya Disease
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Ji Young Ha, Woo Sun Kim, Young Hun Choi, In One Kim, Seunghyun Lee, Yeon Jin Cho, and Jung Eun Cheon
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Male ,Middle Cerebral Artery ,Adolescent ,Arterial spin labeling ,medicine.medical_treatment ,Cerebral Revascularization ,Revascularization ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Cerebral perfusion ,medicine.artery ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Moyamoya disease ,Cerebral perfusion pressure ,Child ,Retrospective Studies ,Pediatric ,medicine.diagnostic_test ,business.industry ,Angiography ,Angiography, Digital Subtraction ,Pediatric Imaging ,Digital subtraction angiography ,Cerebral blood flow ,medicine.disease ,Magnetic Resonance Imaging ,Perfusion ,Cerebrovascular Circulation ,Child, Preschool ,030220 oncology & carcinogenesis ,Middle cerebral artery ,Original Article ,Female ,Spin Labels ,Moyamoya Disease ,Nuclear medicine ,business ,Moyamoya ,Algorithms - Abstract
Objective To determine the correlation between cerebral blood flow (CBF) on arterial spin labeling (ASL) MRI and the degree of postoperative revascularization assessed on digital subtraction angiography in children with moyamoya disease (MMD). Materials and methods Twenty-one children (9 boys and 12 girls; mean age, 8.4 ± 3.6 years; age range, 3-16 years) with MMD who underwent both pseudocontinuous ASL MRI at 1.5T and catheter angiography before and after superficial temporal artery encephaloduroarteriosynangiosis were included in this retrospective study. The degree of revascularization in the middle cerebral artery (MCA) territory was evaluated on external carotid angiography and was graded on a 3-point scale. On ASL CBF maps, regions of interest were manually drawn over the MCA territory of the operated side at the level of the centrum semi-ovale and over the cerebellum. The normalized CBF (nCBF) was calculated by dividing the CBF of the MCA territory by the CBF of the cerebellum. Changes in nCBFs were calculated by subtracting the preoperative nCBF values from the postoperative nCBF values. The correlation between nCBF changes measured with ASL and the revascularization grade from direct angiography was evaluated. Results The nCBF value on the operated side increased after the operation (p = 0.001). The higher the degree of revascularization, the greater the nCBF change was: poor revascularization (grade 1), -0.043 ± 0.212; fair revascularization (grade 2), 0.345 ± 0.176; good revascularization (grade 3), 0.453 ± 0.182 (p = 0.005, Jockheere-Terpstra test). The interobserver agreement was excellent for the measured CBF values of the three readers (0.91-0.97). Conclusion The nCBF values of the MCA territory obtained from ASL MRI increased after the revascularization procedure in children with MMD, and the degree of nCBF change showed a significant correlation with the degree of collateral formation evaluated via catheter angiography.
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- 2019
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14. Application of Vendor-Neutral Iterative Reconstruction Technique to Pediatric Abdominal Computed Tomography
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Ji Eun Park, Yeon Jin Cho, Young Hun Choi, Woo Hyeon Lim, Seunghyun Lee, Jung Eun Cheon, Jong Hyo Kim, Woo Sun Kim, and In One Kim
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Male ,Adolescent ,Phantom ,Image quality ,Iterative reconstruction ,Signal-To-Noise Ratio ,Radiation Dosage ,Imaging phantom ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Hounsfield scale ,Abdomen ,Humans ,Medicine ,Idose ,Radiology, Nuclear Medicine and imaging ,Child ,Computed tomography ,Image resolution ,Pediatric ,Radon transform ,Phantoms, Imaging ,business.industry ,Infant ,Pediatric Imaging ,Vendor-neutral ,Noise ,chemistry ,Child, Preschool ,030220 oncology & carcinogenesis ,Radiographic Image Interpretation, Computer-Assisted ,Female ,Original Article ,Tomography, X-Ray Computed ,business ,Nuclear medicine - Abstract
Objective To compare image qualities between vendor-neutral and vendor-specific hybrid iterative reconstruction (IR) techniques for abdominopelvic computed tomography (CT) in young patients. Materials and Methods In phantom study, we used an anthropomorphic pediatric phantom, age-equivalent to 5-year-old, and reconstructed CT data using traditional filtered back projection (FBP), vendor-specific and vendor-neutral IR techniques (ClariCT; ClariPI) in various radiation doses. Noise, low-contrast detectability and subjective spatial resolution were compared between FBP, vendor-specific (i.e., iDose1 to 5; Philips Healthcare), and vendor-neutral (i.e., ClariCT1 to 5) IR techniques in phantom. In 43 patients (median, 14 years; age range 1–19 years), noise, contrast-to-noise ratio (CNR), and qualitative image quality scores of abdominopelvic CT were compared between FBP, iDose level 4 (iDose4), and ClariCT level 2 (ClariCT2), which showed most similar image quality to clinically used vendor-specific IR images (i.e., iDose4) in phantom study. Noise, CNR, and qualitative imaging scores were compared using one-way repeated measure analysis of variance. Results In phantom study, ClariCT2 showed noise level similar to iDose4 (14.68–7.66 Hounsfield unit [HU] vs. 14.78–6.99 HU at CT dose index volume range of 0.8–3.8 mGy). Subjective low-contrast detectability and spatial resolution were similar between ClariCT2 and iDose4. In clinical study, ClariCT2 was equivalent to iDose4 for noise (14.26–17.33 vs. 16.01–18.90) and CNR (3.55–5.24 vs. 3.20–4.60) (p > 0.05). For qualitative imaging scores, the overall image quality ([reader 1, reader 2]; 2.74 vs. 2.07, 3.02 vs. 2.28) and noise (2.88 vs. 2.23, 2.93 vs. 2.33) of ClariCT2 were superior to those of FBP (p < 0.05), and not different from those of iDose4 (2.74 vs. 2.72, 3.02 vs. 2.98; 2.88 vs. 2.77, 2.93 vs. 2.86) (p > 0.05). Conclusion Vendor-neutral IR technique shows image quality similar to that of clinically used vendor-specific hybrid IR technique for abdominopelvic CT in young patients.
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- 2019
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15. Incidence and Risk Factors of Nausea and Vomiting after Exposure to Low-Osmolality Iodinated Contrast Media in Children: A Focus on Preparative Fasting.
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Ji Young Ha, Young Hun Choi, Yeon Jin Cho, Seunghyun Lee, Seul Bi Lee, Gayoung Choi, Jung-Eun Cheon, and Woo Sun Kim
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- 2020
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16. Bronchopulmonary dysplasia: new high resolution computed tomography scoring system and correlation between the high resolution computed tomography score and clinical severity
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Han Suk Kim, Jung Eun Cheon, Whal Lee, Ah Young Jung, Su Mi Shin, Jung Hwan Choi, Woo Sun Kim, and In One Kim
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Male ,High-resolution computed tomography ,medicine.medical_specialty ,Scoring system ,Radiography ,Chest radiography ,Gestational Age ,Severity of Illness Index ,Correlation ,mental disorders ,medicine ,Humans ,Infant, Very Low Birth Weight ,Radiology, Nuclear Medicine and imaging ,Clinical severity ,Prospective Studies ,Molecular epidemiology Aetiology, screening and detection [NCEBP 1] ,medicine.diagnostic_test ,business.industry ,Infant, Newborn ,Preterm infants ,Reproducibility of Results ,Pediatric Imaging ,respiratory system ,medicine.disease ,Bronchopulmonary dysplasia ,respiratory tract diseases ,HRCT ,Original Article ,Female ,Radiology ,business ,Tomography, X-Ray Computed ,Infant, Premature - Abstract
Contains fulltext : 118083.pdf (Publisher’s version ) (Open Access) OBJECTIVE: To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score. MATERIALS AND METHODS: Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity. RESULTS: The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001). CONCLUSION: We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.
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- 2013
17. Ultrasonographic Diagnosis of Biliary Atresia Based on a Decision-Making Tree Model
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So Mi, Lee, Jung-Eun, Cheon, Young Hun, Choi, Woo Sun, Kim, Hyun-Hae, Cho, Hyun-Hye, Cho, In-One, Kim, and Sun Kyoung, You
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Male ,medicine.medical_specialty ,Cord ,Decision trees ,Decision Making ,Logistic regression ,Gastroenterology ,Sensitivity and Specificity ,Diagnosis, Differential ,Hepatic Artery ,Biliary atresia ,Biliary Atresia ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Retrospective Studies ,Ultrasonography ,Common Bile Duct ,US ,Common bile duct ,business.industry ,Portal Vein ,Gallbladder ,Abnormal gallbladder morphology ,Ultrasound ,Infant, Newborn ,Infant ,Pediatric Imaging ,medicine.disease ,Jaundice, Obstructive ,medicine.anatomical_structure ,Logistic Models ,ROC Curve ,Area Under Curve ,Original Article ,Female ,Neonatal jaundice ,Differential diagnosis ,Erratum ,Nuclear medicine ,business - Abstract
Objective To assess the diagnostic value of various ultrasound (US) findings and to make a decision-tree model for US diagnosis of biliary atresia (BA). Materials and Methods From March 2008 to January 2014, the following US findings were retrospectively evaluated in 100 infants with cholestatic jaundice (BA, n = 46; non-BA, n = 54): length and morphology of the gallbladder, triangular cord thickness, hepatic artery and portal vein diameters, and visualization of the common bile duct. Logistic regression analyses were performed to determine the features that would be useful in predicting BA. Conditional inference tree analysis was used to generate a decision-making tree for classifying patients into the BA or non-BA groups. Results Multivariate logistic regression analysis showed that abnormal gallbladder morphology and greater triangular cord thickness were significant predictors of BA (p = 0.003 and 0.001; adjusted odds ratio: 345.6 and 65.6, respectively). In the decision-making tree using conditional inference tree analysis, gallbladder morphology and triangular cord thickness (optimal cutoff value of triangular cord thickness, 3.4 mm) were also selected as significant discriminators for differential diagnosis of BA, and gallbladder morphology was the first discriminator. The diagnostic performance of the decision-making tree was excellent, with sensitivity of 100% (46/46), specificity of 94.4% (51/54), and overall accuracy of 97% (97/100). Conclusion Abnormal gallbladder morphology and greater triangular cord thickness (> 3.4 mm) were the most useful predictors of BA on US. We suggest that the gallbladder morphology should be evaluated first and that triangular cord thickness should be evaluated subsequently in cases with normal gallbladder morphology.
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- 2015
18. Application of Vendor-Neutral Iterative Reconstruction Technique to Pediatric Abdominal Computed Tomography.
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Woo Hyeon Lim, Young Hun Choi, Ji Eun Park, Yeon Jin Cho, Seunghyun Lee, Jung-Eun Cheon, Woo Sun Kim, In-One Kim, and Jong Hyo Kim
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- 2019
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19. Optimal Kiloelectron Volt for Noise-Optimized Virtual Monoenergetic Images of Dual-Energy Pediatric Abdominopelvic Computed Tomography: Preliminary Results.
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Taek Min Kim, Young Hun Choi, Jung-Eun Cheon, Woo Sun Kim, In-One Kim, Ji Eun Park, Su-mi Shin, Seong Yong Pak, and Krauss, Bernhard
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- 2019
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20. Erratum: Ultrasonographic Diagnosis of Biliary Atresia Based on a Decision-Making Tree Model
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So Mi Lee, Jung-Eun Cheon, Young Hun Choi, Woo Sun Kim, Hyun-Hae Cho, In-One Kim, and Sun Kyoung You
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Radiology, Nuclear Medicine and imaging - Published
- 2016
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21. Unusual thymic hyperplasia mimicking lipomatous tumor in an eight-year-old boy with concomitant pericardial lipomatosis and right facial hemihypertrophy
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Yoo Jin Kim, Sun Ju Byun, Jung Eun Cheon, Kyeong Cheon Jung, In One Kim, Woo Sun Kim, Kyung Mo Yeon, and Yun Jung Lim
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Male ,medicine.medical_specialty ,Pathology ,Heart Diseases ,Lipomatosis ,Case Report ,Diagnosis, Differential ,Anterior mediastinal mass ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Magnetic resonance imaging (MRI) ,Facial hemihypertrophy ,Child ,Hemihypertrophy ,Children ,Computed tomography (CT) ,Lipomatous tumor ,Pediatric ,Thymic hyperplasia ,business.industry ,Pericardial lipomatosis ,Mediastinum ,Mediastinal mass ,Hypertrophy ,Hyperplasia ,medicine.disease ,Magnetic Resonance Imaging ,Thymus ,medicine.anatomical_structure ,Facial Asymmetry ,Concomitant ,Radiology ,Thymus Hyperplasia ,business ,Tomography, X-Ray Computed ,Pericardium - Abstract
We report a case of thymic hyperplasia accompanied by pericardial lipomatosis and right facial hemihypertrophy in an 8-year-old boy. On imaging studies, the hyperplastic thymus had prominent curvilinear and nodular fatty areas simulating a fat-containing anterior mediastinal mass, which is an unusual finding in children. To our knowledge, this is the first report on a child with a combination of thymic hyperplasia, pericardial lipomatosis, and right facial hemihypertrophy. The radiologic findings are presented with a brief discussion.
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- 2010
22. Clinical application of liver MR imaging in Wilson's disease
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Woo Sun Kim, In One Kim, Cheong Il Shin, Jeong Min Lee, Jae Sung Ko, Jeong Kee Seo, Kyung Mo Yeon, and Jung Eun Cheon
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Adult ,Male ,Pathology ,medicine.medical_specialty ,Cirrhosis ,Adolescent ,Disease ,Statistics, Nonparametric ,Image Interpretation, Computer-Assisted ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Retrospective Studies ,Kidney ,Chi-Square Distribution ,medicine.diagnostic_test ,business.industry ,Retrospective cohort study ,Magnetic resonance imaging ,Magnetic resonance (MR) ,medicine.disease ,Hepatolenticular degeneration ,Magnetic Resonance Imaging ,Wilson's disease ,Exact test ,medicine.anatomical_structure ,Liver ,Child, Preschool ,Female ,Original Article ,business ,Chi-squared distribution - Abstract
Objective: To determine whether there is a correlation between liver MR find-ings and the clinical manifestations and severity of liver dysfunction in patientswith Wilson’s disease.Materials and Methods: Two radiologists retrospectively evaluated MRimages of the liver in 50 patients with Wilson’s disease. The Institutional ReviewBoard approved this retrospective study and informed consent was waived. MRimages were evaluated with a focus on hepatic contour abnormalities and thepresence of intrahepatic nodules. By using Fisher’s exact test, MR findings werecompared with clinical presentations (neurological and non-neurological) andhepatic dysfunction, which was categorized by the Child-Pugh classification sys-tem (A, B and C). Follow-up MR images were available for 17 patients.Results: Contour abnormalities of the liver and intrahepatic nodules wereobserved in 31 patients (62%) and 25 patients (50%), respectively. Each MR find-ing showed a statistically significant difference ( p < 0.05) among the three groupsof Child-Pugh classifications (A, n = 36; B, n = 5; C, n = 9), except forsplenomegaly ( p = 0.243). The mean age of the patients with positive MR find-ings was higher than that of patients with negative MR findings. For patients withChild-Pugh class A (n = 36) with neurological presentation, intrahepatic nodules,surface nodularity, and gallbladder fossa widening were more common.Intrahepatic nodules were improved (n = 8, 47%), stationary (n = 5, 29%), oraggravated (n = 4, 24%) on follow-up MR images.Conclusion: MR imaging demonstrates the contour abnormalities andparenchymal nodules of the liver in more than half of the patients with Wilson’sdisease, which correlates with the severity of hepatic dysfunction and clinicalmanifestations. ilson’s disease or progressive hepatolenticular degeneration is an autoso-mal recessive disorder of copper metabolism (1). The gene that causesWilson’s disease, located at chromosome 13 band q14.3, is known tocode for a copper-transporting P-type ATPase (2-4). A mutation of the gene associ-ated with Wilson’s disease results in deficient biliary excretion of copper, leading toexcessive copper accumulation in many tissues. Copper accumulation occurs mainly inthe liver, but also in the brain, cornea, and kidney (1-5). The principal clinical manifes-tations of Wilson’s disease are either hepatic or neurological disease (6, 7). Ultrasound (US), CT, and MR findings of the liver in Wilson’s disease usually reflectnonspecific hepatic injury including fatty infiltration, acute hepatitis, chronic activehepatitis, and cirrhosis (8-12). In advanced Wilson’s disease, nodular infiltrationssuggesting the presence of copper-containing nodules and contour abnormalities consis-Jung-Eun Cheon, MD
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- 2010
23. Effect of Arterial Deprivation on Growing Femoral Epiphysis: Quantitative Magnetic Resonance Imaging Using a Piglet Model
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Jung Eun Cheon, In-One Kim, Won Joon Yoo, Young Hun Choi, and Woo Sun Kim
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Male ,medicine.medical_specialty ,Swine ,medicine.medical_treatment ,Embolism ,Ischemia ,Dynamic contrast enhanced MRI ,Femoral head ,Medial circumflex femoral artery ,medicine.artery ,Animals ,Medicine ,Radiology, Nuclear Medicine and imaging ,Embolization ,Pelvic Bones ,medicine.diagnostic_test ,business.industry ,Osteonecrosis ,Femoral head ischemia ,Femur Head ,Magnetic resonance imaging ,Arteries ,Pediatric Imaging ,medicine.disease ,Disease Models, Animal ,Diffusion Magnetic Resonance Imaging ,medicine.anatomical_structure ,Reperfusion Injury ,Dynamic contrast-enhanced MRI ,Original Article ,Diffusion-weighted imaging ,Radiology ,business ,Epiphyses ,Perfusion - Abstract
Objective: To investigate the usefulness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion MRI for the evaluation of femoral head ischemia. Materials and Methods: Unilateral femoral head ischemia was induced by selective embolization of the medial circumflex femoral artery in 10 piglets. All MRIs were performed immediately (1 hour) and after embolization (1, 2, and 4 weeks). Apparent diffusion coefficients (ADCs) were calculated for the femoral head. The estimated pharmacokinetic parameters (Kep and Ve from two-compartment model) and semi-quantitative parameters including peak enhancement, time-to-peak (TTP), and contrast washout were evaluated. Results: The epiphyseal ADC values of the ischemic hip decreased immediately (1 hour) after embolization. However, they increased rapidly at 1 week after embolization and remained elevated until 4 weeks after embolization. Perfusion MRI of ischemic hips showed decreased epiphyseal perfusion with decreased Kep immediately after embolization. Signal intensitytime curves showed delayed TTP with limited contrast washout immediately post-embolization. At 1−2 weeks after embolization, spontaneous reperfusion was observed in ischemic epiphyses. The change of ADC (p = 0.043) and Kep (p = 0.043) were significantly different between immediate (1 hour) after embolization and 1 week post-embolization. Conclusion: Diffusion MRI and pharmacokinetic model obtained from the DCE-MRI are useful in depicting early changes of perfusion and tissue damage using the model of femoral head ischemia in skeletally immature piglets. Index terms: Diffusion-weighted imaging; Dynamic contrast enhanced MRI; Femoral head ischemia
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- 2015
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24. Balloon Dilatation for Corrosive Esophageal Strictures in Children: Radiologic and Clinical Outcomes
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Su Mi Shin, In One Kim, Jung Eun Cheon, Woo Sun Kim, Wha Young Kim, Kyung Mo Yeon, and Byung Jae Youn
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Male ,medicine.medical_specialty ,Corrosive esophagitis ,Caustics ,Balloon dilatation ,Lye ,Anastomosis ,Gastroenterology ,Catheterization ,Esophagus ,Internal medicine ,Burns, Chemical ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Children ,Esophageal stricture ,Acetic Acid ,Retrospective Studies ,business.industry ,Balloon catheter ,Infant ,Dysphagia ,medicine.disease ,Corrosive substance ,Surgery ,Radiography ,Treatment Outcome ,medicine.anatomical_structure ,Coagulative necrosis ,Child, Preschool ,Atresia ,Esophageal Stenosis ,Original Article ,Female ,medicine.symptom ,Deglutition Disorders ,business - Abstract
Objective: We retrospectively evaluated the effectiveness of the esophagealballoon dilatation (EBD) in children with a corrosive esophageal stricture.Materials and Methods: The study subjects included 14 patients (M:F = 8:6,age range: 17 -85 months) who underwent an EBD due to a corrosiveesophageal stricture. The causative agents for the condition were glacial aceticacid (n = 9) and lye (n = 5).Results: A total of 52 EBD sessions were performed in 14 patients (range 1-8sessions). During the mean 15-month follow-up period (range 1 -79 months), 12patients (86%) underwent additional EBD due to recurrent esophageal stricture.Dysphagia improved after each EBD session and oral feeding was possiblebetween EBD sessions. Long-term success (defined as dysphagia relief for atleast 12 months after the last EBD) was achieved in two patients (14%).Temporary success of EBD (defined as dysphagia relief for at least one monthafter the EBD session) was achieved in 17 out of 52 sessions (33%). A submu-cosal tear of the esophagus was observed in two (4%) sessions of EBD.Conclusion: Only a limited number of children with corrosive esophageal stric-tures were considered cured by EBD. However, the outcome of repeated EBDwas sufficient to allow the children to eat per os prior to surgical management.he accidental ingestion of a corrosive substance is a common cause ofesophageal strictures in children (1). Corrosive substances, whether acidor alkali, can both cause significant esophageal strictures, thoughreactions differ (i.e., acids cause coagulation necrosis of the mucosa, whereas alkalis,like lye, produce liquefaction necrosis that may penetrate deeper layers includingmuscular layers) (2). Because glacial acetic acid is still used domestically by some as afood seasoning in East Asia, the occurrence of accidental acid ingestion and ofsubsequent corrosive esophageal stricture development is more frequent in East Asiathan in other parts of the world (3, 4).Treatment for esophageal strictures in children has evolved from surgical revision, toesophageal bougienage, and to the currently used esophageal balloon dilatation (EBD)(5). Since London et al. (6) reported the successful treatment of esophageal strictureswith a Gruentzig-type balloon catheter in 1981, EBD has been accepted as a safe andeffective treatment for benign esophageal strictures (2, 7-9). In infants and children,this technique has been primarily used to treat anastomotic strictures resulting fromsurgery for esophageal atresia (7-10). However, although EBD is considered as a safeand effective treatment for esophageal stricture, to the best of our knowledge, itssafety and effectiveness for the treatment of corrosive esophageal stricture in childrenhas rarely been reported (11-14). The purpose of our study was to retrospectivelyByung Jae Youn, MDWoo Sun Kim, MDJung-Eun Cheon, MDWha-Young Kim, MDSu-Mi Shin, MDIn-One Kim, MDKyung Mo Yeon, MD
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- 2010
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25. Imperforate Anus: Determination of Type Using Transperineal Ultrasonography
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In-One Kim, Woo Sun Kim, Young Hun Choi, Jung Eun Cheon, and Kyung Mo Yeon
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Male ,medicine.medical_specialty ,Fistula ,Anus ,Diagnostic accuracy ,Corrective surgery ,Ultrasound (US) ,Anus, Imperforate ,Transperineal ultrasonography ,medicine ,Humans ,Rectal Fistula ,Radiology, Nuclear Medicine and imaging ,Ultrasonography ,Rectal pouch ,business.industry ,Infant, Newborn ,Urinary Bladder Diseases ,Infant ,medicine.disease ,Surgery ,Perineum ,medicine.anatomical_structure ,Female ,Original Article ,Radiology ,business ,Imperforate anus - Abstract
Objective This study was designed to assess the usefulness of transperineal ultrasonography (US) for the determination of imperforate anus (IA) type. Materials and Methods From January 2000 to December 2004, 46 of 193 patients with an IA underwent transperineal US prior to corrective surgery. Sonographic findings were reviewed to identify the presence of internal fistulas and to determine "distal rectal pouch to perineum (P-P)" distances. IA types were determined based on the sonographic findings, and the diagnostic accuracy of transperineal US was evaluated based on surgical findings. Results Of the 46 patients, 17 patients were surgically confirmed as having a high-type IA, three patients were confirmed as having an intermediate-type IA and 26 patients were confirmed as having a low-type IA. The IA type was correctly diagnosed by the use of transperineal US in 39 of the 46 patients (85%). In 14 of the 17 patients with a high-type IA, internal fistulas were correctly identified. All cases with a P-P distance > 16 mm were high-type IAs and all cases with a P-P distance < 5 mm were low-type IAs. Conclusion Transperineal US is a good diagnostic modality for the identification of internal fistulas in cases of high-type IA and for defining the IA level.
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- 2009
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26. The Korean Journal of Radiology Launches an Online Manuscript Submission and Tracking System for Peer Review
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Kyung Soo Lee and Jung Eun Cheon
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medicine.medical_specialty ,Editorial ,business.industry ,Medicine ,Radiology, Nuclear Medicine and imaging ,Tracking system ,Medical physics ,business - Published
- 2005
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27. CT and Pathologic Findings of A Case of Subdural Osteoma
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Jieun Kim, Hee Jin Yang, and Jung Eun Cheon
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Adult ,medicine.medical_specialty ,Skull Neoplasms ,Case Report ,Meninges, CT ,Subdural Space ,Meninges, neoplasm ,X ray computed ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Neurological findings ,Osteoma ,business.industry ,Persistent headache ,Nodule (medicine) ,medicine.disease ,Skull ,medicine.anatomical_structure ,Plain radiography ,Homogeneous ,Frontal Bone ,Female ,Radiology ,medicine.symptom ,Tomography, X-Ray Computed ,business - Abstract
A 43-year-old female presented with persistent headache and dizziness which had first occurred two years earlier. The physical and neurological findings at admission were unremarkable, though plain radiography revealed the presence of a dense calcified mass in the left frontal area, and CT showed that a homogeneous high-density nodule was attached to the inner surface of the left frontal skull. The hard bony mass found and excised during surgery was shown at histopathologic examination to be a subdural osteoma. We describe the clinicopathologic findings of this entity and discuss the radiological features which suggest its subdural location.
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- 2002
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