1. Obesity and Hypertension in Association with Diastolic Dysfunction Could Reduce Exercise Capacity
- Author
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Myeong Gun Kim, Bong Roung Kim, Mi-Seung Shin, JinShil Kim, Yae Min Park, Min Young Baek, and Se-Won Kang
- Subjects
Cardiac function curve ,medicine.medical_specialty ,Diastolic function ,Diastole ,030204 cardiovascular system & hematology ,Cardiac dysfunction ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Internal Medicine ,medicine ,Exercise capacity ,030212 general & internal medicine ,Obesity ,Disease burden ,business.industry ,medicine.disease ,Echocardiography ,Hypertension ,Cardiology ,Original Article ,Erratum ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background and Objectives Empirical evidence is lacking on the cumulative disease burden of obesity and hypertension and its impact on cardiac function and exercise capacity. The purpose of this study was to determine whether the presence of obesity and hypertension together was associated with cardiac dysfunction and exercise capacity. Subjects and Methods Using a retrospective study design, medical records were reviewed for echocardiographic and treadmill exercise stress test data. Subjects were grouped according to four categories: normal control, obese, hypertensive, or obese and hypertensive. Results Obese, hypertensive persons showed significantly lower Ea and E/A ratio and greater E/Ea ratio, deceleration time, left ventricular (LV) mass, and LV mass index compared to their counter parts (normal control, obese and/or hypertensive) (all p
- Published
- 2016