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In an experiment on 66 mongrel dogs of both sexes weighing from 6 to 24 kg, under thiopental sodium narcosis (40 mg/kg), the effectiveness of infusion therapy of a IIIB--IV degree burn of 5% of the body surface complicated by blood loss (30-35 ml/kg) was studied. Without treatment, the animals died within 1 h. Reinfusion didn't lead to restoration of hemodynamic indices. Irrespective of the method of blood injection (intraarterial, intravenous, intraosteal), the animals died within 24 h. Blood reinfusion, introduction of polyglucin in 1:1 proportion increased the duration of life of the animals 2.5-fold when compared with introduction of the blood alone.