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Your search keyword '"Coca, Steven G."' showing total 26 results
Start Over Author "Coca, Steven G." Journal kidney international
26 results on '"Coca, Steven G."'

1. The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events

Author

Menez, Steven, Wen, Yumeng, Xu, Leyuan, Moledina, Dennis G., Thiessen-Philbrook, Heather, Hu, David, Obeid, Wassim, Bhatraju, Pavan K., Ikizler, T. Alp, Siew, Edward D., Chinchilli, Vernon M., Garg, Amit X., Go, Alan S., Liu, Kathleen D., Kaufman, James S., Kimmel, Paul L., Himmelfarb, Jonathan, Coca, Steven G., Cantley, Lloyd G., and Parikh, Chirag R.

Published
2023
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2. A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death.

Author

Ikizler, T Alp, Parikh, Chirag R, Himmelfarb, Jonathan, Chinchilli, Vernon M, Liu, Kathleen D, Coca, Steven G, Garg, Amit X, Hsu, Chi-Yuan, Siew, Edward D, Wurfel, Mark M, Ware, Lorraine B, Faulkner, Georgia Brown, Tan, Thida C, Kaufman, James S, Kimmel, Paul L, Go, Alan S, and ASSESS-AKI Study Investigators

Subjects
ASSESS-AKI Study Investigators, Kidney, Humans, Cardiovascular Diseases, Glomerular Filtration Rate, Aftercare, Patient Discharge, Risk Factors, Prospective Studies, Adult, Acute Kidney Injury, acute kidney injury, acute renal failure, cardiovascular disease, chronic kidney disease, heart failure, mortality, Cardiovascular, Clinical Research, Kidney Disease, Aging, Renal and urogenital, Urology & Nephrology, Clinical Sciences
Abstract

Acute kidney injury (AKI) has been reported to be associated with excess risks of death, kidney disease progression and cardiovascular events although previous studies have important limitations. To further examine this, we prospectively studied adults from four clinical centers surviving three months and more after hospitalization with or without AKI who were matched on center, pre-admission CKD status, and an integrated priority score based on age, prior cardiovascular disease or diabetes mellitus, preadmission estimated glomerular filtration rate (eGFR) and treatment in the intensive care unit during the index hospitalization between December 2009-February 2015, with follow-up through November 2018. All participants had assessments of kidney function before (eGFR) and at three months and annually (eGFR and proteinuria) after the index hospitalization. Associations of AKI with outcomes were examined after accounting for pre-admission and three-month post-discharge factors. Among 769 AKI (73% Stage 1, 14% Stage 2, 13% Stage 3) and 769 matched non-AKI adults, AKI was associated with higher adjusted rates of incident CKD (adjusted hazard ratio 3.98, 95% confidence interval 2.51-6.31), CKD progression (2.37,1.28-4.39), heart failure events (1.68, 1.22-2.31) and all-cause death (1.78, 1.24-2.56). AKI was not associated with major atherosclerotic cardiovascular events in multivariable analysis (0.95, 0.70-1.28). After accounting for degree of kidney function recovery and proteinuria at three months after discharge, the associations of AKI with heart failure (1.13, 0.80-1.61) and death (1.29, 0.84-1.98) were attenuated and no longer significant. Thus, assessing kidney function recovery and proteinuria status three months after AKI provides important prognostic information for long-term clinical outcomes.

Published
2021

6. A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death

Author

Chinchilli, Vernon M., Go, Alan S., Himmelfarb, Jonathan, Ikizler, T. Alp, Kaufman, James S., Kimmel, Paul L., Parikh, Chirag R., Stokes, John B., Coca, Steven, Garg, Amit, Zheng, Sijie, Pravoverov, Leonid, Hsu, Chi-yuan, Hsu, Raymond K., Liu, Kathleen D., Reeves, W. Brian, Siew, Edward D., Lewis, Julia B., Ware, Lorraine, Devarajan, Prasad, Krawczeski, Catherine, Bennett, Michael, Zappitelli, Michael, Wurfel, Mark, Coca, Steven G., Garg, Amit X., Wurfel, Mark M., Ware, Lorraine B., Faulkner, Georgia Brown, and Tan, Thida C.

Published
2021
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8. Natural language processing of electronic health records is superior to billing codes to identify symptom burden in hemodialysis patients

Author

Chan, Lili, primary, Beers, Kelly, additional, Yau, Amy A., additional, Chauhan, Kinsuk, additional, Duffy, Áine, additional, Chaudhary, Kumardeep, additional, Debnath, Neha, additional, Saha, Aparna, additional, Pattharanitima, Pattharawin, additional, Cho, Judy, additional, Kotanko, Peter, additional, Federman, Alex, additional, Coca, Steven G., additional, Van Vleck, Tielman, additional, and Nadkarni, Girish N., additional

Published
2020
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13. Analysis of OPTN/UNOS registry suggests the number of HLA matches and not mismatches is a stronger independent predictor of kidney transplant survival

Author

Yacoub, Rabi, primary, Nadkarni, Girish N., additional, Cravedi, Paolo, additional, He, John Cijiang, additional, Delaney, Veronica B., additional, Kent, Rebecca, additional, Chauhan, Kinsuk N., additional, Coca, Steven G., additional, Florman, Sander S., additional, Heeger, Peter S., additional, Murphy, Barbara, additional, and Menon, Madhav C., additional

Published
2018
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25. APOL1and blood pressure changes in young adults

Author

Nadkarni, Girish N. and Coca, Steven G.

Abstract

APOL1risk variants have been shown to be associated with kidney disease and hypertension. In this study, Chen and colleagues assess the association of these risk variants with longitudinal blood pressure in young adults. We review the current literature on association of these alleles with blood pressure and propose future directions to resolve the existing controversies.

Published
2017
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26. A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death

Author

Ikizler, T. Alp, Parikh, Chirag R., Himmelfarb, Jonathan, Chinchilli, Vernon M., Liu, Kathleen D., Coca, Steven G., Garg, Amit X., Hsu, Chi-yuan, Siew, Edward D., Wurfel, Mark M., Ware, Lorraine B., Faulkner, Georgia Brown, Tan, Thida C., Kaufman, James S., Kimmel, Paul L., Go, Alan S., Chinchilli, Vernon M., Go, Alan S., Himmelfarb, Jonathan, Ikizler, T. Alp, Kaufman, James S., Kimmel, Paul L., Parikh, Chirag R., Stokes, John B., Coca, Steven, Garg, Amit, Zheng, Sijie, Pravoverov, Leonid, Hsu, Chi-yuan, Hsu, Raymond K., Liu, Kathleen D., Reeves, W. Brian, Siew, Edward D., Lewis, Julia B., Ware, Lorraine, Devarajan, Prasad, Krawczeski, Catherine, Bennett, Michael, Zappitelli, Michael, and Wurfel, Mark

Abstract

Acute kidney injury (AKI) has been reported to be associated with excess risks of death, kidney disease progression and cardiovascular events although previous studies have important limitations. To further examine this, we prospectively studied adults from four clinical centers surviving three months and more after hospitalization with or without AKI who were matched on center, pre-admission CKD status, and an integrated priority score based on age, prior cardiovascular disease or diabetes mellitus, preadmission estimated glomerular filtration rate (eGFR) and treatment in the intensive care unit during the index hospitalization between December 2009-February 2015, with follow-up through November 2018. All participants had assessments of kidney function before (eGFR) and at three months and annually (eGFR and proteinuria) after the index hospitalization. Associations of AKI with outcomes were examined after accounting for pre-admission and three-month post-discharge factors. Among 769 AKI (73% Stage 1, 14% Stage 2, 13% Stage 3) and 769 matched non-AKI adults, AKI was associated with higher adjusted rates of incident CKD (adjusted hazard ratio 3.98, 95% confidence interval 2.51-6.31), CKD progression (2.37,1.28-4.39), heart failure events (1.68, 1.22-2.31) and all-cause death (1.78, 1.24-2.56). AKI was not associated with major atherosclerotic cardiovascular events in multivariable analysis (0.95, 0.70-1.28). After accounting for degree of kidney function recovery and proteinuria at three months after discharge, the associations of AKI with heart failure (1.13, 0.80-1.61) and death (1.29, 0.84-1.98) were attenuated and no longer significant. Thus, assessing kidney function recovery and proteinuria status three months after AKI provides important prognostic information for long-term clinical outcomes.

Published
2020
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