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Start Over Author "Timo Rieg" Journal kidney and blood pressure research
4 results on '"Timo Rieg"'

1. Central European Meeting on Hypertension and Cardiovascular Disease Prevention

Author

Cynthia M. Miracle, Patricia R. Wahl, Oliver Vonend, Mehmet Kanbay, Adrian Covic, Ali Akcay, Roland C. Blantz, Feridun Karakurt, Brigitta Rumberger, Scott C. Thomson, Peter Gerke, Krystyna Pawlak, J.S. Malyszko, Clemens Kreutz, Johannes Donauer, Michal Mysliwiec, Hanna Bachórzewska-Gajewska, E. Sitniewska, Sławomir Dobrzycki, Astrid Starke, Faruk Turgut, Bunyamin Isik, Ying Waeckerle-Men, Timo Rieg, Bernhard Banas, Jacek S. Malyszko, Stephan R. Orth, Jens Timmer, Gerd Walz, Rabia Alkan, Romana Rysava, Volker Vallon, Rudolf P. Wüthrich, Ramazan Yigitoglu, Kerstin Amann, Jochen Wilpert, Eberhard Ritz, Rolf Rohrbach, Günter Schiele, Maciej Szmitkowski, and S. Lawnicki

Subjects
medicine.medical_specialty, Nephrology, business.industry, medicine, Disease prevention, General Medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Published
2007

2. Combined Effects of Carbonic Anhydrase Inhibitor and Adenosine A1 Receptor Antagonist on Hemodynamic and Tubular Function in the Kidney

Author

Volker Vallon, Timo Rieg, Scott C. Thomson, Cynthia M. Miracle, and Roland C. Blantz

Subjects
medicine.medical_specialty, Kidney, genetic structures, biology, urogenital system, Chemistry, medicine.drug_class, Renal function, General Medicine, urologic and male genital diseases, Adenosine receptor, female genital diseases and pregnancy complications, Benzolamide, Adenosine A1 receptor, Endocrinology, medicine.anatomical_structure, Nephrology, Internal medicine, Carbonic anhydrase, medicine, biology.protein, Carbonic anhydrase inhibitor, sense organs, Cardiology and Cardiovascular Medicine, Tubuloglomerular feedback
Abstract

Background: Carbonic anhydrase inhibitors (CAI) reduce proximal reabsorption, activating tubuloglomerular feedback (TGF) and reducing glomerular filtration rate (GFR). Adenosine A1 receptors (A1R) mediate the TGF response and stimulate proximal reabsorption. Methods: Clearance and micropuncture studies were performed in Wistar rats to determine whether blockade of A1R (KW3902 0.3 mg/kg i.v.) would prevent CAI (benzolamide 5 mg/kg i.v.) from lowering GFR, whether CAI and KW3902 exert additive effects on sodium excretion, and to what extent such interactions depend on events in the glomerulus, proximal tubule, or distal nephron. Results: KW3902 raised GFR and prevented CAI from lowering GFR. KW3902 and CAI caused additive diuresis and natriuresis. KW3902 and CAI increased lithium clearance, but their effects were redundant. CAI increased the dependence of proximal reabsorption on active chloride transport. KW3902, alone, did likewise, but to a lesser extent than CAI. Adding KW3902 to CAI lessened the shift toward active chloride transport. Conclusions: The data reveal that A1R mediate glomerular vascular resistance whether or not TGF is activated, that additive effects of CAI and KW3902 on salt excretion occur, in part, because KW3902 inhibits reabsorption downstream from the macula densa, and that KW3902 likely inhibits proximal reabsorption by interfering with apical sodium-hydrogen exchange.

Published
2007

3. Contents Vol. 30, 2007

Author

Astrid Starke, Johannes Donauer, Michal Mysliwiec, Rudolf P. Wüthrich, Brigitta Rumberger, Patricia R. Wahl, Jens Timmer, Maciej Szmitkowski, Rabia Alkan, Krystyna Pawlak, Romana Rysava, Jochen Wilpert, Ying Waeckerle-Men, Clemens Kreutz, Hanna Bachórzewska-Gajewska, Volker Vallon, Scott C. Thomson, Stephan R. Orth, Bernhard Banas, Sławomir Dobrzycki, S. Lawnicki, Peter Gerke, Ramazan Yigitoglu, Kerstin Amann, Adrian Covic, Oliver Vonend, Mehmet Kanbay, Roland C. Blantz, Rolf Rohrbach, Gerd Walz, Eberhard Ritz, Günter Schiele, Jacek S. Malyszko, Ali Akcay, Cynthia M. Miracle, J.S. Malyszko, Feridun Karakurt, Bunyamin Isik, E. Sitniewska, Faruk Turgut, and Timo Rieg

Subjects
Nephrology, General Medicine, Cardiology and Cardiovascular Medicine
Published
2007

4. Subject Index Vol. 30, 2007

Author

Peter Gerke, Rolf Rohrbach, Günter Schiele, Bunyamin Isik, Volker Vallon, J.S. Malyszko, Scott C. Thomson, Sławomir Dobrzycki, Bernhard Banas, Maciej Szmitkowski, Ali Akcay, Jacek S. Malyszko, Rudolf P. Wüthrich, Astrid Starke, E. Sitniewska, Romana Rysava, Faruk Turgut, S. Lawnicki, Timo Rieg, Eberhard Ritz, Johannes Donauer, Michal Mysliwiec, Stephan R. Orth, Krystyna Pawlak, Jochen Wilpert, Adrian Covic, Roland C. Blantz, Ying Waeckerle-Men, Cynthia M. Miracle, Jens Timmer, Rabia Alkan, Patricia R. Wahl, Feridun Karakurt, Ramazan Yigitoglu, Kerstin Amann, Gerd Walz, Oliver Vonend, Mehmet Kanbay, Clemens Kreutz, Hanna Bachórzewska-Gajewska, and Brigitta Rumberger

Subjects
Index (economics), Nephrology, Statistics, Subject (documents), General Medicine, Cardiology and Cardiovascular Medicine, Mathematics
Published
2007

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