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The enormous interest currently given to colitis in general and their treatment in particular prompts me to share the methods that I have been using for many years and with great success in the treatment of colitis of infectious origin, which include colitis caused by an infection of a very diverse nature: or entering the intestine from the outside , such as amoeba dysenteriae Councilman et Lafleur s. entamoeba hystolytica Schaudinn, bac. dysenteriae Schiga-Kruse s. bacterium dysenteriae Migula, bac. Flexner'a, bac. His-Roussel'a, bac. Strong'a, pseudo-dysentery bacilli, or developing due to increased virulence of the regulars of the intestine, for example, b. coli, b. proteus, streptococci, etc., or, finally, colitis, as a complication in other infectious diseases, for example, with typhoid fever, measles, flu, etc., and all these forms of colitis are so similar to each other that it is impossible to distinguish them from each other neither by clinical signs, nor by the course: there may be mild and severe cases, acute and chronic, regardless of their origin; one and the same symptomatology is reduced to local and general phenomena; in the latter case, as a result of the general intoxication of the body with the waste products of the intestinal flora absorbed from the intestine (feverish state, coated tongue, headaches, general fatigue, darkening of consciousness, convulsions, decline in heart activity, etc.); as for the symptoms of local origin, they boil down to colicky abdominal pain, increased urge to lower, tenesmus, secretion of blood and mucus, as an expression of intoxication of the mucous membrane of the colon and rectum, caused by the same intestinal flora. All these symptoms in their entirety and essence form the basis of the course and direction of the doctor's thought at the patient's bedside. We have to think, as G.I.Ivashentsev quite reasonably states1), about the destruction and elimination of the infectious principle, the neutralization and elimination of toxins, the prevention and treatment of severe lesions of the colon mucosa. All these conditions are met in the best way by our method of treatment. In the current state of our knowledge, the specific treatment of colitis recedes into the background.