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Your search keyword '"Jones-Engel, Lisa"' showing total 6 results
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6 results on '"Jones-Engel, Lisa"'

2. Simian Foamy Virus Infection of Rhesus Macaques in Bangladesh: Relationship of Latent Proviruses and Transcriptionally Active Viruses

Author

Soliven, Khanh, primary, Wang, Xiaoxing, additional, Small, Christopher T., additional, Feeroz, Mostafa M., additional, Lee, Eun-Gyung, additional, Craig, Karen L., additional, Hasan, Kamrul, additional, Engel, Gregory A., additional, Jones-Engel, Lisa, additional, Matsen, Frederick A., additional, and Linial, Maxine L., additional

Published
2013
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5. Sensitive Assays for Simian Foamy Viruses Reveal a High Prevalence of Infection in Commensal, Free-Ranging Asian Monkeys

Author

Jones-Engel, Lisa, primary, Steinkraus, Katherine A., additional, Murray, Shannon M., additional, Engel, Gregory A., additional, Grant, Richard, additional, Aggimarangsee, Nantiya, additional, Lee, Benjamin P. Y.-H., additional, May, Cynthia, additional, Schillaci, Michael A., additional, Somgird, Chaleamchat, additional, Sutthipat, Tulyawat, additional, Vojtech, Lucia, additional, Zhao, JianYuan, additional, and Linial, Maxine L., additional

Published
2007
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6. New World simian foamy virus infections in vivo and in vitro.

Author

Stenbak CR, Craig KL, Ivanov SB, Wang X, Soliven KC, Jackson DL, Gutierrez GA, Engel G, Jones-Engel L, and Linial ML

Subjects
Animals, Base Sequence, Cell Line, Humans, Macaca mulatta, Molecular Sequence Data, Platyrrhini, Simian foamy virus genetics, Simian foamy virus isolation & purification, Zoonoses transmission, Zoonoses virology, Monkey Diseases virology, Retroviridae Infections veterinary, Retroviridae Infections virology, Simian foamy virus physiology
Abstract

Foamy viruses (FV) are complex retroviruses that naturally infect all nonhuman primates (NHP) studied to date. Zoonotic transmission of Old World NHP simian foamy viruses (SFV) has been documented, leading to nonpathogenic persistent infections. To date, there have been no reports concerning zoonotic transmission of New World monkey (NWM) SFV to humans and resulting infection. In this study, we developed a Western blot assay to detect antibodies to NWM SFV, a nested PCR assay to detect NWM SFV DNA, and a β-galactosidase-containing indicator cell line to assay replication of NWM SFV. Using these tools, we analyzed the plasma and blood of 116 primatologists, of whom 69 had reported exposures to NWM. While 8 of the primatologists tested were seropositive for SFV from a NWM, the spider monkey, none had detectable levels of viral DNA in their blood. We found that SFV isolated from three different species of NWM replicated in some, but not all, human cell lines. From our data, we conclude that while humans exposed to NWM SFV produce antibodies, there is no evidence for long-term viral persistence.

Published
2014
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