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5. PD19-10 PATIENT AND DISEASE SPECIFIC RISK FACTORS AND NERVE SPARING HAVE A SIGNIFICANT IMPACT ON LONG TERM SEXUAL FUNCTIONAL FOLLOWING MINIMALLY INVASIVE RADICAL PROSTATECTOMY

Author

Natasha Bhate, Joanne Sethi, Hashim U. Ahmed, Mathias Winkler, Nicholas Raison, Gledisa Musollari, Alexandra Forde, Kathy Man, and Suks Minhas

Subjects
Disease specific, medicine.medical_specialty, Nerve sparing, Erectile dysfunction, Prostatectomy, business.industry, Urology, medicine.medical_treatment, Peri, medicine, business, medicine.disease
Abstract

INTRODUCTION AND OBJECTIVE:Erectile dysfunction remains a major source of morbidity for patients following radical prostatectomy (RP). This study aims to identify patient related as well as peri- a...

Published
2021
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6. MP31-04 DOES INTRACYTOPLASMIC MORPHOLOGICALLY SELECTED SPERM INJECTION IMPROVE LIVE BIRTH RATES COMPARED TO ICSI IN MEN WITH INFERTILITY AND RAISED SPERM DNA FRAGMENTATION?

Author

Tharu Tharakan, James D.M. Nicopoullos, Jaya Parikh, Meen-Yau Thum, Suks Minhas, Runzhi Chen, Sheena E.M. Lewis, Tet Yap, and Channa N. Jayasena

Subjects
Infertility, Andrology, Assisted reproductive technology, business.industry, Urology, medicine.medical_treatment, Medicine, DNA fragmentation, business, Live birth, medicine.disease, Sperm injection
Abstract

INTRODUCTION AND OBJECTIVE:There is conflicting evidence on the role of intracytoplasmic morphologically selected sperm injection (IMSI) in assisted reproductive technology (ART), and whether it in...

Published
2021
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11. MP15-20 COST ESTIMATION OF COMMONLY USED DISPOSABLES DURING URETEROSCOPY

Author

Mahad Minhas, Jessica A. Mandeville, Sari Khaleel, and Michael S. Borofsky

Subjects
medicine.medical_specialty, medicine.diagnostic_test, Cost estimate, business.industry, Urology, medicine, Medical physics, Ureteroscopy, urologic and male genital diseases, business
Abstract

INTRODUCTION AND OBJECTIVE:Research suggests that surgeon awareness of surgical supply cost is lacking. We wanted to assess the ability of urologists and their operating room (OR) staff to estimate...

Published
2020
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12. Systematic Review and Meta-Analysis—Is there a Benefit in Using Neoadjuvant Systemic Chemotherapy for Locally Advanced Penile Squamous Cell Carcinoma?

Author

Azizi, Mounsif, primary, Aydin, Ahmet M., additional, Hajiran, Ali, additional, Lai, Andrew, additional, Kumar, Ambuj, additional, Peyton, Charles C., additional, Minhas, Suks, additional, Sonpavde, Guru P., additional, Chahoud, Jad, additional, Pagliaro, Lance C., additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2020
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13. Reply by Authors

Author

Azizi, Mounsif, primary, Aydin, Ahmet M., additional, Hajiran, Ali, additional, Lai, Andrew, additional, Kumar, Ambuj, additional, Peyton, Charles C., additional, Minhas, Suks, additional, Sonpavde, Guru P., additional, Chahoud, Jad, additional, Pagliaro, Lance C., additional, Necchi, Andrea, additional, and Spiess, Philippe E., additional

Published
2020
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17. MP78-10 A COMPARISON OF CANCER CONTROL OUTCOMES AT 5 YEARS OF FOCAL THERAPY (USING HIFU & CRYOTHERAPY) TO RADICAL PROSTATECTOMY FOR CLINICALLY SIGNIFICANT NON-METASTATIC PROSTATE CANCER: PROPENSITY SCORE-MATCHED ANALYSIS

Author

Caroline M. Moore, Jaspal Virdi, Daniel Ball, Feargus Hosking-Jervis, Raj Nigam, Deepika Reddy, Naveed Afzal, Hashim U. Ahmed, Mark Emberton, Neil McCartan, McCracken Stuart, Tim Dudderidge, Stephanie Guillaumier, Massimo Valerio, Saiful Miah, Max Peters, Peter S.N. van Rossum, David Eldred-Evans, Annie Kim, Enrique Gómez Gómez, Raj Persad, Henry Lewi, Manit Arya, Chris Ogden, Richard Hindley, Mathias Winkler, Suks Minhas, Taimur T. Shah, and Greene Damian

Subjects
medicine.medical_specialty, Prostatectomy, business.industry, Urology, medicine.medical_treatment, Cryotherapy, medicine.disease, Focal therapy, Prostate cancer, Cancer control, Propensity score matching, medicine, Non metastatic, business
Abstract

INTRODUCTION AND OBJECTIVES:Focal therapy (FT) has a low side-effect profile but there is uncertainty about its medium-long term cancer control compared to radical approaches. Both focal HIFU and f...

Published
2019
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18. MP75-01 EVIDENCE THAT TESTICULAR SPERM HAS IMPROVED DNA INTEGRITY COMPARED TO EJACULATED SPERM IN INFERTILE MEN

Author

Jonathan Ramsay, Tharu Tharakan, Sheena E.M. Lewis, Lona Vyas, Suks Minhas, and Channa N. Jayasena

Subjects
Dna integrity, Andrology, genetic structures, Ejaculated sperm, business.industry, Urology, Recurrent miscarriage, Sperm dna, Medicine, business, medicine.disease, Sperm
Abstract

INTRODUCTION AND OBJECTIVES:There is increasing evidence that the integrity of sperm DNA may be associated with recurrent miscarriage and failure of implantation. The objective of this study was to...

Published
2019
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19. MP71-15 PREVALENCE OF RECURRENT EXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) URINARY TRACT INFECTIONS (UTIS) IN PATIENTS WITHIN A UROLOGY SERVICE. INTRODUCING THE CONCEPT OF FAECAL MICROBIOTA TRANSPLANTATION (FMT) AS A TREATMENT MODALITY

Author

Suks Minhas, Christine Gan, Vaishali Ferizoli, Mark Thursz, Frances Davies, Ranan Dasgupta, Rohma Ghani, Julian Marchesi, and Benjamin H. Mullish

Subjects
medicine.medical_specialty, business.industry, Urology, Urinary system, medicine.medical_treatment, fungi, food and beverages, urologic and male genital diseases, bacterial infections and mycoses, Faecal microbiota transplantation, Treatment modality, Internal medicine, Beta-lactamase, Medicine, In patient, business
Abstract

INTRODUCTION AND OBJECTIVES:Patients with an underlying urological diagnosis colonised with multidrug-resistant organisms (MDRO) such as ESBL are predisposed to recurrent UTIs. Treatment can be pro...

Published
2019
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21. MP30-11 PREDICTORS OF POOR FUNCTIONAL OUTCOMES AFTER FOCAL HIGH INTENSITY FOCUSSED ULTRASOUND (HIFU)

Author

Stephanie Guillaumier, Chris Ogden, Raj Persad, Raj Nigam, Manit Arya, Naveed Afzal, Jaspal Virdi, Richard Hindley, Hashim U. Ahmed, Taimur T. Shah, Mark Emberton, Tim Dudderidge, Max Peters, Feargus Hosking-Jervis, Caroline M. Moore, Henry Lewi, Mathias Winkler, Karishma Shah, Suks Minhas, and Neil McCartan

Subjects
medicine.medical_specialty, business.industry, Urology, High intensity, Ultrasound, medicine, Radiology, business
Published
2018
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23. MP07-12 A UK MULTICENTRE STUDY ANALYSING THE SURGICAL SPERM RETRIEVAL RATES IN MEN WITH NON -MOSAIC KLINEFELTER’S SYNDROME UNDERGOING MTESE

Author

Amr Abdel Raheem, Tet Yap, P. Sangster, Majid Shabbir, Marcus Heller, Sameer Poselay, Yasmeen Zainal, Thomas Johnson, Mark H. Johnson, Chirag Bhandari, Suks Minhas, David Ralph, Khaled S. Hafez, Bahar Mohammadi, and andrew vicens

Subjects
Gynecology, medicine.medical_specialty, S syndrome, business.industry, Urology, Sperm Retrieval, Medicine, Mosaic (geodemography), business
Published
2018
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26. MP78-10 A COMPARISON OF CANCER CONTROL OUTCOMES AT 5 YEARS OF FOCAL THERAPY (USING HIFU & CRYOTHERAPY) TO RADICAL PROSTATECTOMY FOR CLINICALLY SIGNIFICANT NON-METASTATIC PROSTATE CANCER: PROPENSITY SCORE-MATCHED ANALYSIS

Author

Shah, Taimur T., primary, Peters, Max, additional, Reddy*, Deepika, additional, Ball, Daniel, additional, Kim, Annie, additional, Gomez, Enrique Gomez, additional, Miah, Saiful, additional, Eldred-Evans, David, additional, Guillaumier, Stephanie, additional, Hosking-Jervis, Feargus, additional, van Rossum, Peter S.N., additional, Dudderidge, Tim, additional, Hindley, Richard, additional, Stuart, McCracken, additional, Damian, Greene, additional, Nigam, Raj, additional, Valerio, Massimo, additional, Minhas, Suks, additional, Afzal, Naveed, additional, Lewi, Henry, additional, McCartan, Neil, additional, Ogden, Chris, additional, Persad, Raj, additional, Virdi, Jaspal, additional, Moore, Caroline, additional, Arya, Manit, additional, Emberton, Mark, additional, Ahmed, Hashim U., additional, and Winkler, Mathias, additional

Published
2019
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27. MP71-15 PREVALENCE OF RECURRENT EXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) URINARY TRACT INFECTIONS (UTIS) IN PATIENTS WITHIN A UROLOGY SERVICE. INTRODUCING THE CONCEPT OF FAECAL MICROBIOTA TRANSPLANTATION (FMT) AS A TREATMENT MODALITY

Author

Ghani*, Rohma, primary, Gan, Christine, additional, Mullish, Benjamin, additional, Ferizoli, Vaishali, additional, Marchesi, Julian, additional, Thursz, Mark, additional, Davies, Frances, additional, Dasgupta, Ranan, additional, and Minhas, Suks, additional

Published
2019
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31. MP07-12 A UK MULTICENTRE STUDY ANALYSING THE SURGICAL SPERM RETRIEVAL RATES IN MEN WITH NON -MOSAIC KLINEFELTER’S SYNDROME UNDERGOING MTESE

Author

sangster, philippa, primary, Johnson, Mark, additional, Raheem, Amr, additional, Zainal, Yasmeen, additional, Poselay, Sameer, additional, Heller, Marcus, additional, Mohammadi, Bahar, additional, Johnson, Thomas, additional, Hafez, Khaled, additional, bhandari, chirag, additional, vicens, andrew, additional, yap, tet, additional, shabbir, majid, additional, minhas, Suks, additional, and Ralph, David, additional

Published
2018
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34. MP30-11 PREDICTORS OF POOR FUNCTIONAL OUTCOMES AFTER FOCAL HIGH INTENSITY FOCUSSED ULTRASOUND (HIFU)

Author

Shah, Taimur T, primary, Peters, Max, additional, Guillaumier, Stephanie, additional, Arya, Manit, additional, Afzal, Naveed, additional, Hosking-Jervis, Feargus, additional, Dudderidge, Tim, additional, Hindley, Richard, additional, Lewi, Henry, additional, McCartan, Neil, additional, Moore, Caroline M, additional, Nigam, Raj, additional, Ogden, Chris, additional, Persad, Raj, additional, Shah, Karishma, additional, Virdi, Jaspal, additional, Winkler, Mathias, additional, Emberton, Mark, additional, Ahmed, Hashim U., additional, and Minhas, Suks, additional

Published
2018
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42. Conservative Surgery for Squamous Cell Carcinoma of the Penis: Resection Margins and Long-Term Oncological Control

Author

Majid Shabbir, Raj Nigam, Suks Minhas, Peter Malone, Asif Muneer, Prodromos Philippou, and David Ralph

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Urologic Surgical Procedures, Male, Multivariate analysis, Urology, Urologic Surgical Procedure, Carcinoma, Humans, Medicine, Penile cancer, Prospective Studies, Prospective cohort study, Penile Neoplasms, Survival analysis, Aged, Aged, 80 and over, business.industry, Middle Aged, medicine.disease, Surgery, Treatment Outcome, Disease-specific Survival Rate, medicine.anatomical_structure, Carcinoma, Squamous Cell, Neoplasm Recurrence, Local, business, Penis, Follow-Up Studies
Abstract

We assessed the oncological outcome of penile conserving surgery and identified parameters predicting local recurrence, including resection margins.A total of 179 patients with invasive penile cancer treated with organ sparing surgery at a tertiary center between 2002 and 2010 fulfilled our study criteria. Demographic, histopathological, management and followup data were recorded in a prospective database. Local, regional and distant recurrence rates, time to recurrence and survival rates were calculated. Survival analysis was performed by the Kaplan-Meier method. Multivariate analysis was used to identify predictors of local recurrence.Mean followup was 42.8 months (range 4 to 107). Local, regional and distant metastatic recurrence developed in 16 (8.9%), 19 (10.6%) and 9 patients (5.0%) at a mean of 26.1, 26.8 and 11.7 months, respectively. The 5-year disease specific survival rate after recurrence was 54.7% (95% CI 46.1-63.3). For patients with isolated local recurrence the 5-year disease specific survival rate was 91.7% compared to 38.4% for those with regional recurrence. The overall 5-year local recurrence-free rate was 86.3% (95% CI 82.6-90.4). Tumor grade (p = 0.003), stage (p = 0.021) and lymphovascular invasion (p = 0.014) were identified as predictors of local recurrence on multivariate analysis.Penile conserving surgery is oncologically safe and a surgical excision margin of less than 5 mm is adequate. Higher local recurrence rates are associated with lymphovascular invasion, and higher tumor stage and grade. Local recurrence has no negative impact on long-term survival.

Published
2012
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44. PD52-03 CYTOGENETIC ABNORMALITIES IN MEN WITH SUBFERTILITY. ANALYSIS OF THE FREQUENCY OF ABNORMALITIES AND DETERMINATION OF A THRESHOLD SPERM CONCENTRATION FOR GENETIC TESTING

Author

Saad Abumelha, David Ralph, Nim Christopher, Giulio Garaffa, Fahd Almashat, Francesco De Luca, Tet Yap, Suks Minhas, and Amr Abdel Raheem

Subjects
Gynecology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Urology, medicine, business, Sperm, Genetic testing
Published
2015
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45. MP43-13 ERECTILE FUNCTION IN PATIENTS AFTER RADICAL PROSTATECTOMY IN HIGH-RISK PROSTATE CANCER: RECOVERY AND OUTCOME ANALYSIS

Author

Tim Briggs, Paul Cathcart, Senthil Nathan, Tet Yap, Suks Minhas, John F. Kelly, John Hines, and Ashwin Sridhar

Subjects
medicine.medical_specialty, Prostate cancer, Prostatectomy, business.industry, Urology, medicine.medical_treatment, medicine, Outcome analysis, In patient, Erectile function, medicine.disease, business
Published
2015
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50. MP45-15 A PROSPECTIVE ANALYSIS OF THE EFFECTS OF FOCAL THERAPY FOR PROSTATE CANCER ON ERECTILE FUNCTION FROM A COMBINED ANALYSIS OF 3 PROSPECTIVE TRIALS

Author

Tet Yap, Stephanie Guillaumier, Neil McCartan, Louise Dickinson, Hashim U. Ahmed, Richard Hindley, Susan C. Charman, Suks Minhas, and Mark Emberton

Subjects
Response rate (survey), medicine.medical_specialty, Wilcoxon signed-rank test, Proportional hazards model, business.industry, Urology, Incidence (epidemiology), urologic and male genital diseases, medicine.disease, Prospective analysis, Prostate cancer, Exact test, Quality of life, Internal medicine, medicine, business
Abstract

rates to QOL surveys, as well as factors associated with response, in these two patient populations. METHODS: Patients who underwent surgery for RCC or PCa at our institution between 2006 and 2012 were offered enrollment in a prospective registry that included baseline and annual QoL assessment. We identified 201 patients in the RCC registry and 616 patients in the PCa registry who completed a baseline QoL survey and were mailed a follow-up QoL at one and two years post surgery [RCC: SF-36, FACTeG (73 questions), PCa: EPIC, IIEF, Max-PC (80 questions)]. We compared patient characteristics between responders (i.e. those that returned at least a one or two-year follow-up) and non-responders using a Wilcoxon rank-sum test for continuous variables and a Fisher’s Exact test for categorical variables. To compare cancer-specific survival (CSS) between responders and non-responders we employed Cox Proportional Hazards models. All statistical tests were two-sided, with significance set at p1⁄4 0.05. RESULTS: The overall response rate for the PCa and RCC groups were 63% and 48% (p

Published
2014
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