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A preliminary study to assess objectively the effects of dicyclomine upon uncontrolled detrusor contractions and bladder capacity was undertaken in 14 patients with a cystometric diagnosis of uninhibited neurogenic bladder. Response was measured by cystometry performed 1, 2 and 4 hours after a 20 mg. oral dose. Of the 14 patients 11 had significant blockade of uninhibited contractions and a concomitant increase in bladder capacity. Similar but less dramatic changes were noted in the remaining 3 patients. Dicyclomine seems to have effective anticholinergic properties. No remarkable side effects were observed.

Simultaneous presentation of obstructing ureteral calculi and untreated primary hyperparathyroidism offers an interesting therapeutic dilemma. We herein review 8 cases, with 6 occurring in the last 3 years. When both conditions require surgical intervention the parathyroid adenoma should be excised first. The adenoma and offending stone can be removed at the same operation, with resultant prompt relief of pain and decrease in hospitalization.

Low dose heparin prophylaxis has proved effective in reducing postoperative thromboembolic complications in a series combining multiple types of surgical procedures. Our series comfirms its safety for transurethral operations. We recommend its use in patients with predisposing factors to thromboembolic complications.